The cancer-testis antigen, sperm protein 17, a new biomarker and immunological target in head and neck squamous cell carcinoma
Schutt CA, Mirandola L, Figueroa JA, Nguyen DD, Cordero J, Bumm K, Judson BL, Chiriva-Internati M. The cancer-testis antigen, sperm protein 17, a new biomarker and immunological target in head and neck squamous cell carcinoma. Oncotarget 2017, 5: 100280-100287. PMID: 29245977, PMCID: PMC5725019, DOI: 10.18632/oncotarget.22213.Peer-Reviewed Original ResearchNeck squamous cell carcinomaAutologous dendritic cellsAutologous tumor cellsSquamous cell carcinomaHNSCC patientsCancer-testis antigensDendritic cellsCell carcinomaNon-small cell lung cancerTumor cellsSp17 expressionIdeal immunotherapeutic targetSpecific cytotoxic lymphocytesCell lung cancerCurrent treatment modalitiesPotential serological biomarkerSperm protein 17Possible future targetsTherapeutic vaccinesImmunotherapeutic targetPoor prognosisAggressive malignancyMultiple myelomaPeripheral bloodTNM stage