2015
Effects of Alcohol metabolism on Hepatocellular carcinoma progression
Puszyk W, Hlady R, Tiedemann R, Robertson K, Liu C. Effects of Alcohol metabolism on Hepatocellular carcinoma progression. The FASEB Journal 2015, 29 DOI: 10.1096/fasebj.29.1_supplement.45.8.Peer-Reviewed Original ResearchHepatocellular carcinomaTumor progressionModel of HCCRisk of developmentHepatocellular carcinoma progressionEffects of alcoholCancer deathCommon causeAlcohol consumptionCell culture modelCarcinoma progressionCIMP cancersAlcohol metabolismEthanol metabolismTumor developmentProgressionCancerCulture modelPrimary tissuesDNA methylationMethylation abnormalitiesGene targetsMetabolismCarcinomaAbnormalities
2012
Iron Regulator Hepcidin Exhibits Antiviral Activity against Hepatitis C Virus
Liu H, Le Trinh T, Dong H, Keith R, Nelson D, Liu C. Iron Regulator Hepcidin Exhibits Antiviral Activity against Hepatitis C Virus. PLOS ONE 2012, 7: e46631. PMID: 23110054, PMCID: PMC3478283, DOI: 10.1371/journal.pone.0046631.Peer-Reviewed Original ResearchConceptsHCV infectionHepcidin expressionSerious chronic liver diseaseAntiviral activityHepatitis C viral infectionHepcidin expression levelsChronic HCV infectionChronic liver diseaseC viral infectionHepatitis C virusDirect antiviral activityIntracellular antiviral stateHepatocellular carcinoma progressionInnate antiviral defenseLiver diseaseC virusAntiviral effectHCV replicationIron overloadHepatocellular carcinomaExhibit antiviral activityHCVViral infectionSuppressive effectAmino acid peptide