RNA and β-Hemolysin of Group B Streptococcus Induce Interleukin-1β (IL-1β) by Activating NLRP3 Inflammasomes in Mouse Macrophages*
Gupta R, Ghosh S, Monks B, DeOliveira R, Tzeng T, Kalantari P, Nandy A, Bhattacharjee B, Chan J, Ferreira F, Rathinam V, Sharma S, Lien E, Silverman N, Fitzgerald K, Firon A, Trieu-Cuot P, Henneke P, Golenbock D. RNA and β-Hemolysin of Group B Streptococcus Induce Interleukin-1β (IL-1β) by Activating NLRP3 Inflammasomes in Mouse Macrophages*. Journal Of Biological Chemistry 2014, 289: 13701-13705. PMID: 24692555, PMCID: PMC4022842, DOI: 10.1074/jbc.c114.548982.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBacterial ProteinsCarrier ProteinsHemolysin ProteinsHumansInflammasomesInterleukin-1betaLysosomesMacrophagesMiceNLR Family, Pyrin Domain-Containing 3 ProteinPhagosomesRNA, BacterialStreptococcus agalactiae