Host SNAREs mediate fusion of vacuoles containing Legionella pneumophila with vesicles exiting the endoplasmic reticulum
Arasaki K, Roy C. Host SNAREs mediate fusion of vacuoles containing Legionella pneumophila with vesicles exiting the endoplasmic reticulum. The FASEB Journal 2009, 23: 867.4-867.4. DOI: 10.1096/fasebj.23.1_supplement.867.4.Peer-Reviewed Original ResearchPlasma membrane-derived vacuoleEarly secretory vesiclesSNARE complexSNARE proteinsSecretory vesiclesPlasma membrane t-SNAREFunctional SNARE complexesPlasma membrane syntaxinsEndoplasmic reticulum-derived vesiclesLegionella pneumophilaT-SNAREsSyntaxin 4Mechanism of fusionSpecialized organellesSyntaxin 2Syntaxin 3Mammalian cellsEndoplasmic reticulumSec22bSNAP23SyntaxinBacterial uptakeLocalization studiesIntracellular pathogensBacterial replicationSyntaxin 11 Contributes to the Interferon-Inducible Restriction of Coxiella burnetii Intracellular Infection
Ganesan S, Alvarez N, Steiner S, Fowler K, Corona A, Roy C. Syntaxin 11 Contributes to the Interferon-Inducible Restriction of Coxiella burnetii Intracellular Infection. MBio 2023, 14: e03545-22. PMID: 36728431, PMCID: PMC9972978, DOI: 10.1128/mbio.03545-22.Peer-Reviewed Original ResearchConceptsC. burnetii replicationSNARE proteinsHost cellsSyntaxin-11Cell-autonomous responsesIntracellular pathogensMembrane fusion eventsLysosome-derived organellesDefense mechanismsModel bacterial pathogenMultiple cell typesEukaryotic cellsDefense pathwaysDelivery of cargoReplication of pathogensHuman proteinsFusion eventsDissemination of pathogensFusion pathwayHost proteinsIntrinsic defense mechanismsHost vesiclesHost restriction factorsStable expressionSubcellular organelles