2022
Opioid tapering support using a web-based app: Development and protocol for a pilot randomized controlled trial
Edmond SN, Wesolowicz DM, Moore BA, Ibarra J, Chhabra M, Fraenkel L, Becker WC. Opioid tapering support using a web-based app: Development and protocol for a pilot randomized controlled trial. Contemporary Clinical Trials 2022, 119: 106857. PMID: 35863697, DOI: 10.1016/j.cct.2022.106857.Peer-Reviewed Original ResearchConceptsPilot trialLong-term opioid therapyPatient-reported outcomesRandomized-controlled trialQuality of lifeSelf-management skillsOpioid taperOpioid therapyOpioid usePrimary outcomePrimary careTwo-armLimited efficacyInteractive web-based programControl groupIntervention MappingWeb-based programPatientsPeer specialistsTrialsPotential harmSummit programWeb-based appCareOutcomes
2018
Efficacy of Extended-Release Naltrexone on HIV-Related and Drinking Outcomes Among HIV-Positive Patients: A Randomized-Controlled Trial
Edelman EJ, Moore BA, Holt SR, Hansen N, Kyriakides TC, Virata M, Brown ST, Justice AC, Bryant KJ, Fiellin DA, Fiellin LE. Efficacy of Extended-Release Naltrexone on HIV-Related and Drinking Outcomes Among HIV-Positive Patients: A Randomized-Controlled Trial. AIDS And Behavior 2018, 23: 211-221. PMID: 30073637, PMCID: PMC6476298, DOI: 10.1007/s10461-018-2241-z.Peer-Reviewed Original ResearchConceptsHIV-positive patientsHeavy drinking daysVACS Index scoreXR-NTXART adherenceDrinking daysIndex scoreUndetectable HIV viral loadCD4 cell countExtended-release naltrexoneDouble-blind placeboHIV viral loadRandomized-controlled trialDrinking outcomesHIV biomarkersSecondary outcomesHIV outcomesPrimary outcomeViral loadAntiretroviral adherenceClinical trialsCell countAlcohol treatmentHIVPatients