1995
Assessment of extrapyramidal symptoms during acute neuroleptic treatment.
Mazure CM, Cellar JS, Bowers MB, Nelson JC, Takeshita J, Zigun B. Assessment of extrapyramidal symptoms during acute neuroleptic treatment. The Journal Of Clinical Psychiatry 1995, 56: 94-100. PMID: 7883736.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdultAkathisia, Drug-InducedAntipsychotic AgentsBasal Ganglia DiseasesDystoniaFemaleHumansMaleMiddle AgedParkinson Disease, SecondaryPhysical ExaminationPsychiatric Status Rating ScalesPsychotic DisordersReproducibility of ResultsSeverity of Illness IndexStatistics, NonparametricConceptsExtrapyramidal symptomsDrug regimenAcute treatmentNeuroleptic drugsSide effectsInterrater reliabilityAcute neuroleptic treatmentPatient's drug regimenExtrapyramidal Symptoms ScaleExtrapyramidal side effectsTraditional neuroleptic drugsLow nonsignificant correlationsRatings of symptomsAcute administrationNeuroleptic treatmentAdverse reactionsParkinson's diseasePsychotic symptomsSymptom ScalePsychotic patientsEPS scaleSymptomsClinician ratersCliniciansInterrater agreement
1990
The relationship between blood perphenazine levels, early resolution of psychotic symptoms, and side effects.
Mazure CM, Nelson JC, Jatlow PI, Kincare P, Bowers MB. The relationship between blood perphenazine levels, early resolution of psychotic symptoms, and side effects. The Journal Of Clinical Psychiatry 1990, 51: 330-4. PMID: 2199431.Peer-Reviewed Original ResearchMeSH KeywordsAdultAkathisia, Drug-InducedBasal Ganglia DiseasesBenztropineClinical Trials as TopicDose-Response Relationship, DrugDrug Administration ScheduleFemaleHospitalizationHumansMaleParkinson Disease, SecondaryPerphenazinePsychiatric Status Rating ScalesPsychotic DisordersSchizophreniaSchizophrenic PsychologyConceptsExtrapyramidal side effectsSide effectsBrief Psychiatric Rating Scale (BPRS) totalSerious extrapyramidal side effectsIndividual BPRS itemsResolution of psychosisEarly resolutionBlood level monitoringBlood levelsIndividual symptomsTherapeutic thresholdPsychotic symptomsPsychotic inpatientsScale totalDrug efficacyBPRS itemsPerphenazine concentrationSymptomsPsychosisPerphenazineLevel monitoring