1997
Ion and Bumetanide Binding by the Na-K-Cl Cotransporter
Isenring P, Forbush B. Ion and Bumetanide Binding by the Na-K-Cl Cotransporter. Journal Of Biological Chemistry 1997, 272: 24556-24562. PMID: 9305921, DOI: 10.1074/jbc.272.39.24556.Peer-Reviewed Original ResearchConceptsNa-K-Cl cotransporterNa-K-ClBumetanide-sensitive 86Rb influxCation-chloride cotransporter familyApparent affinityHEK-293 cellsInhibitor bumetanideCell surface deliveryElectrolyte secretionTime course of activationBumetanidePolarized epitheliaBumetanide bindingCotransporterCl- mediumCotransported ionsHEK-293SNKCC1Hydrophobic central domainSurface deliveryCourse of activationCentral domainTime courseCytoplasmic N-Chimera approach
1992
Na-K-Cl cotransport in the shark rectal gland. I. Regulation in the intact perfused gland
Forbush B, Haas M, Lytle C. Na-K-Cl cotransport in the shark rectal gland. I. Regulation in the intact perfused gland. American Journal Of Physiology 1992, 262: c1000-c1008. PMID: 1566806, DOI: 10.1152/ajpcell.1992.262.4.c1000.Peer-Reviewed Original ResearchConceptsNa-K-ClNa-K-Cl cotransport systemNa-K-Cl cotransporterVasoactive intestinal peptideCotransport systemVIP-stimulated increasesStimulation of secretionShark rectal glandK exitBasolateral membranePerfused glandShark Squalus acanthiasIntestinal peptideArterial-venous differencesDogfish shark Squalus acanthiasIntact glandsPerfusion solutionPerfusion periodBasal statePerfusionGlandInvestigate regulationRectal glandRinger's solutionTime course
1987
Rapid release of 42K and 86Rb from an occluded state of the Na,K-pump in the presence of ATP or ADP.
Forbush B. Rapid release of 42K and 86Rb from an occluded state of the Na,K-pump in the presence of ATP or ADP. Journal Of Biological Chemistry 1987, 262: 11104-11115. PMID: 2440883, DOI: 10.1016/s0021-9258(18)60932-9.Peer-Reviewed Original Research
1984
Na+ movement in a single turnover of the Na pump.
Forbush B. Na+ movement in a single turnover of the Na pump. Proceedings Of The National Academy Of Sciences Of The United States Of America 1984, 81: 5310-5314. PMID: 6089192, PMCID: PMC391693, DOI: 10.1073/pnas.81.17.5310.Peer-Reviewed Original Research