2019
Donor T Cell Independent Mechanism May Contribute to Enhancing Steroid Refractory Gvhd in Murine Models
Toubai T, Rossi C, Tawara I, Liu C, Suto M, Matsuki E, Zajac C, Oravecz-Wilson K, Peltier D, Sun Y, Fujiwara H, Wu J, Riwes M, Heing I, Kim S, Reddy P. Donor T Cell Independent Mechanism May Contribute to Enhancing Steroid Refractory Gvhd in Murine Models. Transplantation And Cellular Therapy 2019, 25: s292-s293. DOI: 10.1016/j.bbmt.2018.12.669.Peer-Reviewed Original ResearchGVHD clinical scoresSR-GVHDSteroid-refractory GVHDDonor T cellsSplenic T cellsT cellsSteroid-refractoryClinical scoresRefractory GVHDMurine modelGut epithelial cellsWeight lossHistopathological scoresEpithelial cellsT cell-independent mechanismExhausted T cellsGVHD target organsMemory T cellsTarget organsT-cell characteristicsSerum inflammatory cytokinesResponse to DEXBody weight lossDevelopment of therapiesProgressive weight loss
2018
Donor T Cell Independent Mechanism Is Critical for Mediating Steroid Refractory Gvhd in Murine Models
Toubai T, Rossi C, Tawara I, Liu C, Zajac C, Oravecz-Wilson K, Peltier D, Sun Y, Fujiwara H, Riwes M, Henig I, Kim S, Suto M, Ishizawa K, Reddy P. Donor T Cell Independent Mechanism Is Critical for Mediating Steroid Refractory Gvhd in Murine Models. Blood 2018, 132: 4529-4529. DOI: 10.1182/blood-2018-99-114634.Peer-Reviewed Original ResearchGraft-versus-host diseaseAcute graft-versus-host diseaseGVHD clinical scoresBone marrow transplantationT cell-independent mechanismDonor T cellsSR-GVHDHuman leukocyte antigenSplenic T cellsT cellsSteroid-refractoryClinical scoresAllo-HCTBone marrowMurine modelAbstract Acute graft-versus-host diseaseGraft-versus-host disease target organsSteroid-refractory graft-versus-host diseaseProgressive graft-versus-host diseaseRefractory graft-versus-host diseaseGut epithelial cellsMurine bone marrow transplantationHistopathological scoresWeight lossDays of DEX treatment