2021
Delays in antibiotic redosing: Association with inpatient mortality and risk factors for delay
Kemmler CB, Sangal RB, Rothenberg C, Li SX, Shofer FS, Abella BS, Venkatesh AK, Foster SD. Delays in antibiotic redosing: Association with inpatient mortality and risk factors for delay. The American Journal Of Emergency Medicine 2021, 46: 63-69. PMID: 33735698, DOI: 10.1016/j.ajem.2021.02.058.Peer-Reviewed Original ResearchConceptsSecond dose administrationEmergency departmentDose administrationRisk factorsEmergency Severity IndexHospital mortalityFirst doseSecond doseED boardingAntibiotic dosesEnd-stage renal diseaseExtremes of weightHigh acuity presentationsRetrospective cohort studyStage renal diseaseWorse clinical outcomesSerious bacterial infectionsOdds of delayEarly hospital courseSingle healthcare systemAntibiotic redosingDosing intervalHospital courseCohort studyInpatient mortality
2013
Time to antibiotics for septic shock: evaluating a proposed performance measure
Venkatesh AK, Avula U, Bartimus H, Reif J, Schmidt MJ, Powell ES. Time to antibiotics for septic shock: evaluating a proposed performance measure. The American Journal Of Emergency Medicine 2013, 31: 680-683. PMID: 23380106, DOI: 10.1016/j.ajem.2012.12.008.Peer-Reviewed Original ResearchConceptsHours of arrivalSeptic shockED arrivalAntibiotic administrationConsecutive ED patientsSeptic shock definitionSeptic shock recognitionEmergency department arrivalCross-sectional studyClinical coursePrimary outcomeAcademic EDED patientsMedian timeShock recognitionVariable progressionPatientsInternational guidelinesShock definitionAntibioticsTime courseAdministrationHours