Featured Publications
Risk profiles, access to care, and outcomes in Hispanics hospitalized for lower extremity peripheral artery disease
Luna P, Harris K, Castro-Dominguez Y, Algara M, Severiche-Mena C, Smolderen KG, Mena-Hurtado C. Risk profiles, access to care, and outcomes in Hispanics hospitalized for lower extremity peripheral artery disease. Journal Of Vascular Surgery 2022, 77: 216-224.e15. PMID: 36037965, DOI: 10.1016/j.jvs.2022.08.021.Peer-Reviewed Original ResearchConceptsPeripheral artery diseaseLower extremity peripheral artery diseaseNon-Hispanic whitesEmergency departmentPAD careArtery diseaseRisk factorsSevere peripheral artery diseaseChronic limb-threatening ischemiaRisk profileNational Inpatient Sample dataCardiovascular risk factorsLimb-threatening ischemiaPatients' sociodemographic characteristicsWorse clinical outcomesMultivariable logistic regressionAssociation of ethnicityLength of stayHealth care consumptionHealth care coveragePAD hospitalizationsPrior amputationEndovascular revascularizationED admissionRenal failureSecondary interventions following open vs endovascular revascularization for chronic limb threatening ischemia in the BEST-CLI trial
Conte M, Azene E, Doros G, Gasper W, Hamza T, Kashyap V, Guzman R, Mena-Hurtado C, Menard M, Rosenfield K, Rowe V, Strong M, Farber A. Secondary interventions following open vs endovascular revascularization for chronic limb threatening ischemia in the BEST-CLI trial. Journal Of Vascular Surgery 2024, 79: 1428-1437.e4. PMID: 38368997, DOI: 10.1016/j.jvs.2024.02.005.Peer-Reviewed Original ResearchIntention-to-treatBEST-CLIChronic limb-threatening ischemiaOpen bypassRe-interventionBEST-CLI trialCohort 1Limb-threatening ischemiaSecondary analysisCox regression modelsOpen armMultivariate Cox regression modelRegression modelsDuration of follow-upTrial cohortCohortAnalyzed dataRandomized trialsFollow-upReduced hazardEndovascular revascularizationCLTIInitial treatmentTrialsStudy endpoint
2023
Secondary Interventions Following Open vs Endovascular Revascularization for Chronic Limb-threatening Ischemia in the BEST-CLI Trial
Conte M, Azene E, Gasper W, Guzman R, Hamza T, Kashyap V, Mena-Hurtado C, Menard M, Rosenfield K, Rowe V, Farber A. Secondary Interventions Following Open vs Endovascular Revascularization for Chronic Limb-threatening Ischemia in the BEST-CLI Trial. Journal Of Vascular Surgery 2023, 77: e80-e81. DOI: 10.1016/j.jvs.2023.03.091.Peer-Reviewed Original ResearchChronic limb-threatening ischemiaBEST-CLI trialLimb-threatening ischemiaBEST-CLIEndovascular revascularizationIntervention to optimize follow-up after lower extremity revascularization
Kim T, Lee S, Gorecka J, Baratta V, Elliston S, Fillion S, Mena-Hurtado C, Mojibian H, Ahuja V, Guzman R, Chaar C. Intervention to optimize follow-up after lower extremity revascularization. JVS-Vascular Insights 2023, 1: 100005. DOI: 10.1016/j.jvsvi.2023.100005.Peer-Reviewed Original ResearchLower extremity revascularizationVascular specialistsExtremity revascularizationQI interventionsAcute limb ischemiaHistory of diabetesPeripheral arterial diseaseTertiary care centerMajority of patientsQuality improvement interventionsBrief telephone surveyRest painEndovascular revascularizationChart reviewLimb ischemiaArterial diseaseIndex procedureMean ageWorse outcomesCare centerObjective PatientsVascular carePatientsTissue lossImprovement interventions
2022
Association of depression and anxiety disorders with outcomes after revascularization in chronic limb-threatening ischemia hospitalizations nationwide
Harris KM, Mena-Hurtado C, Burg MM, Vriens PW, Heyligers J, Smolderen KG. Association of depression and anxiety disorders with outcomes after revascularization in chronic limb-threatening ischemia hospitalizations nationwide. Journal Of Vascular Surgery 2022, 77: 480-489. PMID: 36115521, DOI: 10.1016/j.jvs.2022.09.008.Peer-Reviewed Original ResearchConceptsLength of stayChronic limb-threatening ischemiaAnxiety disorder diagnosisAssociation of depressionRevascularization cohortMajor amputationDisorder diagnosisSurgical revascularizationEndovascular revascularizationHigher oddsLonger median LOSMedian LOSLonger LOSAnxiety disordersDocumentation of depressionPeripheral artery diseaseLimb-threatening ischemiaRisk of amputationNational Inpatient SamplePatients' sociodemographic dataHigher median costArtery diseaseIllness severityPsychiatric comorbidityComorbid depressionImpact of malnutrition and frailty on mortality and major amputation in patients with CLTI
Karim AM, Li J, Panhwar MS, Arshad S, Shalabi S, Mena‐Hurtado C, Aronow HD, Secemsky EA, Shishehbor MH. Impact of malnutrition and frailty on mortality and major amputation in patients with CLTI. Catheterization And Cardiovascular Interventions 2022, 99: 1300-1309. PMID: 35114067, DOI: 10.1002/ccd.30113.Peer-Reviewed Original ResearchConceptsFrail patientsMajor amputationFrailty Risk ScoreClinical Modification codesImpact of malnutritionManagement of frailtyNational Inpatient SamplePrevalence of malnutritionMultivariable regression analysisOutcomes of interestCLTI patientsHospital mortalityEndovascular revascularizationMortality benefitAdverse eventsFrailty statusRevascularization methodInpatient SampleHospital costsInvasive approachRisk scoreInternational ClassificationCLTIPatientsNutritional status
2020
Efficacy and safety of intravascular lithotripsy for the treatment of peripheral arterial disease: An individual patient‐level pooled data analysis
Madhavan MV, Shahim B, Mena‐Hurtado C, Garcia L, Crowley A, Parikh SA. Efficacy and safety of intravascular lithotripsy for the treatment of peripheral arterial disease: An individual patient‐level pooled data analysis. Catheterization And Cardiovascular Interventions 2020, 95: 959-968. PMID: 31957955, PMCID: PMC7187419, DOI: 10.1002/ccd.28729.Peer-Reviewed Original ResearchConceptsIndividual patient-level dataPeripheral arterial diseaseUse of IVLIntravascular lithotripsyArterial diseaseProspective studyTreatment of PADSafety of IVLPeripheral arterial calcificationPeripheral artery calcificationPeripheral intravascular lithotripsyProcedural angiographic complicationsFlow-limiting dissectionIndependent core laboratoryTreatment of patientsPercent diameter stenosisLong-term patencyPatient-level dataAngiographic complicationsAcute successEfficacy endpointEndovascular revascularizationSafety endpointArtery calcificationDistal embolization
2015
Local delivery of paclitaxel in the treatment of peripheral arterial disease
Ng VG, Mena C, Pietras C, Lansky AJ. Local delivery of paclitaxel in the treatment of peripheral arterial disease. European Journal Of Clinical Investigation 2015, 45: 333-345. PMID: 25615282, DOI: 10.1111/eci.12407.Peer-Reviewed Original ResearchConceptsPeripheral artery diseaseEndovascular revascularizationArtery diseaseLocal deliveryClinical studiesLocal drug deliveryPeripheral arterial diseasePeripheral vascular diseasePrimary patency rateSystemic adverse effectsUse of paclitaxelLong-term efficacyDrug-Eluting BalloonDrug-eluting stentsTerms of efficacyBrief exposure periodArterial diseaseBalloon angioplastyPatency ratesVascular diseaseBalloon catheterCoated balloonMEDLINE searchStent failureActive drugEndovascular Treatment of Below the Knee Arteries
Ward C, Gamberdella J, Mena-Hurtado C. Endovascular Treatment of Below the Knee Arteries. 2015, 3195-3203. DOI: 10.1007/978-3-642-37078-6_192.Peer-Reviewed Original ResearchPatient-specific challengesBTK interventionKnee revascularizationPeriprocedural medicationsArterial revascularizationEndovascular revascularizationKnee arteriesEndovascular treatmentBTK arteriesAngiosome conceptWidespread therapyEndovascular specialistsAnatomical considerationsRevascularizationPatientsArteryAccess approachMedicationsTherapy
2014
Endovascular Treatment of Below-the-Knee Arteries
Ward C, Gamberdella J, Mena-Hurtado C. Endovascular Treatment of Below-the-Knee Arteries. 2014, 1-11. DOI: 10.1007/978-3-642-37393-0_192-2.Peer-Reviewed Original ResearchPatient-specific challengesBTK interventionKnee revascularizationPeriprocedural medicationsArterial revascularizationEndovascular revascularizationKnee arteriesEndovascular treatmentBTK arteriesAngiosome conceptWidespread therapyEndovascular specialistsAnatomical considerationsRevascularizationPatientsArteryAccess approachMedicationsTherapy