2024
Patterns of sub‐optimal change following CBT for childhood anxiety
Bertie L, Arendt K, Coleman J, Cooper P, Creswell C, Eley T, Hartman C, Heiervang E, In‐Albon T, Krause K, Lester K, Marin C, Nauta M, Rapee R, Schneider S, Schniering C, Silverman W, Thastum M, Thirlwall K, Waite P, Wergeland G, Hudson J. Patterns of sub‐optimal change following CBT for childhood anxiety. Journal Of Child Psychology And Psychiatry 2024, 65: 1612-1623. PMID: 38817012, PMCID: PMC11563922, DOI: 10.1111/jcpp.14009.Peer-Reviewed Original ResearchCognitive behavioral therapyAnxiety disordersAnxiety diagnosesGrowth curve modelsMinimal respondersGroup cognitive behavioral therapyPatterns of symptom changeCurve modelClinically anxious youthSocial anxiety disorderAssociated with significantly less improvementResponse patternsAssess patterns of changeAnxious youthDisorder remissionChildhood anxietyMaternal psychopathologyBehavioral therapyDisorder severityDiagnostic statusSymptom changePre-and post-treatmentDelayed respondersAnxietyParental factorsChanges in Frontoamygdala Circuitry Associated With a Parent-Focused Intervention for Pediatric Anxiety Disorders
Gee D, Gunther K, Petrie D, Kitt E, Keding T, Broussard A, Zacharek S, Nardini C, Hommel G, Martino A, Anderson T, Spencer H, Odriozola P, Marin C, Silverman W, Lebowitz E. Changes in Frontoamygdala Circuitry Associated With a Parent-Focused Intervention for Pediatric Anxiety Disorders. Biological Psychiatry 2024, 95: s44. DOI: 10.1016/j.biopsych.2024.02.110.Peer-Reviewed Original ResearchFamily Accommodation in Anxious Irritable and Anxious Nonirritable Youth
Budagzad-Jacobson R, Musicaro R, Marin C, Silverman W, Lebowitz E. Family Accommodation in Anxious Irritable and Anxious Nonirritable Youth. Behavior Therapy 2024, 55: 913-921. PMID: 39174269, PMCID: PMC11341947, DOI: 10.1016/j.beth.2024.03.003.Peer-Reviewed Original ResearchFamily accommodationIrritable youthYouth anxietyParent ratingsCo-occurrence of anxietyLevels of irritabilityInfluence of irritabilityClinic-referredAnxiety disordersDiagnostic InterviewChild anxietyYouth ratingsAnxietyAccommodation behaviorAnxiety levelsTreatment targetModerating effectIrritability levelsYouthCo-occurrenceParentsIrritationDisordersFindingsAssociationResponding to threat: Associations between neural reactivity to and behavioral avoidance of threat in pediatric anxiety
Kitt E, Zacharek S, Odriozola P, Nardini C, Hommel G, Martino A, Anderson T, Spencer H, Broussard A, Dean J, Marin C, Silverman W, Lebowitz E, Gee D. Responding to threat: Associations between neural reactivity to and behavioral avoidance of threat in pediatric anxiety. Journal Of Affective Disorders 2024, 351: 818-826. PMID: 38290579, PMCID: PMC10981528, DOI: 10.1016/j.jad.2024.01.204.Peer-Reviewed Original ResearchConceptsReactivity to threatMeasures of avoidanceVentral anterior insulaClinician-based measuresNeural reactivityPediatric anxietyAnxiety disordersBehavioral avoidanceFunctional magnetic resonance imaging taskAmygdala functional connectivityVentromedial prefrontal cortexTreatment-seeking sampleAvoidance of threatClinically significant constructsAssociated with tasksGeneralizability of findingsPrefrontal cortexAnterior insulaNeural findingsLaboratory tasksFunctional connectivityAnxietyAmygdalaAvoidanceSignificant constructs
2023
Boundaries on Parent Involvement in Their Child’s Anxiety Cognitive-Behavioral-Treatment Outcome: Parent Reinforcement and Relationship Behaviors Moderate Outcome
Silverman W, Rey Y, Marin C, Boutris P, Jaccard J, Pettit J. Boundaries on Parent Involvement in Their Child’s Anxiety Cognitive-Behavioral-Treatment Outcome: Parent Reinforcement and Relationship Behaviors Moderate Outcome. Clinical Psychological Science 2023, 12: 936-944. PMID: 39474312, PMCID: PMC11521139, DOI: 10.1177/21677026231209331.Peer-Reviewed Original ResearchCognitive-behavioral treatmentParent reinforcementParents’ psychological controlPsychological controlCognitive behavioralRelationship behaviorsLower anxietyAnxiety disordersModeration effectPositive reinforcementParent involvementYouthAnxietyResearch replicationParentsModerate outcomeTrainingTreatment outcomesModeratorEfficacy trialsReinforcementChildrenOutcomesDisordersImplicationsAffective Language Spreads Between Anxious Children and Their Mothers During a Challenging Puzzle Task
Nook E, Nardini C, Zacharek S, Hommel G, Spencer H, Martino A, Morra A, Flores S, Anderson T, Marin C, Silverman W, Lebowitz E, Gee D. Affective Language Spreads Between Anxious Children and Their Mothers During a Challenging Puzzle Task. Emotion 2023, 23: 1513-1521. PMID: 36595385, PMCID: PMC10314965, DOI: 10.1037/emo0001203.Peer-Reviewed Original ResearchConceptsNegative affect wordsChallenging puzzle taskAffect wordsAffective languagePuzzle taskEffective emotion regulationSpread of emotionsEmotion regulationNeuroscientific levelAnxious childrenEmotional influencesWord useBidirectional influenceAnxiety disordersBidirectional relationsMother's directionsMental healthEmotionsFuture researchWordsCurrent studyLanguageChildrenTaskMothersThe Role of Family-Level Factors in Childhood Anxiety During the COVID-19 Pandemic
Kitt E, Cohodes E, McCauley S, Hommel G, Nardini C, Zacharek S, Martino A, Anderson T, Spencer H, Odriozola P, Spurrier G, Broussard A, Marin C, Silverman W, Lebowitz E, Gee D. The Role of Family-Level Factors in Childhood Anxiety During the COVID-19 Pandemic. Journal Of Emotion And Psychopathology 2023, 1: 129-151. DOI: 10.55913/joep.v1i1.18.Peer-Reviewed Original ResearchCOVID-19-related fearCOVID-19-related stressFamily-level factorsAmygdala reactivityAnxiety disordersChildren's useEmotion regulation strategiesParent-child dynamicsExpressive suppressionAnxious youthFearful facesChildhood anxietyFMRI taskPediatric anxietyRegulation strategiesOwn functioningCOVID-19 pandemicFamily exposureMultimodal studyFearPervasive disruptionChildren's exposureFamily lifeParental assistanceAnxiety
2022
Parent Involvement Enhances CBTs for Anxiety Disorders in Hispanic/Latino Youth: Acculturation as a Moderator
Patriarca G, Rey Y, Marin C, Yeguez C, Pettit J, Silverman W. Parent Involvement Enhances CBTs for Anxiety Disorders in Hispanic/Latino Youth: Acculturation as a Moderator. Journal Of Consulting And Clinical Psychology 2022, 90: 827-836. PMID: 36355650, PMCID: PMC9727821, DOI: 10.1037/ccp0000770.Peer-Reviewed Original ResearchConceptsCognitive-behavioral treatmentAnxiety outcomesParent acculturationAnxiety disordersPsychological controlNegative reinforcementEfficacy of CBTParents’ psychological controlYouth anxiety severityHispanic/Latino youthEvidence-based interventionsYouth ages 6Anxiety severityBehavioral treatmentParents' useLatino youthLatino familiesParent involvementAge 6YouthAcculturation levelAcculturationEnculturationModeratorDisordersYouth social functioning interacts with treatment arm, diagnosis, and gender to predict anxiety treatment outcome
Etkin RG, Marin CE, Silverman WK, Lebowitz ER. Youth social functioning interacts with treatment arm, diagnosis, and gender to predict anxiety treatment outcome. Behaviour Research And Therapy 2022, 156: 104160. PMID: 35870327, DOI: 10.1016/j.brat.2022.104160.Peer-Reviewed Original ResearchConceptsAnxiety treatment outcomesYouth social functioningSocial skillsPositive social interactionsSocial functioningAnxiety diagnosesAnxiety disordersSocial interactionParent-based treatmentChildren's social skillsSocial anxiety disorderYouths' social skillsAnxiety symptom severityYouth genderTreatment outcomesDiagnostic InterviewSymptom severityClinical functioningFunctioningSkillsYouthPredictorsMultiple regression modelDisordersGender
2019
Latino and Non-Latino Parental Treatment Preferences for Child and Adolescent Anxiety Disorders
Seligman LD, Hovey JD, Ibarra M, Hurtado G, Marin CE, Silverman WK. Latino and Non-Latino Parental Treatment Preferences for Child and Adolescent Anxiety Disorders. Child Psychiatry & Human Development 2019, 51: 617-624. PMID: 31807934, DOI: 10.1007/s10578-019-00945-x.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyLatino parentsChild anxietyNon-Latino white parentsAdolescent anxiety disordersParental involvementParental treatment preferencesPerception of burdenMental health treatmentNon-Latino parentsPotential treatment barriersYouth anxietyBehavioral therapyAnxiety disordersChild's treatmentParent involvementTreatment involvementAnxietyHealth treatmentWhite parentsTreatment barriersParents' preferencesGreater preferenceParentsCurrent studyThe Utility of the SCAS-C/P to Detect Specific Anxiety Disorders Among Clinically Anxious Children
Reardon T, Creswell C, Lester KJ, Arendt K, Blatter-Meunier J, Bögels SM, Coleman JRI, Cooper PJ, Heiervang ER, Herren C, Hogendoorn SM, Hudson JL, Keers R, Lyneham HJ, Marin CE, Nauta M, Rapee RM, Roberts S, Schneider S, Silverman WK, Thastum M, Thirlwall K, Wergeland GJ, Eley TC. The Utility of the SCAS-C/P to Detect Specific Anxiety Disorders Among Clinically Anxious Children. Psychological Assessment 2019, 31: 1006-1018. PMID: 31070449, PMCID: PMC6671872, DOI: 10.1037/pas0000700.Peer-Reviewed Original ResearchConceptsSpence Children's Anxiety ScaleSpecific anxiety disordersSocial phobia subscaleSocial anxiety disorderAnxiety disordersFear subscaleQuestionnaire measuresSeparation anxietyGeneralized anxietyAnxiety ScalePreadolescent childrenChildren's Anxiety ScaleClinic-referred sampleSeparation anxiety disorderSeparation anxiety subscaleContribution of childrenFull diagnostic assessmentSCAS subscalesAnxious childrenSocial phobiaChild reportsOptimal cutoff scoreAnxiety subscaleAnxietyCorresponding disorderGroup- Versus Parent-Involvement CBT for Childhood Anxiety Disorders: Treatment Specificity and Long-Term Recovery Mediation
Silverman WK, Marin CE, Rey Y, Kurtines WM, Jaccard J, Pettit JW. Group- Versus Parent-Involvement CBT for Childhood Anxiety Disorders: Treatment Specificity and Long-Term Recovery Mediation. Clinical Psychological Science 2019, 7: 840-855. PMID: 33758679, PMCID: PMC7984418, DOI: 10.1177/2167702619830404.Peer-Reviewed Original ResearchGroup cognitive behavioral therapyParental psychological controlPsychological controlAnxiety reductionAnxiety disordersYouth anxiety disordersChildhood anxiety disordersPrimary anxiety diagnosisCognitive behavioral therapyTreatment specificityYouth anxietyCBT targetsBehavioral therapyAnxiety diagnosesCBTMediationPutative mediatorsPosttreatmentDisordersAnxietyYouthEfficacy trialsMediatorsParentsSpecific mechanismsParent-Based Treatment as Efficacious as Cognitive-Behavioral Therapy for Childhood Anxiety: A Randomized Noninferiority Study of Supportive Parenting for Anxious Childhood Emotions
Lebowitz ER, Marin C, Martino A, Shimshoni Y, Silverman WK. Parent-Based Treatment as Efficacious as Cognitive-Behavioral Therapy for Childhood Anxiety: A Randomized Noninferiority Study of Supportive Parenting for Anxious Childhood Emotions. Journal Of The American Academy Of Child & Adolescent Psychiatry 2019, 59: 362-372. PMID: 30851397, PMCID: PMC6732048, DOI: 10.1016/j.jaac.2019.02.014.Peer-Reviewed Original ResearchConceptsParent-based treatmentAnxious Childhood EmotionsChildhood anxiety disordersFamily accommodationChildhood anxietyAnxiety disordersChildhood EmotionsSupportive parentingParenting stressAnxiety outcomesCognitive behavioral therapyPrimary anxiety disorderParent interventionBehavioral therapyChildren's ratingsAnxiety severityTreatment credibilityClinician-rated scalesParent treatmentParent involvementAnxietyDiagnostic InterviewEmotionsParentingIndependent evaluators
2017
Parental Acculturation Level Moderates Outcome in Peer-Involved and Parent-Involved CBT for Anxiety Disorders in Latino Youth
Vaclavik D, Buitron V, Rey Y, Marin CE, Silverman WK, Pettit JW. Parental Acculturation Level Moderates Outcome in Peer-Involved and Parent-Involved CBT for Anxiety Disorders in Latino Youth. Journal Of Latinx Psychology 2017, 5: 261-274. PMID: 29226037, PMCID: PMC5720156, DOI: 10.1037/lat0000095.Peer-Reviewed Original ResearchCognitive behavioral therapyGroup CBTParental acculturationLatino youthAnxiety disordersAnxiety outcomesEfficacy of CBTGroup cognitive behavioral therapyAnxiety scoresCBT outcomeBehavioral therapyUS cultureParental acculturation levelYouthAcculturation levelAcculturationModeratorEfficacious treatmentModerate outcomeDisordersHigh levelsFurther evidencePeersScoresLow levels
2016
Genome-wide association study of response to cognitive–behavioural therapy in children with anxiety disorders
Coleman JR, Lester KJ, Keers R, Roberts S, Curtis C, Arendt K, Bögels S, Cooper P, Creswell C, Dalgleish T, Hartman CA, Heiervang ER, Hötzel K, Hudson JL, In-Albon T, Lavallee K, Lyneham HJ, Marin CE, Meiser-Stedman R, Morris T, Nauta MH, Rapee RM, Schneider S, Schneider SC, Silverman WK, Thastum M, Thirlwall K, Waite P, Wergeland GJ, Breen G, Eley TC. Genome-wide association study of response to cognitive–behavioural therapy in children with anxiety disorders. The British Journal Of Psychiatry 2016, 209: 236-243. PMID: 26989097, PMCID: PMC5007453, DOI: 10.1192/bjp.bp.115.168229.Peer-Reviewed Original Research
2015
Predictors of treatment outcome in an effectiveness trial of cognitive behavioral therapy for children with anxiety disorders
Wergeland GJ, Fjermestad KW, Marin CE, Bjelland I, Haugland BS, Silverman WK, Öst LG, Bjaastad JF, Oeding K, Havik OE, Heiervang ER. Predictors of treatment outcome in an effectiveness trial of cognitive behavioral therapy for children with anxiety disorders. Behaviour Research And Therapy 2015, 76: 1-12. PMID: 26583954, DOI: 10.1016/j.brat.2015.11.001.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyChild-rated anxiety symptomsParent internalizing symptomsAnxiety disordersAnxiety symptomsCBT programInternalizing symptomsSocial phobiaBehavioral therapyLower family social classPrimary anxiety disorderSeparation anxiety disorderPositive treatment outcomesFamily social classChildren of parentsAnxious childrenEffectiveness trialChildren's motivationParent factorsSeparation anxietyTreatment outcomesSymptom levelsRecent effectiveness studiesPoor outcomePhobiaClinical Predictors of Response to Cognitive-Behavioral Therapy in Pediatric Anxiety Disorders: The Genes for Treatment (GxT) Study
Hudson JL, Keers R, Roberts S, Coleman JR, Breen G, Arendt K, Bögels S, Cooper P, Creswell C, Hartman C, Heiervang ER, Hötzel K, In-Albon T, Lavallee K, Lyneham HJ, Marin CE, McKinnon A, Meiser-Stedman R, Morris T, Nauta M, Rapee RM, Schneider S, Schneider SC, Silverman WK, Thastum M, Thirlwall K, Waite P, Wergeland GJ, Lester KJ, Eley TC. Clinical Predictors of Response to Cognitive-Behavioral Therapy in Pediatric Anxiety Disorders: The Genes for Treatment (GxT) Study. Journal Of The American Academy Of Child & Adolescent Psychiatry 2015, 54: 454-463. PMID: 26004660, PMCID: PMC4469376, DOI: 10.1016/j.jaac.2015.03.018.Peer-Reviewed Original ResearchPredictors of dropout from community clinic child CBT for anxiety disorders
Wergeland GJ, Fjermestad KW, Marin CE, Haugland BS, Silverman WK, Öst LG, Havik OE, Heiervang ER. Predictors of dropout from community clinic child CBT for anxiety disorders. Journal Of Anxiety Disorders 2015, 31: 1-10. PMID: 25637909, DOI: 10.1016/j.janxdis.2015.01.004.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAmbulatory CareAnxiety DisordersAttitude to HealthChildCognitive Behavioral TherapyCommunity Mental Health CentersFemaleHumansInternal-External ControlMaleMotivationParentsPatient DropoutsPsychiatric Status Rating ScalesPsychotherapy, GroupSelf ConceptSurveys and QuestionnairesConceptsCognitive behavior therapyTreatment credibilityOverall dropoutsAnxiety disordersLate dropoutGroup cognitive behavior therapyInternalizing symptomsPredictors of dropoutCommunity clinicsEffectiveness trialTreatment dropoutLower childSymptomsBehavior therapyEarly dropoutSignificant differencesChildrenPredictorsDisordersDropout rateClinicTherapyParentsDropoutTrialsFamily accommodation mediates the association between anxiety symptoms in mothers and children
Jones JD, Lebowitz ER, Marin CE, Stark KD. Family accommodation mediates the association between anxiety symptoms in mothers and children. Journal Of Child And Adolescent Mental Health 2015, 27: 41-51. PMID: 25958796, DOI: 10.2989/17280583.2015.1007866.Peer-Reviewed Original ResearchConceptsFamily accommodationChild anxietyStructural equation modellingAnxiety symptomsMaternal anxietySubclinical anxiety symptomsPediatric anxiety disordersDevelopment of interventionsChild avoidMothers of childrenMediational roleGreater symptom severityAnxiety disordersOwn anxietyMaternal accommodationAnxietyEquation modellingPoor treatment outcomesSymptom severityParentsChildrenTreatment outcomesAccommodationYouthMothers
2014
An effectiveness study of individual vs. group cognitive behavioral therapy for anxiety disorders in youth
Wergeland GJ, Fjermestad KW, Marin CE, Haugland BS, Bjaastad JF, Oeding K, Bjelland I, Silverman WK, Öst L, Havik OE, Heiervang ER. An effectiveness study of individual vs. group cognitive behavioral therapy for anxiety disorders in youth. Behaviour Research And Therapy 2014, 57: 1-12. PMID: 24727078, DOI: 10.1016/j.brat.2014.03.007.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyWaitlist controlAnxiety disordersBehavioral therapyEffectiveness of CBTGroup cognitive behavioral therapyPrincipal anxiety disorderGroup treatment approachClinical severity ratingsCBT programSocial phobiaSeparation anxietyStatistical equivalence testsGCBTSymptom measuresICBTDiagnostic InterviewYouthMore youthAnxietyTraditional hypothesis testsEquivalence testCommunity settingsRelative effectivenessDisorders