2012
Combining cognitive behavioral therapy and contingency management to enhance their effects in treating cannabis dependence: less can be more, more or less
Carroll KM, Nich C, LaPaglia DM, Peters EN, Easton CJ, Petry NM. Combining cognitive behavioral therapy and contingency management to enhance their effects in treating cannabis dependence: less can be more, more or less. Addiction 2012, 107: 1650-1659. PMID: 22404223, PMCID: PMC3509418, DOI: 10.1111/j.1360-0443.2012.03877.x.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyContingency managementHomework completionTime-line follow-back methodTreatment-seeking young adultsCannabis dependenceAddition of CBTSession attendanceOut-patient treatment programDays of cannabisCannabis treatment outcomesCBT outcomeBehavioral therapyAbstinence conditionSkills trainingRandom effects regression analysisAlone conditionCriminal justice systemUrine specimensTreatment programYoung adultsWeekly urineEffects regression analysisJustice systemAbstinence
2010
Cognitive Function and Treatment Response in a Randomized Clinical Trial of Computer-Based Training in Cognitive-Behavioral Therapy
Carroll KM, Kiluk BD, Nich C, Babuscio TA, Brewer JA, Potenza MN, Ball SA, Martino S, Rounsaville BJ, Lejuez CW. Cognitive Function and Treatment Response in a Randomized Clinical Trial of Computer-Based Training in Cognitive-Behavioral Therapy. Substance Use & Misuse 2010, 46: 23-34. PMID: 21190403, PMCID: PMC3083447, DOI: 10.3109/10826084.2011.521069.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyCognitive functionComputer-assisted cognitive behavioral therapyComputer-assisted versionCognitive demandsCognitive functioningRisk takingPoor substanceSubstance usersHomework assignmentsHigh levelsClinical trialsSecondary analysisFunctioningRandomized clinical trialsParticipantsTreatment responseTakingTrainingSessionsSuch patientsQuality versus quantity: acquisition of coping skills following computerized cognitive–behavioral therapy for substance use disorders
Kiluk BD, Nich C, Babuscio T, Carroll KM. Quality versus quantity: acquisition of coping skills following computerized cognitive–behavioral therapy for substance use disorders. Addiction 2010, 105: 2120-2127. PMID: 20854334, PMCID: PMC2975828, DOI: 10.1111/j.1360-0443.2010.03076.x.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyComputerized CBT programEffects of CBTComputerized cognitive behavioral therapySubstance use disordersEffect of treatmentSubstance use outcomesRole-play taskTreatment completionHigh riskPrimary drugUse disordersAverage ageCommunity settingsBehavioral therapyPatient treatmentSubstance dependenceAlcohol useCBT programSubstance useUse outcomesComputerized versionParticipants' durationSignificant increaseTreatmentTreatment process, alliance and outcome in brief versus extended treatments for marijuana dependence
Gibbons CJ, Nich C, Steinberg K, Roffman RA, Corvino J, Babor TF, Carroll KM. Treatment process, alliance and outcome in brief versus extended treatments for marijuana dependence. Addiction 2010, 105: 1799-1808. PMID: 20840200, PMCID: PMC3422659, DOI: 10.1111/j.1360-0443.2010.03047.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmbulatory CareAnalysis of VarianceClinical CompetenceClinical ProtocolsCognitive Behavioral TherapyData Interpretation, StatisticalFemaleGuideline AdherenceHumansMaleMarijuana AbuseMotivationOutcome and Process Assessment, Health CarePhysician-Patient RelationsPsychometricsPsychotherapy, BriefRegression AnalysisTime Factors
2007
Contingency Management to Reduce Substance Use in Individuals Who are Homeless with Co-Occurring Psychiatric Disorders
Tracy K, Babuscio T, Nich C, Kiluk B, Carroll KM, Petry NM, Rounsaville BJ. Contingency Management to Reduce Substance Use in Individuals Who are Homeless with Co-Occurring Psychiatric Disorders. The American Journal Of Drug And Alcohol Abuse 2007, 33: 253-258. PMID: 17497548, PMCID: PMC3390023, DOI: 10.1080/00952990601174931.Peer-Reviewed Original Research
2006
Naltrexone and Disulfiram in Patients with Alcohol Dependence and Comorbid Post-Traumatic Stress Disorder
Petrakis IL, Poling J, Levinson C, Nich C, Carroll K, Ralevski E, Rounsaville B. Naltrexone and Disulfiram in Patients with Alcohol Dependence and Comorbid Post-Traumatic Stress Disorder. Biological Psychiatry 2006, 60: 777-783. PMID: 17008146, DOI: 10.1016/j.biopsych.2006.03.074.Peer-Reviewed Original ResearchConceptsPost-traumatic stress disorderAlcohol dependencePsychiatric symptomsComorbid post-traumatic stress disorderVeterans Administration Outpatient ClinicStress disorderAxis I psychiatric disordersBetter alcohol outcomesDouble-blind randomizationOverall psychiatric symptomsDSM-IV criteriaTreatment of alcoholismOpen randomizationActive medicationAdverse eventsAlcohol use outcomesOutpatient clinicGGT levelsMedication studiesPsychiatric disordersSide effectsNaltrexoneAlcohol cravingDrug AdministrationPlacebo
2004
Prize reinforcement contingency management for treating cocaine users: how low can we go, and with whom?
Petry NM, Tedford J, Austin M, Nich C, Carroll KM, Rounsaville BJ. Prize reinforcement contingency management for treating cocaine users: how low can we go, and with whom? Addiction 2004, 99: 349-360. PMID: 14982548, PMCID: PMC3709247, DOI: 10.1111/j.1360-0443.2003.00642.x.Peer-Reviewed Original ResearchConceptsStandard treatmentUrinalysis resultsNegative urinalysis resultsCM conditionCommunity-based treatment centersPositive urinalysis resultsCommunity-based settingsContingency management interventionSevere patientsNegative urine samplesTreatment periodCM interventionPatientsTreatment centersMore abstinenceDrug useCocaine useTreatment assignmentBeneficial effectsUrine samplesCocaine usersContingency managementTreatmentInterventionGoal-related activitiesEthnic Differences in Substance Abuse Treatment Retention, Compliance, and Outcome From Two Clinical Trials
Milligan CO, Nich C, Carroll KM. Ethnic Differences in Substance Abuse Treatment Retention, Compliance, and Outcome From Two Clinical Trials. Psychiatric Services 2004, 55: 167-173. PMID: 14762242, PMCID: PMC3666311, DOI: 10.1176/appi.ps.55.2.167.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnalysis of VarianceAntidepressive Agents, TricyclicBlack PeopleCocaine-Related DisordersCognitive Behavioral TherapyCombined Modality TherapyConnecticutDesipramineDisulfiramEnzyme InhibitorsFemaleHumansMalePatient CompliancePatient DropoutsRetrospective StudiesTreatment OutcomeWhite PeopleConceptsCocaine use outcomesTreatment expectationsTreatment retentionAfrican AmericansUse outcomesExpectations of treatmentSubstance abuse treatment retentionDays of treatmentDifferent behavioral treatmentsClinical trialsPretreatment characteristicsAfrican American participantsMedication componentsCocaine dependence
1997
Now You See It, Now You Don't: A Comparison of Traditional Versus Random-Effects Regression Models in the Analysis of Longitudinal Follow-Up Data From a Clinical Trial
Nich C, Carroll K. Now You See It, Now You Don't: A Comparison of Traditional Versus Random-Effects Regression Models in the Analysis of Longitudinal Follow-Up Data From a Clinical Trial. Journal Of Consulting And Clinical Psychology 1997, 65: 252-261. PMID: 9086688, DOI: 10.1037/0022-006x.65.2.252.Peer-Reviewed Original Research
1994
Psychotherapy and Pharmacotherapy for Ambulatory Cocaine Abusers
Carroll KM, Rounsaville BJ, Gordon LT, Nich C, Jatlow P, Bisighini RM, Gawin FH. Psychotherapy and Pharmacotherapy for Ambulatory Cocaine Abusers. JAMA Psychiatry 1994, 51: 177-187. PMID: 8122955, DOI: 10.1001/archpsyc.1994.03950030013002.Peer-Reviewed Original ResearchConceptsClinical managementCocaine useCocaine abusersRelapse preventionAmbulatory cocaine abusersWeeks of treatmentForm of treatmentHigh-severity patientsInitiation trialsAbstinence initiationBaseline severityClinical trialsEffective treatmentTreatment retentionBetter outcomesCocaine abusePharmacotherapyDepressed subjectsPlaceboDesipramine hydrochlorideSpecialized treatmentDesipraminePreventionGreater reductionDistinct subgroups