2014
18F-FDG PET/CT can be used to detect non-functioning pancreatic neuroendocrine tumors
Luo G, Liu Z, Guo M, Jin K, Xiao Z, Liu L, Xu J, Zhang B, Liu C, Huang D, Hu S, Ni Q, Long J, Yu X. 18F-FDG PET/CT can be used to detect non-functioning pancreatic neuroendocrine tumors. International Journal Of Oncology 2014, 45: 1531-1536. PMID: 25096059, DOI: 10.3892/ijo.2014.2570.Peer-Reviewed Original ResearchConceptsNon-functioning pancreatic neuroendocrine tumorsPancreatic neuroendocrine tumorsPET/CTNeuroendocrine tumorsNon-functioning endocrine pancreatic tumorsPET/CT scansDistant metastatic lesionsShanghai Cancer CenterEndocrine pancreatic tumorsClinical characteristicsMetastatic lesionsTumor sizeCancer CenterTNM stagePancreatic tumorsLarge cohortCT scanClinical valueAdvanced stageSignificant associationTumorsPatientsCTCohortLesions
2011
Genomic analysis identifies association of Fusobacterium with colorectal carcinoma
Kostic A, Gevers D, Pedamallu C, Michaud M, Duke F, Earl A, Ojesina A, Jung J, Bass A, Tabernero J, Baselga J, Liu C, Shivdasani R, Ogino S, Birren B, Huttenhower C, Garrett W, Meyerson M. Genomic analysis identifies association of Fusobacterium with colorectal carcinoma. Genome Research 2011, 22: 292-298. PMID: 22009990, PMCID: PMC3266036, DOI: 10.1101/gr.126573.111.Peer-Reviewed Original ResearchConceptsColorectal carcinomaColorectal carcinoma pathogenesisColorectal tumorsCarcinomaTumor microenvironmentTumor/normal pairsNonneoplastic cellsCancer cellsWhole genome sequencesPrecise roleTumorsMicrobiotaRDNA sequence analysisQuantitative PCRFurther investigationComplex communitiesGenome sequenceGenomic analysisSequence analysisFirmicutes phylumFusobacteriaNormal pairsCellsDiverse collectionDNA pairs
2010
DNA Aptamers as Molecular Probes for Colorectal Cancer Study
Sefah K, Meng L, Lopez-Colon D, Jimenez E, Liu C, Tan W. DNA Aptamers as Molecular Probes for Colorectal Cancer Study. PLOS ONE 2010, 5: e14269. PMID: 21170319, PMCID: PMC3000811, DOI: 10.1371/journal.pone.0014269.Peer-Reviewed Original ResearchConceptsColorectal cancerAppropriate therapeutic regimensCell-based systematic evolutionColorectal Cancer StudyMolecular featuresMultistep carcinogenic processCancer cell linesCell line DLD-1Therapeutic regimensNormal colon cellsPrognostic markerDifferent tumorsSpecific tumorsFlow cytometrySpecific biomarkersEarly disease detectionCarcinogenic processTumorsCancerSpecific markersCancer studiesColon cellsDLD-1Cell linesDisease development
2006
Presentation and Management of Gastrointestinal Stromal Tumors of the Duodenum
Winfield R, Hochwald S, Vogel S, Hemming A, Liu C, Cance W, Grobmyer S. Presentation and Management of Gastrointestinal Stromal Tumors of the Duodenum. The American Surgeon 2006, 72: 719-723. PMID: 16913316, DOI: 10.1177/000313480607200811.Peer-Reviewed Original ResearchConceptsDuodenal gastrointestinal stromal tumorGastrointestinal stromal tumorsSmall bowel gastrointestinal stromal tumorsGastric gastrointestinal stromal tumorsStromal tumorsPartial duodenal resectionHistory of neurofibromatosisPortion of duodenumDuodenal resectionGastrointestinal bleedingMedian sizeAdjuvant therapyCommon presentationComplete resectionRetrospective reviewSmall bowelRare tumorCase reportSingle institutionIncidental findingPatientsPancreaticoduodenectomyResectionTumorsDuodenum
2005
A crucial role for antigen-presenting cells and alloantigen expression in graft-versus-leukemia responses
Reddy P, Maeda Y, Liu C, Krijanovski O, Korngold R, Ferrara J. A crucial role for antigen-presenting cells and alloantigen expression in graft-versus-leukemia responses. Nature Medicine 2005, 11: 1244-1249. PMID: 16227991, DOI: 10.1038/nm1309.Peer-Reviewed Original ResearchConceptsBone marrow transplantationAllogeneic bone marrow transplantationGVL responseLeukemia responseAlloantigen expressionInduction of graftAntigen-presenting cellsHost diseaseSerious complicationsDonor APCsMarrow transplantationTumor burdenTumor modelGraftAPCHost originPotent formResponseImmunotherapyCellsComplicationsTransplantationAcuityExpressionTumors
2004
Stabilized β-catenin promotes hepatocyte proliferation and inhibits TNFα-induced apoptosis
Shang X, Zhu H, Lin K, Tu Z, Chen J, Nelson D, Liu C. Stabilized β-catenin promotes hepatocyte proliferation and inhibits TNFα-induced apoptosis. Laboratory Investigation 2004, 84: 332-341. PMID: 14767485, DOI: 10.1038/labinvest.3700043.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsApoptosisBeta CateninCarcinoma, HepatocellularCell DivisionCell LineCell Line, TumorCell Transformation, NeoplasticCyclin D1Cytoskeletal ProteinsDrug StabilityGene Expression RegulationGenes, mycHepatocytesHumansLiver NeoplasmsMiceMice, SCIDMutationTrans-ActivatorsTransfectionTumor Necrosis Factor-alphaConceptsHuman hepatocellular carcinomaHepatocyte proliferationCell linesCommon malignant tumorCell proliferationImmune-deficient miceCell survival abilityLiver cell growthMurine hepatocyte cell lineCell growthHepatocyte cell lineAnchorage-independent cell growthMalignant tumorsHepatocellular carcinomaLiver cancerCyclin D1Inhibits TNFαOncogenic transformationCell apoptosisBeta-catenin mutationsAct DΒ-cateninPotential roleC-MycTumors
2003
β-Catenin Is Expressed Aberrantly in Tumors Expressing Shadow Cells
Hassanein A, Glanz S, Kessler H, Eskin T, Liu C. β-Catenin Is Expressed Aberrantly in Tumors Expressing Shadow Cells. American Journal Of Clinical Pathology 2003, 120: 732-736. PMID: 14608900, DOI: 10.1309/ealeg7ld6w7167px.Peer-Reviewed Original Research