2022
The Species-Specific 282 Residue in the PB2 Subunit of the Polymerase Regulates RNA Synthesis and Replication of Influenza A Viruses Infecting Bat and Nonbat Hosts
Banerjee S, De A, Kedia N, Bhakta K, Wang L, Bhattacharjee B, Mondal A. The Species-Specific 282 Residue in the PB2 Subunit of the Polymerase Regulates RNA Synthesis and Replication of Influenza A Viruses Infecting Bat and Nonbat Hosts. Journal Of Virology 2022, 96: e02190-21. PMID: 35044213, PMCID: PMC8906409, DOI: 10.1128/jvi.02190-21.Peer-Reviewed Original ResearchConceptsBat influenza virusesInfluenza virus polymeraseInfluenza A virusVirus polymerasePB2 subunitIAV RNA polymeraseGenera of influenza virusesHost speciesAdaptation of influenza virusesInfluenza virusHuman cellsPolymerase subunit PB2RNA synthesis activitySpecies-specific signaturesHuman-specific signaturesAmino acid preferencesReduced polymerase activityAmino acid alterationsGlutamic acidA virusSurface antigen hemagglutininCross-species transmissionRNA polymerasePB2 proteinSignature residues
2014
RNA and β-Hemolysin of Group B Streptococcus Induce Interleukin-1β (IL-1β) by Activating NLRP3 Inflammasomes in Mouse Macrophages*
Gupta R, Ghosh S, Monks B, DeOliveira R, Tzeng T, Kalantari P, Nandy A, Bhattacharjee B, Chan J, Ferreira F, Rathinam V, Sharma S, Lien E, Silverman N, Fitzgerald K, Firon A, Trieu-Cuot P, Henneke P, Golenbock D. RNA and β-Hemolysin of Group B Streptococcus Induce Interleukin-1β (IL-1β) by Activating NLRP3 Inflammasomes in Mouse Macrophages*. Journal Of Biological Chemistry 2014, 289: 13701-13705. PMID: 24692555, PMCID: PMC4022842, DOI: 10.1074/jbc.c114.548982.Peer-Reviewed Original Research