Characteristics of desipramine-refractory depression.
Nelson JC, Mazure CM, Jatlow PI. Characteristics of desipramine-refractory depression. The Journal Of Clinical Psychiatry 1994, 55: 12-9. PMID: 8294386.Peer-Reviewed Original ResearchConceptsDepressive episodePoor responseMajor depressionNonpsychotic unipolar major depressionPrior treatment failureAdequate blood levelsWeeks of hospitalizationDrug responseUnipolar major depressionRecurrence of depressionDefinite personality disorderDiagnosis of melancholiaConsecutive inpatientsDesipramine levelsTreatment failureBlood levelsGeneral HospitalInitial severityPlasma concentrationsDrug treatmentSecondary depressionDepression InventoryPatientsPersonality disorderDepression