2018
Thalamic Cortical Error–Related Responses in Adult Social Drinkers: Sex Differences and Problem Alcohol Use
Ide JS, Zhornitsky S, Chao HH, Zhang S, Hu S, Wang W, Krystal JH, Li CR. Thalamic Cortical Error–Related Responses in Adult Social Drinkers: Sex Differences and Problem Alcohol Use. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2018, 3: 868-877. PMID: 29859929, PMCID: PMC6177312, DOI: 10.1016/j.bpsc.2018.04.008.Peer-Reviewed Original ResearchConceptsWhole-brain linear regressionError-related activationSex differencesBilateral dorsal anterior cingulate cortexAlcohol Use Disorders Identification Test (AUDIT) scoresSocial drinkersDorsal anterior cingulate cortexSubstance use disordersAnterior cingulate cortexFunctional magnetic resonance imagingMagnetic resonance imagingSuperior temporal cortexStatistical parametric mappingProblem alcohol useBilateral thalamusAlcohol drinkersAdult social drinkersStop-signal taskMale social drinkersTemporal cortexUse disordersCerebral activationIndependent sample t-testCingulate cortexSubcortical regions
2014
The Effects of Methylphenidate on Cerebral Activations to Salient Stimuli in Healthy Adults
Farr OM, Hu S, Matuskey D, Zhang S, Abdelghany O, Li CS. The Effects of Methylphenidate on Cerebral Activations to Salient Stimuli in Healthy Adults. Experimental And Clinical Psychopharmacology 2014, 22: 154-165. PMID: 24188171, PMCID: PMC4105943, DOI: 10.1037/a0034465.Peer-Reviewed Original ResearchConceptsStop-signal taskSalient stimuliSaliency processingFunctional MRIAttention deficit hyperactivity disorderRight inferior parietal cortexHigh motivational valueDeficit hyperactivity disorderEffects of methylphenidateInferior parietal cortexHealthy adultsNeural basisCognitive functioningMotivational valueAttention disordersHyperactivity disorderBilateral caudate headCatecholaminergic signalingMethylphenidate groupParietal cortexCerebral activationHigher activationCatecholaminergic treatmentPrimary motor cortexCerebral activity
2013
Methylphenidate remediates error-preceding activation of the default mode brain regions in cocaine-addicted individuals
Matuskey D, Luo X, Zhang S, Morgan PT, Abdelghany O, Malison RT, Li CS. Methylphenidate remediates error-preceding activation of the default mode brain regions in cocaine-addicted individuals. Psychiatry Research 2013, 214: 116-121. PMID: 23973363, PMCID: PMC3811038, DOI: 10.1016/j.pscychresns.2013.06.009.Peer-Reviewed Original ResearchMeSH KeywordsAdultCentral Nervous System StimulantsCerebral CortexCocaine-Related DisordersCognition DisordersFemaleHumansImage Processing, Computer-AssistedInhibition, PsychologicalMagnetic Resonance ImagingMaleMethylphenidateMiddle AgedModels, NeurologicalNeural PathwaysNeuropsychological TestsOxygenPhotic StimulationReaction TimeConceptsFunctional magnetic resonance imagingStop-signal taskCD individualsCerebral activationPrecuneus/posterior cingulate cortexSystolic blood pressureInfluence of methylphenidateEffects of methylphenidateMagnetic resonance imagingPosterior cingulate cortexBrain imaging studiesCocaine-addicted individualsDefault mode networkAgonist therapyBlood pressureIntravenous methylphenidateCortico-striatoHealthy controlsCocaine-dependent individualsThalamic activationCingulate cortexResonance imagingBrain regionsMethylphenidateCocaine dependence
2012
The influence of risky and conservative mental sets on cerebral activations of cognitive control
Winkler AD, Hu S, Li CS. The influence of risky and conservative mental sets on cerebral activations of cognitive control. International Journal Of Psychophysiology 2012, 87: 254-261. PMID: 22922525, PMCID: PMC3511622, DOI: 10.1016/j.ijpsycho.2012.08.010.Peer-Reviewed Original ResearchConceptsStop-signal taskMental setCognitive controlSignal taskCerebral activationPre-supplementary motor areaGo reaction timePrevious imaging workReaction timeReward uncertaintyCognitive functioningIndividual differencesStop errorGreater activationNeural responsesSalient eventsContextual effectsImaging workRetrosplenial cortexMore salientAdult participantsMotor areaSuccess trialsCerebral responsesRewardThe effects of age on cerebral activations: internally versus externally driven processes
Hu S, Chao H, Winkler AD, Li CS. The effects of age on cerebral activations: internally versus externally driven processes. Frontiers In Aging Neuroscience 2012, 4: 4. PMID: 22536185, PMCID: PMC3334814, DOI: 10.3389/fnagi.2012.00004.Peer-Reviewed Original ResearchFunctional magnetic resonance imagingCerebral activationRegional brain activationAge-related decreaseCognitive processesPrepotent responsesPsychological constructsCognitive functioningSignal taskBrain activationGo trialsFMRI dataGo signalSE trialsEffect of ageImaging literatureYoung adultsStop signalHealthy adultsInfluence of ageSeeming inconsistencyAdultsMagnetic resonance imagingYears of ageFunctioning
2011
Deficits in default mode network activity preceding error in cocaine dependent individuals
Bednarski SR, Zhang S, Hong KI, Sinha R, Rounsaville BJ, Li CS. Deficits in default mode network activity preceding error in cocaine dependent individuals. Drug And Alcohol Dependence 2011, 119: e51-e57. PMID: 21703783, PMCID: PMC3188675, DOI: 10.1016/j.drugalcdep.2011.05.026.Peer-Reviewed Original ResearchConceptsDefault mode networkCocaine dependenceCocaine useHealthy controlsTask-related cerebral activationBlood oxygenation level-dependent (BOLD) signalDemographics-matched healthy controlsGray matter volumeDefault mode network activityLevel-dependent signalChronic cocaine useRegional brain activationPosterior cingulate cortexStatistical parametric mappingCerebral functionBilateral precuneusCocaine-dependent individualsCerebral activationHealthy peopleMatter volumeCingulate cortexVentromedial prefrontal cortexBrain regionsCognitive deficitsCocaine misuse