2021
A pilot economic evaluation of computerized cognitive behavioral therapy for alcohol use disorder as an addition and alternative to traditional therapy
Kacmarek CN, Yates BT, Nich C, Kiluk BD. A pilot economic evaluation of computerized cognitive behavioral therapy for alcohol use disorder as an addition and alternative to traditional therapy. Alcohol Clinical And Experimental Research 2021, 45: 1109-1121. PMID: 33730384, PMCID: PMC8131237, DOI: 10.1111/acer.14601.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcoholismAmbulatory CareCognitive Behavioral TherapyCost-Benefit AnalysisFemaleHealth ServicesHumansMaleMiddle AgedPilot ProjectsTherapy, Computer-AssistedTreatment OutcomeConceptsAlcohol use disorderIncremental cost-effective ratioCognitive behavioral therapyStandard outpatient treatmentPilot economic evaluationOutpatient treatmentTreatment costsUse disordersDrinking daysBehavioral therapyComputerized cognitive behavioral therapyEvidence-based treatmentsOutpatient treatment facilitiesTotal treatment costsCost of treatmentCost-effective ratioComputer-delivered interventionNet benefit analysisHealthcare utilizationCost-effective additionClinical trialsTreatment protocolCriminal justice involvementTraditional therapiesTreatment termination
2020
Short- and long-term changes in substance-related coping as mediators of in-person and computerized CBT for alcohol and drug use disorders
Roos CR, Carroll KM, Nich C, Frankforter T, Kiluk BD. Short- and long-term changes in substance-related coping as mediators of in-person and computerized CBT for alcohol and drug use disorders. Drug And Alcohol Dependence 2020, 212: 108044. PMID: 32422538, PMCID: PMC7293942, DOI: 10.1016/j.drugalcdep.2020.108044.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdultCognitive Behavioral TherapyFemaleHumansMaleMiddle AgedSubstance-Related DisordersTherapy, Computer-AssistedTime FactorsTreatment OutcomeConceptsCognitive behavioral therapyComputerized cognitive behavioral therapyPerson cognitive-behavioural therapySubstance use disordersMediation effectAlcohol use disorderComputer-delivered cognitive behavioural therapyUse disordersSame mediation effectSubstance-related copingCoping Strategies ScaleSignificant mediation effectMechanisms of changeMediational modelCoping skillsStrategies ScaleCBT4CBTStatistical mediatorCopingDrug use disordersSubstance useHeavy drinkingDisordersLong-term changesLong-term increase
2018
Randomized Clinical Trial of Computerized and Clinician-Delivered CBT in Comparison With Standard Outpatient Treatment for Substance Use Disorders: Primary Within-Treatment and Follow-Up Outcomes
Kiluk BD, Nich C, Buck MB, Devore KA, Frankforter TL, LaPaglia DM, Muvvala SB, Carroll KM. Randomized Clinical Trial of Computerized and Clinician-Delivered CBT in Comparison With Standard Outpatient Treatment for Substance Use Disorders: Primary Within-Treatment and Follow-Up Outcomes. American Journal Of Psychiatry 2018, 175: 853-863. PMID: 29792052, PMCID: PMC6120780, DOI: 10.1176/appi.ajp.2018.17090978.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmbulatory CareCognitive Behavioral TherapyFemaleFollow-Up StudiesHumansMaleSubstance-Related DisordersTherapy, Computer-AssistedTreatment OutcomeConceptsCognitive behavioral therapySubstance use disordersComputer-based cognitive behavioral therapyUse disordersMinimal clinical monitoringTreatment-seeking populationTreatment-seeking outpatientsDSM-IV-TR criteriaCBT groupFrequency of substanceStandard outpatient careCBT4CBTStand-alone treatmentDiverse sampleStandard outpatient treatmentCurrent substance use disorderBehavioral conceptsBetter learningSubstance abuseHeterogeneous sampleUp OutcomesHigh dropout ratePrevious trialsSix-month followClinical trials
2017
Drug Stroop: Mechanisms of response to computerized cognitive behavioral therapy for cocaine dependence in a randomized clinical trial
DeVito EE, Kiluk BD, Nich C, Mouratidis M, Carroll KM. Drug Stroop: Mechanisms of response to computerized cognitive behavioral therapy for cocaine dependence in a randomized clinical trial. Drug And Alcohol Dependence 2017, 183: 162-168. PMID: 29258028, PMCID: PMC5803332, DOI: 10.1016/j.drugalcdep.2017.10.022.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyDrug-related stimuliAttentional biasDrug-related cuesCognitive controlStroop effectStroop taskBehavioral therapyTreatment componentsComputer-based cognitive behavioral therapyComputerized cognitive behavioral therapyPoor cognitive controlCognitive control processesExecutive cognitive controlSubstance use severityCocaine use outcomesCocaine use disorderResponse inhibitionUse severityUse outcomesControl processGreater engagementTreatment retentionCBT4CBTCocaine dependenceEffect of computerized cognitive behavioral therapy on acquisition of coping skills among cocaine-dependent individuals enrolled in methadone maintenance
Kiluk BD, DeVito EE, Buck MB, Hunkele K, Nich C, Carroll KM. Effect of computerized cognitive behavioral therapy on acquisition of coping skills among cocaine-dependent individuals enrolled in methadone maintenance. Journal Of Substance Use And Addiction Treatment 2017, 82: 87-92. PMID: 29021121, PMCID: PMC5687291, DOI: 10.1016/j.jsat.2017.09.011.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdultCocaine-Related DisordersCognitive Behavioral TherapyFemaleHumansMaleMethadoneTherapy, Computer-AssistedConceptsCognitive behavioral therapyCocaine-dependent individualsHigh-risk situationsBehavioral therapyVerbal responsesComputerized cognitive behavioral therapyAbstinence outcomesComputerized CBT programParticipants' verbal responsesRole-play assessmentComputer-based trainingCertain high-risk situationsStandard methadone treatmentSubstance use disordersConsistent statistical supportCBT programMethadone treatmentMethadone maintenanceDependent individualsPlay assessmentPrior findingsClinical trialsTreatment periodUse disordersSubstance users
2016
Randomized Trial of Computerized Cognitive Behavioral Therapy for Alcohol Use Disorders: Efficacy as a Virtual Stand‐Alone and Treatment Add‐On Compared with Standard Outpatient Treatment
Kiluk BD, Devore KA, Buck MB, Nich C, Frankforter TL, LaPaglia DM, Yates BT, Gordon MA, Carroll KM. Randomized Trial of Computerized Cognitive Behavioral Therapy for Alcohol Use Disorders: Efficacy as a Virtual Stand‐Alone and Treatment Add‐On Compared with Standard Outpatient Treatment. Alcohol Clinical And Experimental Research 2016, 40: 1991-2000. PMID: 27488212, PMCID: PMC5008977, DOI: 10.1111/acer.13162.Peer-Reviewed Original ResearchConceptsAlcohol use disorderCognitive behavioral therapyComputerized cognitive behavioral therapyAlcohol useUse disordersClinical monitoringBehavioral therapyCurrent alcohol use disorderStandard outpatient treatmentEvidence-based treatmentsWeb-based CBT programPercentage of daysRandomized trialsPreliminary efficacyStandard treatmentOutpatient treatmentTreatment completionTreatment periodOutpatient facilitiesParticipants' alcohol useClinical practiceCBT4CBTCBT programTreatment-seeking individualsClinical samples
2015
Alexithymia level and response to computer-based training in cognitive behavioral therapy among cocaine-dependent methadone maintained individuals
Morie KP, Nich C, Hunkele K, Potenza MN, Carroll KM. Alexithymia level and response to computer-based training in cognitive behavioral therapy among cocaine-dependent methadone maintained individuals. Drug And Alcohol Dependence 2015, 152: 157-163. PMID: 25982006, PMCID: PMC4458169, DOI: 10.1016/j.drugalcdep.2015.04.004.Peer-Reviewed Original Research
2014
Only connect: The working alliance in computer-based cognitive behavioral therapy
Kiluk BD, Serafini K, Frankforter T, Nich C, Carroll KM. Only connect: The working alliance in computer-based cognitive behavioral therapy. Behaviour Research And Therapy 2014, 63: 139-146. PMID: 25461789, PMCID: PMC4408209, DOI: 10.1016/j.brat.2014.10.003.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyTechnology-based interventionsWorking Alliance InventoryBehavioral therapyComputer-based cognitive behavioral therapyCocaine-dependent individualsCocaine use outcomesEfficacy of computerDays abstinentFace psychotherapyUse outcomesSimilar psychometric characteristicsPsychometric characteristicsSubscale scoresAlliance InventoryTherapistsPreliminary findingsTotal scoreInterventionTreatment outcomesCBTScoresAbstinentPsychotherapyLittle evidenceComputer-Assisted Delivery of Cognitive-Behavioral Therapy: Efficacy and Durability of CBT4CBT Among Cocaine-Dependent Individuals Maintained on Methadone
Carroll KM, Kiluk BD, Nich C, Gordon MA, Portnoy GA, Marino DR, Ball SA. Computer-Assisted Delivery of Cognitive-Behavioral Therapy: Efficacy and Durability of CBT4CBT Among Cocaine-Dependent Individuals Maintained on Methadone. American Journal Of Psychiatry 2014, 171: 436-444. PMID: 24577287, PMCID: PMC4042674, DOI: 10.1176/appi.ajp.2013.13070987.Peer-Reviewed Original ResearchMeSH KeywordsAdultCocaine-Related DisordersCognitive Behavioral TherapyCombined Modality TherapyFemaleHumansMaleMethadoneMiddle AgedNarcoticsTherapy, Computer-AssistedTreatment OutcomeConceptsCocaine-dependent individualsCognitive behavioral therapyMethadone maintenanceCommunity-based outpatient clinicsPrevious pilot trialMethadone maintenance programStandard methadone maintenanceDisseminable strategyDefinitive trialOutpatient clinicClinical trialsEffective adjunctPilot trialTreatment terminationTreatment retentionBetter outcomesConsecutive weeksCBT4CBTWeekly accessAddiction treatmentDurable effectsTrialsSubstance usersStatistical significanceMethadone
2011
A Methodological Analysis of Randomized Clinical Trials of Computer-Assisted Therapies for Psychiatric Disorders: Toward Improved Standards for an Emerging Field
Kiluk BD, Sugarman DE, Nich C, Gibbons CJ, Martino S, Rounsaville BJ, Carroll KM. A Methodological Analysis of Randomized Clinical Trials of Computer-Assisted Therapies for Psychiatric Disorders: Toward Improved Standards for an Emerging Field. American Journal Of Psychiatry 2011, 168: 790-799. PMID: 21536689, PMCID: PMC3607199, DOI: 10.1176/appi.ajp.2011.10101443.Peer-Reviewed Original ResearchMeSH KeywordsAdultEvidence-Based MedicineHumansMental DisordersPsychotherapyRandomized Controlled Trials as TopicReference StandardsTherapy, Computer-AssistedTreatment OutcomeUnited StatesConceptsComputer-assisted therapyRandomized clinical trialsPsychiatric disordersClinical trialsMethodological qualityEvidence-based behavioral therapiesMethodological Quality IndexPotential adverse eventsEvidence-based therapiesAxis I DisordersAdult psychiatric disordersMethodological quality scoreEvidence-based interventionsAdverse eventsTreat principleRandomized trialsI disordersStudy qualityTreatment exposureTherapyBehavioral therapyCost-effective strategyDisordersTrialsCurrent standard
2010
Coping Strategy Use Following Computerized Cognitive-Behavioral Therapy for Substance Use Disorders
Sugarman DE, Nich C, Carroll KM. Coping Strategy Use Following Computerized Cognitive-Behavioral Therapy for Substance Use Disorders. Psychology Of Addictive Behaviors 2010, 24: 689-695. PMID: 21198228, PMCID: PMC3059590, DOI: 10.1037/a0021584.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdultCognitive Behavioral TherapyFemaleHumansMaleMiddle AgedSubstance-Related DisordersTherapy, Computer-AssistedTreatment OutcomeConceptsCognitive behavioral therapyStrategy useObserver ratingsComputerized cognitive behavioral therapyCoping Strategy UseOutpatient substance abuse treatment facilitiesSubstance abuse treatment facilitiesCoping Strategies ScaleRole-play assessmentComputer-based versionSignificant group differencesSubstance use disordersCoping strategiesStrategies ScaleGroup differencesSubstance usersSubstance dependenceUse disordersCBT4CBTDifferential effectsSkillsDrug useDrug-related outcomesParticipantsRatingsRelationship of cognitive function and the acquisition of coping skills in computer assisted treatment for substance use disorders
Kiluk BD, Nich C, Carroll KM. Relationship of cognitive function and the acquisition of coping skills in computer assisted treatment for substance use disorders. Drug And Alcohol Dependence 2010, 114: 169-176. PMID: 21050679, PMCID: PMC3046302, DOI: 10.1016/j.drugalcdep.2010.09.019.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdultCognitionCognitive Behavioral TherapyFemaleHumansMaleSubstance-Related DisordersTherapy, Computer-AssistedTreatment OutcomeConceptsCognitive behavioral therapyCognitive functioningCoping skillsBehavioral therapySubstance useCoping skills trainingMeasures of IQSubstance-dependent individualsSignificant indirect effectSubstance use outcomesChronic substance useNeuropsychological measuresNeuropsychological factorsSubstance use disordersComputerized versionHigher IQSkills trainingCognitive functionLower IQLittle previous researchIQDependent individualsPoor functioningUse outcomesCognitive impairmentQuality versus quantity: acquisition of coping skills following computerized cognitive–behavioral therapy for substance use disorders
Kiluk BD, Nich C, Babuscio T, Carroll KM. Quality versus quantity: acquisition of coping skills following computerized cognitive–behavioral therapy for substance use disorders. Addiction 2010, 105: 2120-2127. PMID: 20854334, PMCID: PMC2975828, DOI: 10.1111/j.1360-0443.2010.03076.x.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyComputerized CBT programEffects of CBTComputerized cognitive behavioral therapySubstance use disordersEffect of treatmentSubstance use outcomesRole-play taskTreatment completionHigh riskPrimary drugUse disordersAverage ageCommunity settingsBehavioral therapyPatient treatmentSubstance dependenceAlcohol useCBT programSubstance useUse outcomesComputerized versionParticipants' durationSignificant increaseTreatment
2008
Enduring effects of a computer-assisted training program for cognitive behavioral therapy: A 6-month follow-up of CBT4CBT
Carroll KM, Ball SA, Martino S, Nich C, Babuscio TA, Rounsaville BJ. Enduring effects of a computer-assisted training program for cognitive behavioral therapy: A 6-month follow-up of CBT4CBT. Drug And Alcohol Dependence 2008, 100: 178-181. PMID: 19041197, PMCID: PMC2742309, DOI: 10.1016/j.drugalcdep.2008.09.015.Peer-Reviewed Original ResearchMeSH KeywordsAmbulatory CareCognitive Behavioral TherapyFemaleFollow-Up StudiesHumansMaleSubstance-Related DisordersTherapy, Computer-AssistedTime FactorsTreatment OutcomeConceptsCognitive behavioral therapyBehavioral therapyComputer-assisted training programSubstance dependenceComputer-based trainingSubstance use outcomesComputer-assisted versionDrug useEnduring effectCBT4CBTUse outcomesRandomized clinical trialsTreatment retentionDurability of effectTraining programOutpatient communityStudy treatmentStandard treatmentOutpatient treatmentClinical trialsTreatment conditionsParticipantsSignificant differencesTreatmentRegression analysisComputer-Assisted Delivery of Cognitive-Behavioral Therapy for Addiction: A Randomized Trial of CBT4CBT
Carroll KM, Ball SA, Martino S, Nich C, Babuscio TA, Nuro KF, Gordon MA, Portnoy GA, Rounsaville BJ. Computer-Assisted Delivery of Cognitive-Behavioral Therapy for Addiction: A Randomized Trial of CBT4CBT. American Journal Of Psychiatry 2008, 165: 881-888. PMID: 18450927, PMCID: PMC2562873, DOI: 10.1176/appi.ajp.2008.07111835.Peer-Reviewed Original Research