2020
Neural Responses to Reward in a Gambling Task: Sex Differences and Individual Variation in Reward-Driven Impulsivity
Li G, Zhang S, Le TM, Tang X, Li CR. Neural Responses to Reward in a Gambling Task: Sex Differences and Individual Variation in Reward-Driven Impulsivity. Cerebral Cortex Communications 2020, 1: tgaa025. PMID: 32864617, PMCID: PMC7446303, DOI: 10.1093/texcom/tgaa025.Peer-Reviewed Original ResearchGambling TaskNeural processesImpulse controlRegional activationSex differencesDorsal anterior cingulate cortexPrefrontal cortical activationAnterior cingulate cortexReaction timeHuman Connectome ProjectCautious respondingReward sensitivityIndividual variationNeural responsesBehavioral measuresAngular gyrusLonger reaction timesPrefrontal cortexImpulsivityCingulate cortexCortical activationConnectome ProjectHigher activationTaskReward
2019
The effects of age on reward magnitude processing in the monetary incentive delay task
Dhingra I, Zhang S, Zhornitsky S, Le T, Wang W, Chao HH, Levy I, Li CR. The effects of age on reward magnitude processing in the monetary incentive delay task. NeuroImage 2019, 207: 116368. PMID: 31743790, PMCID: PMC7463276, DOI: 10.1016/j.neuroimage.2019.116368.Peer-Reviewed Original ResearchConceptsMonetary incentive delay taskIncentive delay taskSupplementary motor areaMagnitude of rewardAge-related differencesDelay taskRT differencesRegional activationAge effectsEffect of ageReaction time differencesRight anterior insulaMiddle frontal gyrusReward-directed behaviorExplicit cuesMagnitude processingBrain activationRight caudate headAnterior insulaFrontal gyrusReward magnitudeLarge rewardPrimary motor cortexCerebral processesParahippocampal gyrusInterdependent Neural Correlates of Reward and Punishment Sensitivity During Rewarded Action and Inhibition of Action
Le TM, Wang W, Zhornitsky S, Dhingra I, Zhang S, Li CR. Interdependent Neural Correlates of Reward and Punishment Sensitivity During Rewarded Action and Inhibition of Action. Cerebral Cortex 2019, 30: 1662-1676. PMID: 31667492, PMCID: PMC7132903, DOI: 10.1093/cercor/bhz194.Peer-Reviewed Original ResearchConceptsInhibition of actionNeural correlatesReinforcement Sensitivity TheoryRostral anterior cingulate cortexMiddle frontal gyrusAnterior cingulate cortexPunishment sensitivityReinforcement sensitivityMFG activityIndividual differencesNeural processesReward QuestionnaireTrait sensitivityBrain correlatesNeural substratesFrontal gyrusGo responseRewarded actionsSensitivity theoryIncorrect responsesMediation analysisCingulate cortexRegional activationBehavioral approachAvoidance behaviorSocial anxiety, posterior insula activation, and autonomic response during self-initiated action in a Cyberball game
Wang W, Zhornitsky S, Li CS, Le TM, Joormann J, Li CR. Social anxiety, posterior insula activation, and autonomic response during self-initiated action in a Cyberball game. Journal Of Affective Disorders 2019, 255: 158-167. PMID: 31153052, PMCID: PMC6591038, DOI: 10.1016/j.jad.2019.05.046.Peer-Reviewed Original ResearchConceptsSelf-initiated actionsPosterior insula activationSocial anxietyCyberball gameInsula activationPhysiological arousalHigher skin conductance responsesHigh social anxietySevere social anxietyHigher physiological arousalSkin conductance responsesSkin conductance dataPotential sex effectsEffect of depressionSocial exclusionInsula responseNeural correlatesNeural processesLA individualsConductance responsesLimbic activationRegional activationSkin conductanceAnxietyLA group
2018
Motor Preparation Disrupts Proactive Control in the Stop Signal Task
Wang W, Hu S, Ide JS, Zhornitsky S, Zhang S, Yu AJ, Li CR. Motor Preparation Disrupts Proactive Control in the Stop Signal Task. Frontiers In Human Neuroscience 2018, 12: 151. PMID: 29780308, PMCID: PMC5945807, DOI: 10.3389/fnhum.2018.00151.Peer-Reviewed Original ResearchStop-signal taskGranger causal connectivityMotor preparationSignal taskMotor preparatory activityFP activationCausal connectivityMotor responseTrial reaction timeDirect neural evidenceConflict anticipationBrain activationTrialsSequential effectsSuccess rateRegional activationResponse slowingActivationPreparatory activityCertain individualsDifferent patternsHigh levelsControlSlowingNeural evidence
2016
The Right Superior Frontal Gyrus and Individual Variation in Proactive Control of Impulsive Response
Hu S, Ide JS, Zhang S, Li CR. The Right Superior Frontal Gyrus and Individual Variation in Proactive Control of Impulsive Response. Journal Of Neuroscience 2016, 36: 12688-12696. PMID: 27974616, PMCID: PMC5157110, DOI: 10.1523/jneurosci.1175-16.2016.Peer-Reviewed Original ResearchConceptsStop-signal reaction timeRight superior frontal gyrusSuperior frontal gyrusConflict anticipationProactive controlFrontal gyrusImpulsive responsesCognitive controlSignal taskInhibitory controlImpulse controlRegional activationEfficient response inhibitionReaction time differencesMotor urgencyVentromedial prefrontal cortexStop-signal taskYoung adultsSignal reaction timePosterior cingulate cortexIndividual variationError RTAction restraintNeural basisResponse inhibitionA dual but asymmetric role of the dorsal anterior cingulate cortex in response inhibition and switching from a non-salient to salient action
Manza P, Hu S, Chao HH, Zhang S, Leung HC, Li CS. A dual but asymmetric role of the dorsal anterior cingulate cortex in response inhibition and switching from a non-salient to salient action. NeuroImage 2016, 134: 466-474. PMID: 27126003, PMCID: PMC4912860, DOI: 10.1016/j.neuroimage.2016.04.055.Peer-Reviewed Original ResearchConceptsDorsal anterior cingulate cortexStop-signal reaction timeAnterior cingulate cortexSignal reaction timeCingulate cortexResponse inhibitionMotor inhibitionPre-supplementary motor areaRegional activationPre-SMA functionRegional brain activationMotor response inhibitionMotor areaStop trialsSalience processingBrain activationSalience detectionSuccess trialsSignal taskTrialsInhibitionSuccessful inhibitionInfrequent stimuliCortexActivation
2015
Individual variation in the neural processes of motor decisions in the stop signal task: the influence of novelty seeking and harm avoidance personality traits
Hu J, Lee D, Hu S, Zhang S, Chao H, Li CS. Individual variation in the neural processes of motor decisions in the stop signal task: the influence of novelty seeking and harm avoidance personality traits. Brain Structure And Function 2015, 221: 2607-2618. PMID: 25989852, PMCID: PMC4654717, DOI: 10.1007/s00429-015-1061-4.Peer-Reviewed Original ResearchConceptsStop-signal taskHarm avoidanceNeural processesSignal taskPersonality traitsStudy of cognitionWhole-brain regressionRegional brain activationRisk-taking processesCognitive controlExecutive controlStop errorBrain activationFMRI studyBehavioral tasksMotor decisionsFrontopolar cortexMonetary rewardsNovelty seekingRisk-taking responsesBilateral orbitofrontalExplicit manipulationDorsomedial prefrontalRegional activationParahippocampal gyrus
2014
Functional Clustering of the Human Inferior Parietal Lobule by Whole-Brain Connectivity Mapping of Resting-State Functional Magnetic Resonance Imaging Signals
Zhang S, Li CS. Functional Clustering of the Human Inferior Parietal Lobule by Whole-Brain Connectivity Mapping of Resting-State Functional Magnetic Resonance Imaging Signals. Brain Connectivity 2014, 4: 53-69. PMID: 24308753, PMCID: PMC3929139, DOI: 10.1089/brain.2013.0191.Peer-Reviewed Original ResearchConceptsInferior parietal lobuleHuman inferior parietal lobuleParietal lobulePosterior inferior parietal lobuleFunctional magnetic resonance imaging (fMRI) dataResting-state functional magnetic resonance imaging (fMRI) dataInferior frontal gyrusFunctional magnetic resonance imaging (fMRI) signalsEarlier fMRI studiesDefault mode networkSpatial attentionCognitive challengesIntraparietal sulcusFMRI studyMathematical cognitionFrontal gyrusAngular gyrusSupramarginal gyrusHemispheric differencesMode networkMagnetic resonance imaging dataFunctional segregationRegional activationLanguage processingPosterior subregions
2013
Error processing and gender-shared and -specific neural predictors of relapse in cocaine dependence
Luo X, Zhang S, Hu S, Bednarski SR, Erdman E, Farr OM, Hong KI, Sinha R, Mazure CM, Li CS. Error processing and gender-shared and -specific neural predictors of relapse in cocaine dependence. Brain 2013, 136: 1231-1244. PMID: 23485852, PMCID: PMC3613717, DOI: 10.1093/brain/awt040.Peer-Reviewed Original ResearchConceptsDorsal anterior cingulate cortexFunctional magnetic resonance imagingCognitive controlError-related activationError processingCocaine-dependent individualsAnterior cingulate cortexSignal taskCingulate cortexCocaine dependenceFunctional magnetic resonance imaging (fMRI) dataStop-signal taskTreatment-seeking individualsCross-sectional findingsModerate-sized cohortsBrain activationBehavioral treatmentNeural predictorsDrug useMagnetic resonance imaging dataStatistical Parametric Mapping 8Regional activationPsychosocial factorsSuccess trialsMagnetic resonance imaging
2012
Cerebral correlates of skin conductance responses in a cognitive task
Zhang S, Hu S, Chao HH, Luo X, Farr OM, Li CS. Cerebral correlates of skin conductance responses in a cognitive task. NeuroImage 2012, 62: 1489-1498. PMID: 22634217, PMCID: PMC3408848, DOI: 10.1016/j.neuroimage.2012.05.036.Peer-Reviewed Original ResearchConceptsSkin conductance responsesSupplementary motor areaControl of arousalDorsal anterior cingulate cortexAnterior cingulate cortexRegional activationFunctional magnetic resonance imagingMagnetic resonance imagingMedial prefrontal cortexLower skin conductance responsesMotor areaCingulate cortexResonance imagingPrefrontal cortexCerebral correlatesConductance responsesTrialsSuccess trialsNeural activityStop successSignal taskPhysiological arousalCognitive performanceNeural correlatesCortex
2008
Neural Correlates of Post-error Slowing during a Stop Signal Task: A Functional Magnetic Resonance Imaging Study
Li CS, Huang C, Yan P, Paliwal P, Constable RT, Sinha R. Neural Correlates of Post-error Slowing during a Stop Signal Task: A Functional Magnetic Resonance Imaging Study. Journal Of Cognitive Neuroscience 2008, 20: 1021-1029. PMID: 18211230, PMCID: PMC2597347, DOI: 10.1162/jocn.2008.20071.Peer-Reviewed Original ResearchConceptsStop-signal taskPost-error slowingBehavioral adjustmentNeural correlatesSignal taskFunctional magnetic resonance imaging studyFunctional magnetic resonance imagingVentrolateral prefrontal cortexCortical brain regionsMagnetic resonance imaging studyResonance imaging studyElicit errorsError processingStop trialsPrefrontal cortexNeural circuitryGo signalRegional activationBehavioral outputBrain regionsStop signalReaction timeConflicting responsesTaskImaging studies