2013
HIV Testing and Sexual Risk Reduction Counseling in Office-Based Buprenorphine/Naloxone Treatment
Edelman EJ, Moore BA, Caffrey S, Sikkema KJ, Jones ES, Schottenfeld RS, Fiellin DA, Fiellin LE. HIV Testing and Sexual Risk Reduction Counseling in Office-Based Buprenorphine/Naloxone Treatment. Journal Of Addiction Medicine 2013, 7: 410-416. PMID: 24189173, DOI: 10.1097/adm.0b013e3182a3b603.Peer-Reviewed Original ResearchConceptsSexual risk reduction counselingRisk reduction counselingBuprenorphine/naloxone treatmentOpioid-dependent patientsReduction counselingSexual risk behaviorsHIV testingNaloxone treatmentHuman immunodeficiency virus (HIV) testingRisk behaviorsPreliminary efficacyVirus testingPatientsManual adherenceTreatment practicesProcess measuresCounseling sessionsSimilar proportionsHIVCounselingOutcomesTreatmentSessionsRandomizedTestingA Randomized Trial of Cognitive Behavioral Therapy in Primary Care-based Buprenorphine
Fiellin DA, Barry DT, Sullivan LE, Cutter CJ, Moore BA, O'Connor PG, Schottenfeld RS. A Randomized Trial of Cognitive Behavioral Therapy in Primary Care-based Buprenorphine. The American Journal Of Medicine 2013, 126: 74.e11-74.e17. PMID: 23260506, PMCID: PMC3621718, DOI: 10.1016/j.amjmed.2012.07.005.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyPhysician managementBehavioral therapyOpioid useOpioid dependencePrimary careSelf-reported frequencyBuprenorphine/naloxone treatmentConsecutive weeksOpioid-dependent patientsIllicit opioid usePrimary care clinicsPrimary outcome measureWeeks of treatmentNaloxone treatmentOpioid abstinenceBuprenorphine/Care clinicsIllicit opioidsRandomized trialsUrine toxicologyClinical trialsStudy completionOutcome measuresCocaine use
2012
Brief versus extended counseling along with buprenorphine/naloxone for HIV-infected opioid dependent patients
Tetrault JM, Moore BA, Barry DT, O'Connor PG, Schottenfeld R, Fiellin DA, Fiellin LE. Brief versus extended counseling along with buprenorphine/naloxone for HIV-infected opioid dependent patients. Journal Of Substance Use And Addiction Treatment 2012, 43: 433-439. PMID: 22938914, DOI: 10.1016/j.jsat.2012.07.011.Peer-Reviewed Original ResearchMeSH KeywordsAdultBuprenorphineBuprenorphine, Naloxone Drug CombinationCounselingDelivery of Health Care, IntegratedFeasibility StudiesFemaleFollow-Up StudiesHIV InfectionsHumansMaleMiddle AgedNaloxoneNarcotic AntagonistsOpioid-Related DisordersPsychotherapy, BriefSubstance Abuse DetectionTime FactorsTreatment OutcomeViral LoadConceptsEnhanced medical managementPhysician managementDetectable HIV viral loadHIV treatment settingsOpioid-negative urinesBuprenorphine/naloxoneHIV viral loadOpioid-dependent patientsPercentage of subjectsUntreated opioid dependenceExtended counselingHIV clinicHIV outcomesBuprenorphine/Medical managementOpioid dependenceViral loadDependent patientsExtensive counselingClinical trialsContinuous abstinenceNegative urineTreatment settingsGroup differencesCounselingCost-Effectiveness of Long-Term Outpatient Buprenorphine-Naloxone Treatment for Opioid Dependence in Primary Care
Schackman BR, Leff JA, Polsky D, Moore BA, Fiellin DA. Cost-Effectiveness of Long-Term Outpatient Buprenorphine-Naloxone Treatment for Opioid Dependence in Primary Care. Journal Of General Internal Medicine 2012, 27: 669-676. PMID: 22215271, PMCID: PMC3358393, DOI: 10.1007/s11606-011-1962-8.Peer-Reviewed Original ResearchMeSH KeywordsBuprenorphineCost of IllnessCost-Benefit AnalysisDecision Support TechniquesDrug Administration ScheduleDrug CombinationsDrug CostsHealth Care CostsHumansLong-Term CareMedication AdherenceNaloxoneNarcotic AntagonistsOpiate Substitution TreatmentOpioid-Related DisordersPrimary Health CareQuality-Adjusted Life YearsSensitivity and SpecificityUnited StatesConceptsQuality-adjusted life yearsBUP/NXProbabilistic sensitivity analysesBup/Stable patientsOpioid dependenceLife weightsStable opioid-dependent patientsIncremental cost-effectiveness ratioOpioid-dependent patientsOpioid-dependent individualsOffice-based settingSocietal cost savingsCost-effectiveness ratioDecision analytic modelBroader health systemBuprenorphine-naloxoneOpioid useCohort studyNaloxone treatmentCare physiciansAdditional researchPrimary carePatient costsHypothetical cohort
2007
Primary Care Office-based Buprenorphine Treatment: Comparison of Heroin and Prescription Opioid Dependent Patients
Moore BA, Fiellin DA, Barry DT, Sullivan LE, Chawarski MC, O’Connor P, Schottenfeld RS. Primary Care Office-based Buprenorphine Treatment: Comparison of Heroin and Prescription Opioid Dependent Patients. Journal Of General Internal Medicine 2007, 22: 527-530. PMID: 17372805, PMCID: PMC1829433, DOI: 10.1007/s11606-007-0129-0.Peer-Reviewed Original ResearchConceptsPrescription opioid useOpioid useOnly patientsPrescription opioidsTreatment outcomesBuprenorphine/naloxone maintenanceBuprenorphine/naloxone treatmentOpioid-negative urine samplesPrescription opioid-dependent patientsHepatitis C antibodyDrug treatment historyOpioid-dependent patientsPrimary care officesOffice-based settingClinical characteristicsBuprenorphine treatmentNaloxone treatmentBuprenorphine/Opioid dependenceCare officesDependent patientsTreatment responseC antibodyHeroin usePatients
2006
A Trial of Integrated Buprenorphine/Naloxone and HIV Clinical Care
Sullivan LE, Barry D, Moore BA, Chawarski MC, Tetrault JM, Pantalon MV, O'Connor PG, Schottenfeld RS, Fiellin DA. A Trial of Integrated Buprenorphine/Naloxone and HIV Clinical Care. Clinical Infectious Diseases 2006, 43: s184-s190. PMID: 17109305, DOI: 10.1086/508182.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, SublingualAdultAntiretroviral Therapy, Highly ActiveBuprenorphineDose-Response Relationship, DrugDrug Administration ScheduleFemaleFollow-Up StudiesHIV InfectionsHumansMaleMiddle AgedNaloxoneNarcotic AntagonistsOpioid-Related DisordersPilot ProjectsProbabilityReference ValuesRisk FactorsTreatment OutcomeConceptsHIV clinical careHIV-1 RNA copies/mLBuprenorphine/naloxone treatmentRNA copies/mLCopies/mLOpioid dependenceClinical careOpioid useNaloxone treatmentPhysician managementTreatment retentionHIV type 1 RNA levelsHIV-1 RNA levelsDose of buprenorphinePartial opioid agonistRNA levelsCD4 lymphocyte countBuprenorphine/naloxoneOpioid-dependent patientsUrine toxicology testsWeeks of treatmentHuman immunodeficiency virusUrine test resultsBetter treatment retentionUntreated opioid dependence
1998
AIDS Risk Behavior in Opioid Dependent Patients Treated with Community Reinforcement Approach and Relationships with Psychiatric Disorders
Abbott P, Moore B, Weller S, Delaney H. AIDS Risk Behavior in Opioid Dependent Patients Treated with Community Reinforcement Approach and Relationships with Psychiatric Disorders. Journal Of Addictive Diseases 1998, 17: 33-48. PMID: 9848030, DOI: 10.1300/j069v17n04_04.Peer-Reviewed Original ResearchConceptsOpioid-dependent patientsComorbid psychiatric disordersAIDS risk behaviorsCommunity Reinforcement ApproachSocial Adjustment Scale-Self ReportRisk behaviorsPsychiatric disordersDependent patientsLarge clinical trialsMethadone maintenance treatmentBeck Depression InventoryOpioid dependenceMaintenance treatmentStandard treatmentClinical trialsASI composite scoresReinforcement approachMultivariate analysisDepression InventorySubstance abuse variablesSeverity IndexComposite scoreDisordersPatientsPrimary predictor