2001
Clozapine in the treatment of aggression in an adolescent with autistic disorder.
Chen N, Bedair H, McKay B, Bowers M, Mazure C. Clozapine in the treatment of aggression in an adolescent with autistic disorder. The Journal Of Clinical Psychiatry 2001, 62: 479-80. PMID: 11465533, DOI: 10.4088/jcp.v62n0612h.Peer-Reviewed Original Research
1999
Olanzapine for Treatment-Refractory Psychosis in Patients Responsive to, but Intolerant of, Clozapine
Weiss E, Longhurst J, Bowers M, Mazure C. Olanzapine for Treatment-Refractory Psychosis in Patients Responsive to, but Intolerant of, Clozapine. Journal Of Clinical Psychopharmacology 1999, 19: 378-380.. PMID: 10440469, DOI: 10.1097/00004714-199908000-00017.Peer-Reviewed Original Research
1998
Management of the Adverse Effects of Clozapine
Young CR, Bowers MB, Mazure CM. Management of the Adverse Effects of Clozapine. Schizophrenia Bulletin 1998, 24: 381-390. PMID: 9718630, DOI: 10.1093/oxfordjournals.schbul.a033333.Peer-Reviewed Original ResearchConceptsAdverse effectsElevated liver enzymesPercent of patientsSuccessful pharmacological managementPositive therapeutic outcomesHypothesized pathophysiologyPharmacological managementRefractory schizophreniaNeuromuscular effectsTraditional neurolepticsLiver enzymesPharmacological interventionsClozapineAffective disordersTherapeutic outcomesNeurological disordersMental disordersMaximum doseObsessive-compulsive symptomsWeight gainDisordersPatientsPathophysiologyNew hopeTreatment
1997
The Expanding Indications for Clozapine
Young C, Longhurst J, Bowers M, Mazure C. The Expanding Indications for Clozapine. Experimental And Clinical Psychopharmacology 1997, 5: 216-234. PMID: 9260069, DOI: 10.1037/1064-1297.5.3.216.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntipsychotic AgentsClozapineHumansMood DisordersNervous System DiseasesSchizophreniaConceptsUnique pharmacodynamic profileUse of clozapineTreatment-resistant schizophreniaTraditional drug treatmentExpanding IndicationsClozapine treatmentNeurologic conditionsPharmacodynamic profileClinical indicationsDrug treatmentMood disordersEffective treatmentClozapineSubstance abuseChildhood schizophreniaRelevant literatureSchizophreniaDisordersTreatmentAggressive behaviorIndicationsInitial rationaleAgranulocytosisPatientsBody of literature