Featured Publications
Association of Non-Cigarette Tobacco Advertisements and Racial Discrimination With Non-Cigarette Tobacco Product Use Among Black Adults
Jackson A, Fleischli ME, Haeny A, Rose SW, Fagan P, Krishnan-Sarin S, Gerrard M, Gibbons FX. Association of Non-Cigarette Tobacco Advertisements and Racial Discrimination With Non-Cigarette Tobacco Product Use Among Black Adults. Nicotine & Tobacco Research 2022, 25: 781-787. PMID: 36169563, PMCID: PMC10032198, DOI: 10.1093/ntr/ntac226.Peer-Reviewed Original ResearchConceptsNon-cigarette tobacco product useNon-cigarette tobacco productsTobacco product useBlack adultsTobacco productsAdvertisement exposureCigarette useProduct usePast monthSeparate logistic regression modelsLarge cigarsTobacco-related health disparitiesCommunity Health StudyLogistic regression modelsTobacco advertisement exposurePast-month useHigher oddsSmokeless tobaccoDissolvable tobaccoHealth StudyUse of cigarillosHealth disparitiesE-cigarettesFiltered cigarsMonth useExamining the potential role of e-cigarettes to reduce health disparities associated with menthol cigarette use: Characterizing e-cigarette use, flavors, and reasons for use among US adults smoking menthol cigarettes
Bold KW, Buta E, Simon P, Gueorguieva R, Jackson A, Suttiratana SC, Krishnan-Sarin S, O'Malley SS. Examining the potential role of e-cigarettes to reduce health disparities associated with menthol cigarette use: Characterizing e-cigarette use, flavors, and reasons for use among US adults smoking menthol cigarettes. Drug And Alcohol Dependence 2022, 236: 109475. PMID: 35594642, PMCID: PMC9248755, DOI: 10.1016/j.drugalcdep.2022.109475.Peer-Reviewed Original ResearchDrug and alcohol treatment utilization and barriers among Black, American Indian/Alaskan Native, Latine, Asian/Pacific Islander/Native Hawaiian, and White adults: Findings from NESARC-III
Haeny AM, Oluwoye O, Cruz R, Iheanacho T, Jackson AB, Fisher S, Crouch M, O'Malley S. Drug and alcohol treatment utilization and barriers among Black, American Indian/Alaskan Native, Latine, Asian/Pacific Islander/Native Hawaiian, and White adults: Findings from NESARC-III. Journal Of Substance Use And Addiction Treatment 2021, 131: 108569. PMID: 34393011, PMCID: PMC9084614, DOI: 10.1016/j.jsat.2021.108569.Peer-Reviewed Original ResearchConceptsAI/AN adultsAlcohol treatment utilizationAI/ANsTreatment utilizationAlcohol use disorderWhite adultsBlack adultsDUD treatmentLifetime alcohol use disorderAmerican Indians/Alaska NativesAmerican Indian/Alaskan NativeHealth care professionalsNational Epidemiological SurveyEthnic groupsNative HawaiiansOutpatient programEpidemiological dataCare professionalsUse disordersAUD treatmentEpidemiological surveySecondary analysisSocial determinantsRelated conditionsNESARC-IIIInfluence of Menthol and Green Apple E-Liquids Containing Different Nicotine Concentrations Among Youth E-Cigarette Users
Jackson A, Green B, Erythropel HC, Kong G, Cavallo DA, Eid T, Gueorguieva R, Buta E, O’Malley S, Krishnan-Sarin S. Influence of Menthol and Green Apple E-Liquids Containing Different Nicotine Concentrations Among Youth E-Cigarette Users. Experimental And Clinical Psychopharmacology 2021, 29: 355-365. PMID: 32297782, PMCID: PMC7572568, DOI: 10.1037/pha0000368.Peer-Reviewed Original ResearchPharmacological modulation of the α7 nicotinic acetylcholine receptor in a mouse model of mecamylamine-precipitated nicotine withdrawal
Jackson A, Papke RL, Damaj MI. Pharmacological modulation of the α7 nicotinic acetylcholine receptor in a mouse model of mecamylamine-precipitated nicotine withdrawal. Psychopharmacology 2018, 235: 1897-1905. PMID: 29549391, PMCID: PMC6015775, DOI: 10.1007/s00213-018-4879-7.Peer-Reviewed Original ResearchConceptsPositive allosteric modulatorsΑ7 nicotinic acetylcholine receptorMecamylamine-precipitated nicotine withdrawalNicotine withdrawal behaviorsNicotine withdrawalNicotinic acetylcholine receptorsSomatic signsPharmacological modulationNon-selective nAChR antagonist mecamylamineAcetylcholine receptorsNicotine withdrawal-induced hyperalgesiaWithdrawal-induced hyperalgesiaDose-related fashionNicotine withdrawal signsNAChR antagonist mecamylamineAnxiety-like behaviorAntagonist mecamylamineWithdrawal signsPreclinical dataNicotine rewardΑ7 nAChRsAgonist PNU282987Mouse modelWithdrawal behaviorAllosteric modulators
2024
W36 Cooling Flavors Use and E-Cigarette Nicotine Dependence Among Youth
Li W, Davis D, Bold K, Camenga D, Jackson A, Kong G, Lee J, Morean M, Sharma A, Krishnan-Sarin S. W36 Cooling Flavors Use and E-Cigarette Nicotine Dependence Among Youth. Drug And Alcohol Dependence 2024, 260: 110654. DOI: 10.1016/j.drugalcdep.2023.110654.Peer-Reviewed Original Research
2023
Association of racial discrimination in health care settings and use of electronic cigarettes to quit smoking among Black adults
Jackson A, Gibbons F, Fleischli M, Haeny A, Bold K, Suttiratana S, Fagan P, Krishnan-Sarin S, Gerrard M. Association of racial discrimination in health care settings and use of electronic cigarettes to quit smoking among Black adults. Journal Of Substance Use And Addiction Treatment 2023, 155: 208985. PMID: 36822270, PMCID: PMC10442461, DOI: 10.1016/j.josat.2023.208985.Peer-Reviewed Original ResearchConceptsCigarette cessationHealth care settingsE-cigarettesBlack adultsHealth careCare settingsSmoking cessation practicesSmoking cessation methodsTobacco-related diseasesHealth insurance statusHealth care professionalsAge of onsetCommunity Health StudyCessation practicesSmoking cessationCessation aidInsurance statusCessation methodsSeparate logistic regressionsCurrent treatmentHealth StudyCare professionalsCigarette useElectronic cigarettesLogistic regressionThe first nicotine product tried is associated with current multiple nicotine product use and nicotine dependence among a nationally representative sample of U.S. youths
Simon P, Buta E, Jackson A, Camenga D, Kong G, Morean M, Bold K, Davis D, Krishnan-Sarin S, Gueorguieva R. The first nicotine product tried is associated with current multiple nicotine product use and nicotine dependence among a nationally representative sample of U.S. youths. Preventive Medicine 2023, 169: 107437. PMID: 36731754, PMCID: PMC10507373, DOI: 10.1016/j.ypmed.2023.107437.Peer-Reviewed Original ResearchConceptsNicotine product useSymptoms of dependenceNicotine dependenceMultiple product useSmokeless tobaccoNicotine productsProduct useSeparate multinomial logistic regression modelsHealth Study Waves 1Wave 1Smokeless tobacco usersHigher nicotine dependence scoresNicotine dependence scoresDemographic factorsLogistic regression modelsMultinomial logistic regression modelsMultivariable modelTobacco usersHigh riskDependence scoresSymptomsGreater likelihoodUse statusWave 4Regression models
2022
Editorial: Pharmacological and behavioral effects of added flavorants on tobacco addiction
Wickham R, Henderson B, Jackson A, Kabbani N. Editorial: Pharmacological and behavioral effects of added flavorants on tobacco addiction. Frontiers In Neuroscience 2022, 16: 1100476. PMID: 36545537, PMCID: PMC9762152, DOI: 10.3389/fnins.2022.1100476.Peer-Reviewed Original ResearchPharmacological characterization of 5-iodo-A-85380, a β2-selective nicotinic receptor agonist, in mice
Akinola LS, Bagdas D, Alkhlaif Y, Jackson A, Gurdap CO, Rahimpour E, Carroll FI, Papke RL, Damaj MI. Pharmacological characterization of 5-iodo-A-85380, a β2-selective nicotinic receptor agonist, in mice. Journal Of Psychopharmacology 2022, 36: 1280-1293. PMID: 36321267, PMCID: PMC9817006, DOI: 10.1177/02698811221132214.Peer-Reviewed Original ResearchConceptsNicotinic receptor agonistsReceptor agonistNicotinic acetylcholine receptorsLow sensitivityPharmacological characterizationΑ4β2 receptorsNicotine dependenceNicotinic subunitsPlace preferenceΑ4β2 nAChRsAcetylcholine receptorsPartial agonistFull agonistAgonistsDifferential efficacyBehavioral effectsNeurodegenerative diseasesSubtypesPathological conditionsNAChRsPotential targetPotential roleHypothermiaReceptorsΑ6Use and Product Characteristics of “Tobacco Free Nicotine” E-Cigarettes Among Young Adults
Davis DR, Bold KW, Camenga D, Kong G, Jackson A, Lee J, Rajesh-Kumar L, Krishnan-Sarin S, Morean ME. Use and Product Characteristics of “Tobacco Free Nicotine” E-Cigarettes Among Young Adults. Nicotine & Tobacco Research 2022, 25: 379-385. PMID: 35913677, PMCID: PMC9910142, DOI: 10.1093/ntr/ntac188.Peer-Reviewed Original ResearchConceptsE-cigarette useFrequent e-cigarette useE-cigarettesYoung adultsAdjusted modelMore frequent e-cigarette useNicotine pouchesMultivariable adjusted modelsE-cigarette use statusNicotine e-cigarettesLogistic regression modelsBinary logistic regression modelRace/ethnicityU.S. young adultsOnset ageYounger ageBivariate comparisonsNicotine concentrationsTobacco productsAlcohol useAdultsFree nicotineUse statusLifetime frequencyLifetime e-cigarette useGenotypic Differences in the Effects of Menthol on Nicotine Intake and Preference in Mice
Akinola LS, Rahman Y, Ondo O, Gonzales J, Bagdas D, Jackson A, Davidson-Wert N, Damaj MI. Genotypic Differences in the Effects of Menthol on Nicotine Intake and Preference in Mice. Frontiers In Neuroscience 2022, 16: 905330. PMID: 35769694, PMCID: PMC9234577, DOI: 10.3389/fnins.2022.905330.Peer-Reviewed Original ResearchOral nicotine consumptionEffect of mentholD2J miceMenthol effectsNicotine consumptionΑ7 nAChRsDifferential effectsTwo-bottle choiceTAAR1 geneOral aversionC57BL/6J miceNicotine rewardSystemic administrationNicotine intakeDBA/2J miceB6J micePharmacological responseNicotine addictionGenotype-specific mechanismsNicotine concentrationsMiceMouse strainsBasal preferenceGenetic factorsNicotineAssociation of youth impulsivity and use of e-cigarette devices, flavors, and frequency of use
Davis DR, Bold KW, Morean ME, Kong G, Jackson A, Simon P, Rajesh-Kumar L, Krishnan-Sarin S. Association of youth impulsivity and use of e-cigarette devices, flavors, and frequency of use. Addictive Behaviors 2022, 134: 107386. PMID: 35809413, PMCID: PMC10243516, DOI: 10.1016/j.addbeh.2022.107386.Peer-Reviewed Original ResearchCannabis use among youth who vape nicotine E-cigarettes: A qualitative analysis
Davis DR, Bold KW, Kong G, Cavallo DA, Jackson A, Krishnan-Sarin S. Cannabis use among youth who vape nicotine E-cigarettes: A qualitative analysis. Drug And Alcohol Dependence 2022, 234: 109413. PMID: 35339972, PMCID: PMC9018562, DOI: 10.1016/j.drugalcdep.2022.109413.Peer-Reviewed Original ResearchConceptsE-cigarette useE-cigarettesCannabis useHealth concernPsychoactive effectsStrong psychoactive effectsNicotine e-cigarettesFocus groupsPast-month e-cigarette usePatterns of cannabisCessation programmingSecondary data analysisNicotine productsStudy aimCannabisNicotineNicotine vapingGroupReportDual use
2021
Psychometric Evaluation of the Short-Form Vaping Consequences Questionnaire for Use With High School Adolescents Who Use and Do Not Use E-cigarettes
Morean ME, Davis DR, Bold KW, Kong G, Jackson A, Lee J, Kumar L, Krishnan-Sarin S. Psychometric Evaluation of the Short-Form Vaping Consequences Questionnaire for Use With High School Adolescents Who Use and Do Not Use E-cigarettes. Nicotine & Tobacco Research 2021, 24: 699-709. PMID: 34791432, PMCID: PMC8962724, DOI: 10.1093/ntr/ntab237.Peer-Reviewed Original ResearchSchool-based E-cigarette cessation programs: What do youth want?
Bold K, Kong G, Cavallo D, Davis D, Jackson A, Krishnan-Sarin S. School-based E-cigarette cessation programs: What do youth want? Addictive Behaviors 2021, 125: 107167. PMID: 34753093, PMCID: PMC8629945, DOI: 10.1016/j.addbeh.2021.107167.Peer-Reviewed Original ResearchConceptsConcentration/attentionCessation programsQualitative themesHigh school youthSchool youthIntervention developmentYouthE-cigarette usePersonal anecdotesFocus groupsCurrent e-cigarette usersRewardPerceptionDeductive approachSkillsFall 2019AbstinenceApathyInaccurate reportingThemesProgramEmbarrassmentE-cigarette usersAttentionAssessing knowledge, attitude, practice and training related to COVID-19: a cross-sectional survey of frontline healthcare workers in Nigeria
Iheanacho T, Stefanovics E, Okoro UG, Anyaehie UE, Njoku PO, Adimekwe AI, Ibediro K, Stefanovics GA, Haeny A, Jackson A, Unamba NN, Isiguzo G, Chukwu CC, Anyaehie UB, Mbam TT, Osy-Eneze C, Ibezim EO. Assessing knowledge, attitude, practice and training related to COVID-19: a cross-sectional survey of frontline healthcare workers in Nigeria. BMJ Open 2021, 11: e050138. PMID: 34580097, PMCID: PMC8478584, DOI: 10.1136/bmjopen-2021-050138.Peer-Reviewed Original ResearchConceptsFrontline healthcare workersHealthcare workersCOVID-19 KAPCross-sectional surveyCOVID-19Non-physician healthcare workersTertiary care settingGroup differencesDirect clinical contactLaboratory professionalsExploratory factor analysisSignificant group differencesCare settingsHealth workersClinical contactIndependent factorsHealth educationHealthcare settingsMedical laboratory scientistsClinical laboratory professionalsTraining needsNursesFactor 1Pharmaceutical workersFactor 4Cooling e-cigarette flavors and the association with e-cigarette use among a sample of high school students
Davis DR, Morean ME, Bold KW, Camenga D, Kong G, Jackson A, Simon P, Krishnan-Sarin S. Cooling e-cigarette flavors and the association with e-cigarette use among a sample of high school students. PLOS ONE 2021, 16: e0256844. PMID: 34469460, PMCID: PMC8409641, DOI: 10.1371/journal.pone.0256844.Peer-Reviewed Original ResearchIndividual Differences in the Associations Between Risk Factors for Alcohol Use Disorder and Alcohol Use-Related Outcomes
Haeny AM, Gueorguieva R, Jackson A, Morean ME, Krishnan-Sarin S, DeMartini KS, Pearlson GD, Anticevic A, Krystal JH, O’Malley S. Individual Differences in the Associations Between Risk Factors for Alcohol Use Disorder and Alcohol Use-Related Outcomes. Psychology Of Addictive Behaviors 2021, 35: 501-513. PMID: 34110841, PMCID: PMC9211405, DOI: 10.1037/adb0000733.Peer-Reviewed Original ResearchPotentiation of (α4)2(β2)3, but not (α4)3(β2)2, nicotinic acetylcholine receptors reduces nicotine self-administration and withdrawal symptoms
Hamouda AK, Bautista MR, Akinola LS, Alkhlaif Y, Jackson A, Carper M, Toma WB, Garai S, Chen YC, Thakur GA, Fowler CD, Damaj MI. Potentiation of (α4)2(β2)3, but not (α4)3(β2)2, nicotinic acetylcholine receptors reduces nicotine self-administration and withdrawal symptoms. Neuropharmacology 2021, 190: 108568. PMID: 33878302, PMCID: PMC8169606, DOI: 10.1016/j.neuropharm.2021.108568.Peer-Reviewed Original ResearchConceptsPositive allosteric modulatorsWithdrawal symptomsHypothermic effectMale miceAntinociceptive effectΑ4β2 nAChRsNicotine withdrawal-induced hyperalgesiaNAChR isoformsNicotine's antinociceptive effectsWithdrawal-induced hyperalgesiaNicotine withdrawal symptomsNicotine addiction treatmentAnxiety-like behaviorNicotinic acetylcholine receptorsDose-dependent mannerNociceptive responsesNicotine withdrawalNicotine intakeSomatic signsNicotine abstinencePharmacological effectsNicotine useAcetylcholine receptorsAffective symptomsPathophysiological processes