2017
Multiparameter Single Cell Profiling of Airway Inflammatory Cells
Yao Y, Welp T, Liu Q, Niu N, Wang X, Britto CJ, Krishnaswamy S, Chupp G, Montgomery RR. Multiparameter Single Cell Profiling of Airway Inflammatory Cells. Cytometry Part B Clinical Cytometry 2017, 92: 12-20. PMID: 27807928, PMCID: PMC5250532, DOI: 10.1002/cyto.b.21491.Peer-Reviewed Original ResearchConceptsSingle-cell methodsComplex trait diseasesSubgroup of asthmaticsSingle-cell analysisMultiparameter single cell analysisMillions of patientsTranscriptional analysisImmunologic underpinningsInduced sputumAirway diseaseAsthmatic patientsAirway samplesCell subsetsImmune statusFunctional statusClinical severityDistinct biologic mechanismsTreatment successPhysiologic manifestationsBiologic mechanismsCystic fibrosisCellular analysisPatientsCytometry studiesU.S. population
2016
Respiratory Viral Infections in Chronic Lung Diseases
Britto CJ, Brady V, Lee S, Dela Cruz CS. Respiratory Viral Infections in Chronic Lung Diseases. Clinics In Chest Medicine 2016, 38: 87-96. PMID: 28159164, PMCID: PMC5679206, DOI: 10.1016/j.ccm.2016.11.014.Peer-Reviewed Original ResearchConceptsChronic lung diseaseChronic obstructive pulmonary diseaseInterstitial lung diseaseLung diseaseLung infectionViral infectionCystic fibrosisRespiratory viral infectionsObstructive pulmonary diseaseDifferent lung diseasesDisease exacerbationPulmonary diseaseDisease pathogenesisInfectionDiseaseAsthmaExacerbationPatientsFibrosisPathogenesisProgression