2000
Adverse Life Events and Cognitive-Personality Characteristics in the Prediction of Major Depression and Antidepressant Response
Mazure CM, Bruce ML, Maciejewski PK, Jacobs SC. Adverse Life Events and Cognitive-Personality Characteristics in the Prediction of Major Depression and Antidepressant Response. American Journal Of Psychiatry 2000, 157: 896-903. PMID: 10831468, DOI: 10.1176/appi.ajp.157.6.896.Peer-Reviewed Original ResearchConceptsCognitive-personality stylesCognitive–personality characteristicsAdverse life eventsStressful life eventsMajor depressionLife eventsTreatment outcomesComparison subjectsDepressive onsetMultivariate modelCommunity comparison subjectsDSM-IV unipolar depressionDepressive symptom severityHealthy comparison subjectsEvent typesAntidepressant regimenAdverse eventsAntidepressant responseInterpersonal eventsAchievement eventsUnipolar depressionBetter outcomesEpisode onsetSymptom severityGroup status
1999
Childhood Sexual Abuse as a Risk Factor for Depression in Women: Psychosocial and Neurobiological Correlates
Weiss EL, Longhurst JG, Mazure CM. Childhood Sexual Abuse as a Risk Factor for Depression in Women: Psychosocial and Neurobiological Correlates. American Journal Of Psychiatry 1999, 156: 816-828. PMID: 10360118, DOI: 10.1176/ajp.156.6.816.Peer-Reviewed Original ResearchConceptsAdult-onset depressionChildhood sexual abuseEarly stressorsHPA axisSexual abuseAdrenal axis functionLong-term dysregulationMajor depressive disorderStress-induced dysregulationDepressive illnessAxis functionDepressed patientsDepressive disorderRisk factorsLong-term effectsHuman studiesManual searchNeurobiological correlatesPsychosocial mechanismsDepressionWomenEarly stressDysregulationSubsequent developmentDysregulation results