2022
Alcohol and cannabis co‐use and longitudinal gray matter volumetric changes in early and late adolescence
Luo X, Yang JJ, Buu A, Trucco EM, Li C. Alcohol and cannabis co‐use and longitudinal gray matter volumetric changes in early and late adolescence. Addiction Biology 2022, 27: e13208. PMID: 36001427, PMCID: PMC9413216, DOI: 10.1111/adb.13208.Peer-Reviewed Original ResearchConceptsGray matter volumeLate adolescenceCaudal middle frontal cortexEarly adolescent onsetGray matter volumetric changesMiddle frontal cortexSevere alcohol useBrain developmentCross-sectional findingsSocial cognitionExecutive controlNCANDA studyVolumetric declinesSupramarginal gyrusPotential sex differencesSuperior temporalImpact of alcoholAdolescent onsetSubstance useCortical regionsAlcohol useMatter volumeFrontal cortexResult of alcoholMixed-effects modeling
2015
Resting‐state functional connectivity of the striatum in early‐stage Parkinson's disease: Cognitive decline and motor symptomatology
Manza P, Zhang S, Li C, Leung H. Resting‐state functional connectivity of the striatum in early‐stage Parkinson's disease: Cognitive decline and motor symptomatology. Human Brain Mapping 2015, 37: 648-662. PMID: 26566885, PMCID: PMC4843498, DOI: 10.1002/hbm.23056.Peer-Reviewed Original ResearchConceptsParkinson's diseaseFunctional connectivity patternsMotor deficitsFunctional connectivityRostral anterior cingulate cortexState functional connectivity patternsAnterior cingulate cortexConnectivity patternsAnterior putamenMotor symptomsSubstantia nigraDopaminergic functionHealthy controlsMotor functionDorsal caudateStriatal connectivityStriatal subregionsSymptomatic individualsMotor impairmentCingulate cortexCognitive declineNeurodegenerative disordersCognitive functionDiseaseEarly stage individuals