2023
Correlation of Immune-Inflammatory Response System (IRS)/Compensatory Immune-Regulatory Reflex System (CIRS) with White Matter Integrity in First-Episode Patients with Schizophrenia
Gou M, Li W, Tong J, Zhou Y, Xie T, Yu T, Feng W, Li Y, Chen S, Tian B, Tan S, Wang Z, Pan S, Luo X, Li C, Zhang P, Huang J, Tian L, Hong L, Tan Y. Correlation of Immune-Inflammatory Response System (IRS)/Compensatory Immune-Regulatory Reflex System (CIRS) with White Matter Integrity in First-Episode Patients with Schizophrenia. Molecular Neurobiology 2023, 61: 2754-2763. PMID: 37932545, DOI: 10.1007/s12035-023-03694-0.Peer-Reviewed Original ResearchImmune-inflammatory response systemWhite matter integrityEnzyme-linked immunosorbent assayDiffusion tensor imagingD effect sizesFractional anisotropyWhole-brain white matter integritySex-matched healthy controlsReflex systemPlasma cytokine levelsFirst-episode patientsBrains of patientsBrain white matter integrityCortico-spinal tractNegative Syndrome ScaleCohen's d effect sizesAverage fractional anisotropyImmune imbalancePeripheral cytokinesCytokine levelsInflammatory mediatorsEpisode patientsPathophysiological mechanismsWhite matter microstructureFunctional dysconnectivity
2018
Ventral striatal dysfunction in cocaine dependence – difference mapping for subregional resting state functional connectivity
Zhang S, Li CR. Ventral striatal dysfunction in cocaine dependence – difference mapping for subregional resting state functional connectivity. Translational Psychiatry 2018, 8: 119. PMID: 29915214, PMCID: PMC6006289, DOI: 10.1038/s41398-018-0164-0.Peer-Reviewed Original ResearchConceptsState functional connectivityCocaine dependenceVentral striatumFunctional connectivityVentral striatal dysfunctionExtent of depressionCircuit deficitsDopaminergic deficitFunctional dysconnectivityStriatal dysfunctionRSFC differencesVmPFC connectivitySubregional changesRsFC changesParahippocampal gyrusCocaine cravingCortical connectivityHealthy populationVentromedial prefrontal cortexVisual cortexMental illnessCocaine useRSFCPrefrontal cortexFunctional subregions