Impact of modulation of the α7 nicotinic acetylcholine receptor on nicotine reward in the mouse conditioned place preference test
Jackson A, Alkhlaif Y, Papke RL, Brunzell DH, Damaj MI. Impact of modulation of the α7 nicotinic acetylcholine receptor on nicotine reward in the mouse conditioned place preference test. Psychopharmacology 2019, 236: 3593-3599. PMID: 31302720, PMCID: PMC6895411, DOI: 10.1007/s00213-019-05331-y.Peer-Reviewed Original ResearchConceptsPositive allosteric modulatorsΑ7 nicotinic acetylcholine receptorNicotine rewardNicotine CPPNicotinic acetylcholine receptorsΑ7 nAChRsAgonist PNU282987Acetylcholine receptorsPlace preference testMorphine CPPPharmacological modulationPharmacological agentsCPP paradigmPlace preferenceAllosteric modulatorsPNU282987MethodsThe effectsΑ7Beneficial effectsMiceSilent agonistPNU120596ObjectivesThis studyNS1738NS6740