2024
Sex differences in the effects of individual anxiety state on regional responses to negative emotional scenes
Chaudhary S, Wong H, Chen Y, Zhang S, Li C. Sex differences in the effects of individual anxiety state on regional responses to negative emotional scenes. Biology Of Sex Differences 2024, 15: 15. PMID: 38351045, PMCID: PMC10863151, DOI: 10.1186/s13293-024-00591-6.Peer-Reviewed Original ResearchConceptsMedial prefrontal cortexState-Trait Anxiety InventoryFunctional magnetic resonance imagingState-Trait Anxiety Inventory scoresSuperior frontal gyrusGeneralized psychophysiological interactionEmotional processingFrontal gyrusLingual gyrusMedial prefrontal cortex connectivityMedial prefrontal cortex activationSex differencesRight inferior frontal gyrusResponse to negative emotionsRight superior frontal gyrusFunctional magnetic resonance imaging dataReaction timeImpact emotional processingNegative emotion processingInferior frontal gyrusLeft parahippocampal gyrusNegative emotional scenesMarkers of anxietyRepeated-measures analysis of covarianceLevels of anxiety
2022
Cerebral Volumetric Correlates of Apathy in Alzheimer’s Disease and Cognitively Normal Older Adults: Meta-Analysis, Label-Based Review, and Study of an Independent Cohort
Chaudhary S, Zhornitsky S, Chao HH, van Dyck CH, Li CR. Cerebral Volumetric Correlates of Apathy in Alzheimer’s Disease and Cognitively Normal Older Adults: Meta-Analysis, Label-Based Review, and Study of an Independent Cohort. Journal Of Alzheimer's Disease 2022, 85: 1251-1265. PMID: 34924392, PMCID: PMC9215906, DOI: 10.3233/jad-215316.Peer-Reviewed Original ResearchConceptsAlzheimer's diseaseInferior frontal gyrusIndependent cohortEmotional scoresHealthy controlsCognitive impairmentVolumetric correlatesMini-Mental State Examination scoreAD/mild cognitive impairmentNeuroanatomical correlatesState Examination scoreApathy Evaluation ScaleGray matter volumeVoxel-based morphometryRight inferior frontal gyrusLabel-based reviewMild cognitive impairmentNormal older adultsCortical atrophyHigh morbidityBasal gangliaRight putamenMatter volumeAnterior cingulateReduced quality
2021
Symptom provocation in obsessive–compulsive disorder: A voxel-based meta-analysis and meta-analytic connectivity modeling
Yu J, Zhou P, Yuan S, Wu Y, Wang C, Zhang N, Li CR, Liu N. Symptom provocation in obsessive–compulsive disorder: A voxel-based meta-analysis and meta-analytic connectivity modeling. Journal Of Psychiatric Research 2021, 146: 125-134. PMID: 34971910, DOI: 10.1016/j.jpsychires.2021.12.029.Peer-Reviewed Original ResearchConceptsRight lateral occipital gyrusMiddle occipital gyrusMiddle cingulate cortexLateral occipital gyrusRight caudate bodyMiddle temporal gyrusObsessive-compulsive disorderInferior frontal gyrusSymptom provocationOCD patientsOrbitofrontal cortexCaudate bodyPrimary analysisThalamic-cortical circuit [CSTC] dysfunctionOccipital gyrusPosterior cortical structuresMagnetic resonance imaging studyActivation likelihood estimation algorithmHigher activationRight middle temporal gyrusRight orbitofrontal cortexLeft orbitofrontal cortexResonance imaging studyFunctional magnetic resonance imaging studyDorsal striatal activationCognitive dysfunction and cerebral volumetric deficits in individuals with Alzheimer's disease, alcohol use disorder, and dual diagnosis
Zhornitsky S, Chaudhary S, Le TM, Chen Y, Zhang S, Potvin S, Chao HH, van Dyck CH, Li CR. Cognitive dysfunction and cerebral volumetric deficits in individuals with Alzheimer's disease, alcohol use disorder, and dual diagnosis. Psychiatry Research Neuroimaging 2021, 317: 111380. PMID: 34482052, PMCID: PMC8579376, DOI: 10.1016/j.pscychresns.2021.111380.Peer-Reviewed Original ResearchConceptsAlcohol use disorderAlzheimer's diseaseHippocampal formationUse disordersHigher Clinical Dementia Rating Scale-SumVentricular volumeVolumetric deficitsCingulate cortexClinical Dementia Rating Scale SumCoordinating CenterSmaller hippocampal volumesLarger ventricular volumesNational Alzheimer's Coordinating CenterIsthmus cingulate cortexPosterior cingulate cortexMisuse of alcoholSuperior parietal cortexDistinct brain regionsCognitive dysfunctionHippocampal volumeInferior frontal gyrusRegional GMVHigh riskDementia severityDual diagnosisSex differences in attention deficit hyperactivity symptom severity and functional connectivity of the dorsal striatum in young adults
Chen Y, Li G, Ide J, Luo X, Li C. Sex differences in attention deficit hyperactivity symptom severity and functional connectivity of the dorsal striatum in young adults. Neuroimage Reports 2021, 1: 100025. DOI: 10.1016/j.ynirp.2021.100025.Peer-Reviewed Original ResearchAttention deficit hyperactivity disorderADHD total scoreGroup 2Functional connectivityDorsal striatumGroup 3Symptom severityGroup 1Sex differencesTotal scoreFrontal gyrusRight inferior parietal gyrusRight superior frontal gyrusBasal ganglia dysfunctionCaudate functional connectivitySupplementary motor areaDorsal anterior cingulate cortexAnterior cingulate cortexSeed-based correlationSuperior frontal gyrusGreater symptom severityInferior parietal gyrusDeficit hyperactivity disorderGanglia dysfunctionInferior frontal gyrus
2018
Diminished gray matter density mediates chemotherapy dosage-related cognitive impairment in breast cancer patients
Li X, Chen H, Lv Y, Chao HH, Gong L, Li CR, Cheng H. Diminished gray matter density mediates chemotherapy dosage-related cognitive impairment in breast cancer patients. Scientific Reports 2018, 8: 13801. PMID: 30218006, PMCID: PMC6138678, DOI: 10.1038/s41598-018-32257-w.Peer-Reviewed Original ResearchConceptsBreast cancer patientsGray matter densityRight middle frontal gyrusBC patientsCancer patientsCognitive impairmentMiddle frontal gyrusChemotherapy cyclesFrontal gyrusWhole brainGray matterMorphometry analysisHealthy control subjectsStructural magnetic resonance imagingDose-response relationshipMagnetic resonance imagingRight fusiform areaFrontal cortical structuresControl subjectsBilateral cerebellumInferior frontal gyrusPatientsLeft inferior frontal gyrusResonance imagingBrain structures
2016
Craving behavioral intervention for internet gaming disorder: remediation of functional connectivity of the ventral striatum
Zhang J, Ma S, Li C, Liu L, Xia C, Lan J, Wang L, Liu B, Yao Y, Fang X. Craving behavioral intervention for internet gaming disorder: remediation of functional connectivity of the ventral striatum. Addiction Biology 2016, 23: 337-346. PMID: 27894158, PMCID: PMC5446940, DOI: 10.1111/adb.12474.Peer-Reviewed Original ResearchConceptsResting-state functional connectivityPsychobehavioral interventionsIGD subjectsFunctional connectivityHealthy controlsInternet gaming disorderGreater resting-state functional connectivityFrontal gyrusEffects of CBICross-sectional studyBehavioral intervention studyDirect current stimulationInferior parietal lobuleMiddle frontal gyrusGaming disorderSeverity of IGDInferior frontal gyrusSimilar time intervalsEffective treatmentIntervention studiesNon-invasive techniquePotential biomarkersVentral striatumParietal lobuleCurrent stimulationPower spectrum scale invariance as a neural marker of cocaine misuse and altered cognitive control
Ide JS, Hu S, Zhang S, Mujica-Parodi LR, Li CS. Power spectrum scale invariance as a neural marker of cocaine misuse and altered cognitive control. NeuroImage Clinical 2016, 11: 349-356. PMID: 27294029, PMCID: PMC4888196, DOI: 10.1016/j.nicl.2016.03.004.Peer-Reviewed Original ResearchConceptsPower spectrum scale invarianceCognitive controlInferior frontal gyrusNeural markersBehavioral adjustmentSupramarginal gyrusLeft inferior frontal gyrusFunctional magnetic resonance imagingFronto-parietal areasBlood oxygenation level-dependent (BOLD) signalCocaine misuseLevel-dependent signalCocaine-dependent adultsSignal taskFrontal gyrusFrontoparietal regionsPrefrontal cortexMagnetic resonance imagingConnectivity dynamicsBehavioral variablesCerebral activityCocaine addictionCocaine exposureCocaine dependenceDependent adultsAssociation of Drinking Problems and Duration of Alcohol Use to Inhibitory Control in Nondependent Young Adult Social Drinkers
Hu S, Zhang S, Chao HH, Krystal JH, Li CS. Association of Drinking Problems and Duration of Alcohol Use to Inhibitory Control in Nondependent Young Adult Social Drinkers. Alcohol Clinical And Experimental Research 2016, 40: 319-328. PMID: 26833431, PMCID: PMC4742397, DOI: 10.1111/acer.12964.Peer-Reviewed Original ResearchConceptsAlcohol Use Disorders Identification TestYears of drinkingStop-signal reaction timeAlcohol useAge-related changesAlcohol misuseInhibitory controlAUDIT scoresDrinking problemsNondependent drinkersProlonged stop signal reaction timeChronic alcohol useAnterior cingulate cortexPresupplementary motor areaDisorders Identification TestRight inferior frontal gyrusResponse inhibitionSuperior temporal gyrusYoung adult social drinkersFunctional magnetic resonanceAdult social drinkersSignal reaction timeCerebral responsesInferior frontal gyrusHigher AUDIT
2014
Functional Clustering of the Human Inferior Parietal Lobule by Whole-Brain Connectivity Mapping of Resting-State Functional Magnetic Resonance Imaging Signals
Zhang S, Li CS. Functional Clustering of the Human Inferior Parietal Lobule by Whole-Brain Connectivity Mapping of Resting-State Functional Magnetic Resonance Imaging Signals. Brain Connectivity 2014, 4: 53-69. PMID: 24308753, PMCID: PMC3929139, DOI: 10.1089/brain.2013.0191.Peer-Reviewed Original ResearchConceptsInferior parietal lobuleHuman inferior parietal lobuleParietal lobulePosterior inferior parietal lobuleFunctional magnetic resonance imaging (fMRI) dataResting-state functional magnetic resonance imaging (fMRI) dataInferior frontal gyrusFunctional magnetic resonance imaging (fMRI) signalsEarlier fMRI studiesDefault mode networkSpatial attentionCognitive challengesIntraparietal sulcusFMRI studyMathematical cognitionFrontal gyrusAngular gyrusSupramarginal gyrusHemispheric differencesMode networkMagnetic resonance imaging dataFunctional segregationRegional activationLanguage processingPosterior subregions