2024
Researching COVID to enhance recovery (RECOVER) pediatric study protocol: Rationale, objectives and design
Gross R, Thaweethai T, Rosenzweig E, Chan J, Chibnik L, Cicek M, Elliott A, Flaherman V, Foulkes A, Witvliet M, Gallagher R, Gennaro M, Jernigan T, Karlson E, Katz S, Kinser P, Kleinman L, Lamendola-Essel M, Milner J, Mohandas S, Mudumbi P, Newburger J, Rhee K, Salisbury A, Snowden J, Stein C, Stockwell M, Tantisira K, Thomason M, Truong D, Warburton D, Wood J, Ahmed S, Akerlundh A, Alshawabkeh A, Anderson B, Aschner J, Atz A, Aupperle R, Baker F, Balaraman V, Banerjee D, Barch D, Baskin-Sommers A, Bhuiyan, Bind M, Bogie A, Bradford T, Buchbinder N, Bueler E, Bükülmez H, Casey B, Chang L, Chrisant M, Clark D, Clifton R, Clouser K, Cottrell L, Cowan K, D’Sa V, Dapretto M, Dasgupta S, Dehority W, Dionne A, Dummer K, Elias M, Esquenazi-Karonika S, Evans D, Faustino E, Fiks A, Forsha D, Foxe J, Friedman N, Fry G, Gaur S, Gee D, Gray K, Handler S, Harahsheh A, Hasbani K, Heath A, Hebson C, Heitzeg M, Hester C, Hill S, Hobart-Porter L, Hong T, Horowitz C, Hsia D, Huentelman M, Hummel K, Irby K, Jacobus J, Jacoby V, Jone P, Kaelber D, Kasmarcak T, Kluko M, Kosut J, Laird A, Landeo-Gutierrez J, Lang S, Larson C, Lim P, Lisdahl K, McCrindle B, McCulloh R, McHugh K, Mendelsohn A, Metz T, Miller J, Mitchell E, Morgan L, Müller-Oehring E, Nahin E, Neale M, Ness-Cochinwala M, Nolan S, Oliveira C, Osakwe O, Oster M, Payne R, Portman M, Raissy H, Randall I, Rao S, Reeder H, Rosas J, Russell M, Sabati A, Sanil Y, Sato A, Schechter M, Selvarangan R, Tejtel S, Shakti D, Sharma K, Squeglia L, Srivastava S, Stevenson M, Szmuszkovicz J, Talavera-Barber M, Teufel R, Thacker D, Trachtenberg F, Udosen M, Warner M, Watson S, Werzberger A, Weyer J, Wood M, Yin H, Zempsky W, Zimmerman E, Dreyer B, Consortium O. Researching COVID to enhance recovery (RECOVER) pediatric study protocol: Rationale, objectives and design. PLOS ONE 2024, 19: e0285635. PMID: 38713673, PMCID: PMC11075869, DOI: 10.1371/journal.pone.0285635.Peer-Reviewed Original ResearchConceptsYoung adultsClinical courseAdolescent Brain Cognitive DevelopmentCaregiver-child pairsLong-term outcomesObservational cohort studyOutcomes of COVID-19De novo cohortAdolescent Brain Cognitive Development StudySociodemographic correlatesCommunity partnersBaseline assessmentLongitudinal follow-upPotential therapeutic interventionsPediatric protocolsCohort studyCollaborative partnershipsProspective cohortFollow-upStudy protocolFederal partnersNIH Researching COVIDLong-term outcomes of COVID-19Enhanced recoveryData collection
2022
Assessment of Clinical Effectiveness of BNT162b2 COVID-19 Vaccine in US Adolescents
Oliveira CR, Niccolai LM, Sheikha H, Elmansy L, Kalinich CC, Grubaugh ND, Shapiro ED, Billig K, Breban M, Brito A, Earnest R, Fauver J, Koch T, Ott I, Petrone M, Vogels C, Pham K, Tikhonova I, Castaldi C, Mane S, Bilguvar K, De Kumar B, Ferguson D, Kerantzas N, Landry M, Peaper D, Schulz W. Assessment of Clinical Effectiveness of BNT162b2 COVID-19 Vaccine in US Adolescents. JAMA Network Open 2022, 5: e220935. PMID: 35238933, PMCID: PMC8895259, DOI: 10.1001/jamanetworkopen.2022.0935.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 infectionCase-control studyVaccine effectivenessBNT162b2 vaccineSARS-CoV-2Medical recordsAsymptomatic SARS-CoV-2 infectionBNT162b2 COVID-19 vaccineRetrospective case-control studyRT-PCR test resultsSARS-CoV-2 testUS adolescentsReverse transcription polymerase chain reaction testConditional logistic regression modelsTranscription polymerase chain reaction testDoses of vaccineControl participantsClinical trial populationsRelevant clinical dataCase participantsCOVID-19 vaccinePositive test resultsChain reaction testCounty of residenceNegative test results
2021
Initial Guidance on Use of Monoclonal Antibody Therapy for Treatment of Coronavirus Disease 2019 in Children and Adolescents
Wolf J, Abzug MJ, Wattier RL, Sue PK, Vora SB, Zachariah P, Dulek DE, Waghmare A, Olivero R, Downes KJ, James SH, Pinninti SG, Yarbrough A, Aldrich ML, MacBrayne CE, Soma VL, Grapentine SP, Oliveira CR, Hayes M, Kimberlin DW, Jones SB, Bio LL, Morton TH, Hankins JS, Marόn-Alfaro G, Timberlake K, Young JL, Orscheln RC, Schwenk HT, Goldman DL, Groves HE, Huskins WC, Rajapakse NS, Lamb GS, Tribble AC, Lloyd E, Hersh AL, Thorell EA, Ratner AJ, Chiotos K, Nakamura MM. Initial Guidance on Use of Monoclonal Antibody Therapy for Treatment of Coronavirus Disease 2019 in Children and Adolescents. Journal Of The Pediatric Infectious Diseases Society 2021, 10: 629-634. PMID: 33388760, PMCID: PMC7799019, DOI: 10.1093/jpids/piaa175.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsMonoclonal antibody therapyHigh-risk groupAntibody therapyEmergency use authorizationCOVID-19Moderate coronavirus disease 2019Pediatric intensive care medicinePediatric-specific evidenceTreatment of mildPediatric infectious diseasesHigh-quality evidenceCoronavirus disease 2019Intensive care medicineSeries of teleconferencesREGN-COV2Infusion reactionsPediatric HematologyTimely administrationRisk factorsRoutine administrationDisease 2019Severe diseaseCare medicineHigh riskModest benefit
2020
Severe Acute Respiratory Syndrome Coronavirus 2 Testing in Children in a Large Regional US Health System During the Coronavirus Disease 2019 Pandemic.
Peaper DR, Murdzek C, Oliveira CR, Murray TS. Severe Acute Respiratory Syndrome Coronavirus 2 Testing in Children in a Large Regional US Health System During the Coronavirus Disease 2019 Pandemic. The Pediatric Infectious Disease Journal 2020, 40: 175-181. PMID: 33399431, PMCID: PMC8852689, DOI: 10.1097/inf.0000000000003024.Peer-Reviewed Original ResearchConceptsYale New Haven Health SystemSevere acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2Respiratory syndrome coronavirus 2Syndrome coronavirus 2Subset of childrenPediatric casesHealth systemCycle threshold valuesCoronavirus 2Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNACross-sectional time-series studyCoronavirus disease 2019 (COVID-19) testingPositive pediatric casesSimilar cycle threshold valuesCoronavirus disease 2019 (COVID-19) pandemicUpper respiratory tractCoronavirus disease 2019Large health systemYears of ageDisease 2019 pandemicUS health systemAmbulatory locationsVirology resultsAsymptomatic childrenSevere Acute Respiratory Syndrome Coronavirus 2 Clinical Syndromes and Predictors of Disease Severity in Hospitalized Children and Youth
Fernandes DM, Oliveira CR, Guerguis S, Eisenberg R, Choi J, Kim M, Abdelhemid A, Agha R, Agarwal S, Aschner JL, Avner JR, Ballance C, Bock J, Bhavsar SM, Campbell M, Clouser KN, Gesner M, Goldman DL, Hammerschlag MR, Hymes S, Howard A, Jung HJ, Kohlhoff S, Kojaoghlanian T, Lewis R, Nachman S, Naganathan S, Paintsil E, Pall H, Sy S, Wadowski S, Zirinsky E, Cabana MD, Herold BC, Consortium T. Severe Acute Respiratory Syndrome Coronavirus 2 Clinical Syndromes and Predictors of Disease Severity in Hospitalized Children and Youth. The Journal Of Pediatrics 2020, 230: 23-31.e10. PMID: 33197493, PMCID: PMC7666535, DOI: 10.1016/j.jpeds.2020.11.016.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBiomarkersChildChild, PreschoolConnecticutCOVID-19C-Reactive ProteinFemaleHospitalizationHumansHypoxiaInfantIntensive Care UnitsLymphocyte CountMaleMultivariate AnalysisNew JerseyNew YorkPediatric ObesityProcalcitoninProspective StudiesRetrospective StudiesSeverity of Illness IndexSystemic Inflammatory Response SyndromeTroponinYoung AdultConceptsSARS-CoV-2 infectionRespiratory diseaseDisease severityClinical featuresAcute SARS-CoV-2 infectionGreater C-reactive proteinLow absolute lymphocyte countFuture prognostic toolAbsolute lymphocyte countTime of hospitalizationC-reactive proteinIntensive care unitSevere respiratory diseaseNon-Hispanic blacksRace/ethnicitySevere MISInflammatory syndromeLymphocyte countHospital admissionPediatric patientsCare unitMultivariable analysisProspective studyHospitalized childrenClinical managementTrends in Anogenital Wart Diagnoses in Connecticut, 2013-2017
Yakely AE, Niccolai LM, Oliveira CR. Trends in Anogenital Wart Diagnoses in Connecticut, 2013-2017. JAMA Network Open 2020, 3: e1920168. PMID: 32003814, PMCID: PMC7042856, DOI: 10.1001/jamanetworkopen.2019.20168.Peer-Reviewed Original Research
2019
Human papillomavirus vaccination and anogenital warts
Yakely AE, Avni-Singer L, Oliveira CR, Niccolai LM. Human papillomavirus vaccination and anogenital warts. Sexually Transmitted Diseases 2019, Publish Ahead of Print: &na;. PMID: 30461595, PMCID: PMC6640846, DOI: 10.1097/olq.0000000000000948.Peer-Reviewed Original ResearchConceptsAnogenital wartsAge 25 yearsHPV vaccineEffectiveness studiesHPV vaccine impactHuman papillomavirus vaccinationPre-vaccine eraMale vaccinationPapillomavirus vaccinationVaccination historyVaccine impactVaccine introductionFemale vaccinationEmbase databasesVaccination programEligible studiesExclusion criteriaLower riskVaccineVaccinationWartsPrevention potentialReal-world benefitsFemalesUnited States
2016
Influenza-like illness in an urban community of Salvador, Brazil: incidence, seasonality and risk factors
Oliveira CR, Costa GSR, Paploski IAD, Kikuti M, Kasper AM, Silva MMO, Tavares AS, Cruz JS, Queiroz TL, Lima HCAV, Calcagno J, Reis MG, Weinberger DM, Shapiro ED, Ko AI, Ribeiro GS. Influenza-like illness in an urban community of Salvador, Brazil: incidence, seasonality and risk factors. BMC Infectious Diseases 2016, 16: 125. PMID: 26975185, PMCID: PMC4791800, DOI: 10.1186/s12879-016-1456-8.Peer-Reviewed Original ResearchConceptsInfluenza-like illnessYears of ageAcute febrile illnessAnnual incidenceRisk of ILIChildren 5Year oldsIncidence of ILIMean annual incidenceEpidemiology of influenzaCommunity-based surveillanceNegative test resultsSeasonal influenza transmissionILI peakMethodsBetween 2009Febrile illnessSore throatRegression modelsDisease burdenRisk factorsSchool-aged childrenEmergency unitInfluenza transmissionSignificant burdenYoung school-age children
2014
Complications of Vaccination With Bacille Calmette-Guérin
Oliveira CR, Baltimore RS. Complications of Vaccination With Bacille Calmette-Guérin. Clinical Pediatrics 2014, 53: 914-916. PMID: 24807981, PMCID: PMC6848971, DOI: 10.1177/0009922814533414.Peer-Reviewed Case Reports and Technical NotesBrain Magnetic Resonance Imaging of Infants with Bacterial Meningitis
Oliveira CR, Morriss MC, Mistrot JG, Cantey JB, Doern CD, Sánchez PJ. Brain Magnetic Resonance Imaging of Infants with Bacterial Meningitis. The Journal Of Pediatrics 2014, 165: 134-139. PMID: 24726712, PMCID: PMC6855593, DOI: 10.1016/j.jpeds.2014.02.061.Peer-Reviewed Original ResearchConceptsBrain magnetic resonance imagingMagnetic resonance imagingBacterial meningitisPositive bacterial culturesCerebrospinal fluidClinical managementNeurosurgical interventionMedical CenterNormal brain magnetic resonance imagingCulture-confirmed bacterial meningitisPositive CSF culture resultsResonance imagingAbnormal magnetic resonance imagingMultiple logistic regression analysisAbnormal neurologic examinationCSF culture resultsChildren's Medical CenterLogistic regression analysisMonths of ageLate seizuresCerebral infarctsLeptomeningeal enhancementAntibiotic therapyCSF cultureNeurologic examination