Featured Publications
Health status and cognitive function for risk stratification in chronic coronary and peripheral artery disease.
Smolderen K, Mena-Hurtado C, Eikelboom J, Bosch J, Xie F, Ramasundarahettige C, Bhatt D, Anand S. Health status and cognitive function for risk stratification in chronic coronary and peripheral artery disease. European Journal Of Preventive Cardiology 2022, 30: 535-545. PMID: 36444513, DOI: 10.1093/eurjpc/zwac282.Peer-Reviewed Original ResearchMeSH KeywordsCognitionCoronary Artery DiseaseHealth StatusHumansPeripheral Arterial DiseaseRisk AssessmentRisk FactorsConceptsCoronary artery diseaseDigit Symbol Substitution TestVisual analog scaleEQ visual analogue scaleHealth statusLimb eventsCAD cohortCognitive functionArtery diseaseEQ-5DHierarchical Cox regression modelsMajor adverse cardiovascular eventsStable coronary artery diseaseAdverse cardiovascular eventsPeripheral artery diseasePopulation attributable riskCox regression modelOverall health statusCognitive function assessmentCOMPASS trialPAD cohortCardiovascular eventsPAD patientsRisk stratificationAnalog scale
2023
In-home Visits and Subsequent Health Outcomes in Medicare Advantage Beneficiaries With Coronary Artery Disease, Diabetes, Hypertension, and Depression
Smolderen K, Heath K, Ameli O, Spencer D, Natwick T, Musich S, Miedico T, Mena-Hurtado C. In-home Visits and Subsequent Health Outcomes in Medicare Advantage Beneficiaries With Coronary Artery Disease, Diabetes, Hypertension, and Depression. Medical Care 2023, 61: 366-376. PMID: 37167558, DOI: 10.1097/mlr.0000000000001850.Peer-Reviewed Original ResearchMeSH KeywordsAgedCoronary Artery DiseaseDepressionDiabetes MellitusHouse CallsHumansHypertensionMedicare Part COutcome Assessment, Health CareRetrospective StudiesUnited StatesConceptsPrimary care visitsCoronary artery diseaseMajor adverse cardiovascular eventsFirst primary care visitAdverse cardiovascular eventsCare visitsWait-list control groupHome visitsArtery diseaseList control groupControl groupCardiovascular eventsCare metricsOptum Labs Data WarehouseHigh-morbidity conditionsMedicare Advantage populationInpatient care episodesMedicare Advantage beneficiariesRetrospective data analysisSubsequent health outcomesIndex dateSecondary outcomesEmergency visitsPrimary outcomeInpatient stay
2022
The association of depression with mortality and major adverse limb event outcomes in patients with peripheral artery disease: A systematic review and meta-analysis
Scierka LE, Mena-Hurtado C, Ahmed ZV, Yousef S, Arham A, Grimshaw AA, Harris KM, Burg M, Vriens PW, Heyligers J, Lee M, Yazgan I, Smolderen KG. The association of depression with mortality and major adverse limb event outcomes in patients with peripheral artery disease: A systematic review and meta-analysis. Journal Of Affective Disorders 2022, 320: 169-177. PMID: 36179780, DOI: 10.1016/j.jad.2022.09.098.Peer-Reviewed Original ResearchMeSH KeywordsComorbidityCoronary Artery DiseaseDepressionHumansMalePeripheral Arterial DiseaseRisk FactorsConceptsMajor adverse limb eventsPeripheral artery diseaseAssociation of depressionCause mortalityArtery diseaseDepressive symptomsSystematic reviewAdverse limb eventsAdverse prognostic outcomeCoronary artery diseaseRisk of biasImportant comorbidityPoor outcomeAdverse outcomesPrognostic outcomesPooled resultsRisk factorsObservational studyTreatment statusLimb eventsDepression severityPatientsLarger sample sizeMortalityRisk estimates
2021
Principles of Intravascular Lithotripsy for Calcific Plaque Modification
Kereiakes DJ, Virmani R, Hokama JY, Illindala U, Mena-Hurtado C, Holden A, Hill JM, Lyden SP, Ali ZA. Principles of Intravascular Lithotripsy for Calcific Plaque Modification. JACC Cardiovascular Interventions 2021, 14: 1275-1292. PMID: 34167671, DOI: 10.1016/j.jcin.2021.03.036.Peer-Reviewed Original ResearchConceptsIntravascular lithotripsyPeri-procedural adverse eventsLower procedural success ratesProcedural success rateUnfavorable clinical outcomePeripheral vascular bedsCalcium fractureIVL useAdverse eventsClinical outcomesPlaque modificationLuminal gainTranscatheter interventionsPlaque lesionsCalcific plaquesPeripheral vasculatureVascular bedClinical dataCardiovascular therapyStent expansionSuccess rateLesionsSignificant proportionLithotripsy technologyPlaques
2020
Multivessel Versus Culprit-Only Revascularization in STEMI and Multivessel Coronary Artery Disease Meta-Analysis of Randomized Trials
Atti V, Gwon Y, Narayanan MA, Garcia S, Sandoval Y, Brilakis ES, Basir MB, Turagam MK, Khandelwal A, Mena-Hurtado C, Mamas MA, Abbott JD, Bhatt DL, Velagapudi P. Multivessel Versus Culprit-Only Revascularization in STEMI and Multivessel Coronary Artery Disease Meta-Analysis of Randomized Trials. JACC Cardiovascular Interventions 2020, 13: 1571-1582. PMID: 32646699, DOI: 10.1016/j.jcin.2020.04.055.Peer-Reviewed Original ResearchConceptsMultivessel percutaneous coronary interventionST-segment elevation myocardial infarctionPercutaneous coronary interventionElevation myocardial infarctionMultivessel coronary artery diseaseCulprit vesselCoronary artery diseaseCause mortalityMyocardial infarctionArtery diseaseControlled TrialsRisk ratioLower riskUnderwent multivessel PCIVersus Culprit-Only RevascularizationCulprit-only revascularizationMultivessel PCI strategyPrimary efficacy outcomeCochrane Central RegisterContrast-induced nephropathyConfidence intervalsRandom-effects modelWeb of ScienceMajor bleedingCardiovascular mortality
2013
The link between vasculogenic erectile dysfunction, coronary artery disease, and peripheral artery disease: role of metabolic factors and endovascular therapy.
Meller SM, Stilp E, Walker CN, Mena-Hurtado C. The link between vasculogenic erectile dysfunction, coronary artery disease, and peripheral artery disease: role of metabolic factors and endovascular therapy. Journal Of Invasive Cardiology 2013, 25: 313-9. PMID: 23735361.Peer-Reviewed Original ResearchConceptsPeripheral artery diseaseCoronary artery diseaseVasculogenic erectile dysfunctionErectile dysfunctionArtery diseaseEndovascular therapyMetabolic factorsPathophysiology of EDArtery size hypothesisIncident clinical eventsPelvic arterial anatomyLarge prospective studiesCommon risk factorsQuality of lifeDiagnostic imaging modalitiesMacrovascular diseasePercutaneous revascularizationEndothelial dysfunctionDiabetes mellitusPathophysiological linkProspective studyArterial anatomyClinical eventsCurrent therapiesRisk factors