2019
Effects of Hypercholesterolemia and Statin Exposure on Survival in a Large National Cohort of Patients With Cirrhosis
Kaplan DE, Serper M, Mehta R, Fox R, John B, Aytaman A, Baytarian M, Hunt K, Albrecht J, Njei B, Taddei TH, Group V. Effects of Hypercholesterolemia and Statin Exposure on Survival in a Large National Cohort of Patients With Cirrhosis. Gastroenterology 2019, 156: 1693-1706.e12. PMID: 30660733, DOI: 10.1053/j.gastro.2019.01.026.Peer-Reviewed Original ResearchMeSH KeywordsAgedCarcinoma, HepatocellularCholesterolFemaleHeart FailureHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHypercholesterolemiaLiver CirrhosisLiver NeoplasmsMaleMiddle AgedMyocardial InfarctionPropensity ScoreProportional Hazards ModelsRandomized Controlled Trials as TopicRetrospective StudiesStrokeSurvival RateUnited StatesConceptsRetrospective cohort studyStatin exposureLarge national cohortHepatic decompensationStatin useCohort studyHazard ratioNational cohortMultivariable Cox proportional hazards modelsCox proportional hazards modelBaseline total cholesterolPrior statin exposureStatin-naïve subjectsEffect of hypercholesterolemiaVeterans Health AdministrationProportional hazards modelHepatocellular carcinoma developmentDecrease of mortalityRisk-set matchingChild-TurcottePugh classStatin therapyDL increaseTotal cholesterolHepatic function
2016
Corticosteroids Versus Pentoxifylline for Severe Alcoholic Hepatitis
Njei B, Do A, McCarty TR, Fortune BE. Corticosteroids Versus Pentoxifylline for Severe Alcoholic Hepatitis. Journal Of Clinical Gastroenterology 2016, 50: 871-881. PMID: 27404293, PMCID: PMC5065367, DOI: 10.1097/mcg.0000000000000585.Peer-Reviewed Original ResearchMeSH KeywordsAdrenal Cortex HormonesFree Radical ScavengersHepatitis, AlcoholicHumansPentoxifyllineRandomized Controlled Trials as TopicConceptsSevere alcoholic hepatitisAlcoholic hepatitisTrial sequential analysisShort-term mortalityHepatorenal syndromeStudies satisfied inclusion criteriaEffect of corticosteroidsSatisfied inclusion criteriaMortality benefitSignificant morbidityCochrane CollaborationEpidemiologic evidenceCochrane LibraryInclusion criteriaCorticosteroidsHepatitisIndependent reviewersTherapeutic strategiesThird investigatorPentoxifyllinePublication statusPlaceboComprehensive searchMortalityInitial reviewers
2015
Comparative efficacy of antiviral therapy in preventing vertical transmission of hepatitis B: a network meta‐analysis
Njei B, Gupta N, Ewelukwa O, Ditah I, Foma M, Lim JK. Comparative efficacy of antiviral therapy in preventing vertical transmission of hepatitis B: a network meta‐analysis. Liver International 2015, 36: 634-641. PMID: 26352650, PMCID: PMC4824664, DOI: 10.1111/liv.12959.Peer-Reviewed Original ResearchMeSH KeywordsAntiviral AgentsFemaleHepatitis B e AntigensHepatitis B Surface AntigensHepatitis B virusHepatitis B, ChronicHumansInfant, NewbornInfectious Disease Transmission, VerticalNetwork Meta-AnalysisPregnancyPregnancy Complications, InfectiousRandomized Controlled Trials as TopicTelbivudineThymidineViral LoadConceptsHepatitis B virusClinical trialsVertical transmissionSeropositive mothersB virusAntiviral drugsComparative efficacyHepatitis B e antigenEfficacy of tenofovirHepatitis B immunizationIndirect treatment comparisonHigh viral loadHBV infectionIntrauterine transmissionHepatitis BAntiviral therapyB immunizationE antigenThird trimesterViral loadChinese patientsGravid motherAbstractTextComprehensive searchTreatment comparisons
2014
Hepatitis B vaccination for reducing morbidity and mortality in persons with HIV infection
Okwen MP, Reid S, Njei B, Mbuagbaw L. Hepatitis B vaccination for reducing morbidity and mortality in persons with HIV infection. Cochrane Database Of Systematic Reviews 2014, 10: cd009886. PMID: 25300375, PMCID: PMC4830339, DOI: 10.1002/14651858.cd009886.pub2.Peer-Reviewed Original ResearchMeSH KeywordsAnti-HIV AgentsHepatitis BHepatitis B VaccinesHIV InfectionsHumansRandomized Controlled Trials as TopicVaccinationConceptsHepatitis B vaccineB vaccineAntiretroviral therapyHepatitis BHumoral responseStandard hepatitis B vaccineHepatitis B virus vaccineHepatitis B infectionHepatitis B vaccinationB virus vaccineLong-term efficacyAdequate humoral responseHigh prevalence areasRoute of administrationRoute of infectionSystematic side effectsEnglish-language databasesB vaccinationB infectionHIV infectionReview authorsDATA COLLECTIONDifferent regimensImmune statusTerm efficacy