2024
Neuropsychiatric complications of coronavirus disease 2019: Mount Sinai Health System cohort study
Gururangan K, Peschansky V, Van Hyfte G, Agarwal P, Blank L, Mathew B, Goldstein J, Kwon C, McCarthy L, Cohen A, Chan A, Deng P, Dhamoon M, Gutzwiller E, Hao Q, He C, Klenofsky B, Lemus H, Marcuse L, Navis A, Heredia Nunez W, Luckey M, Schorr E, Singh A, Tantillo G, Ufongene C, Young J, Balchandani P, Festa J, Naasan G, Charney A, Nadkarni G, Jetté N. Neuropsychiatric complications of coronavirus disease 2019: Mount Sinai Health System cohort study. Journal Of Neurology 2024, 271: 3991-4007. PMID: 38656620, DOI: 10.1007/s00415-024-12370-9.Peer-Reviewed Original ResearchConceptsIn-hospital mortalityAssociated with lower oddsHigher odds of mortalityResultsOur study cohortElectronic medical record databaseChart reviewNeuropsychiatric complicationsNew York City health systemOdds of mortalityAssociated with in-hospital mortalityMultivariate logistic regressionMedical record databaseHealth systemLower oddsHigher oddsIndividual chart reviewSerum inflammatory marker levelsCohort studyPre-existing comorbiditiesRecord databaseCOVID-19Logistic regressionTreated with anticoagulationInflammatory marker levelsComplication of coronavirus diseaseHealth care access, psychosocial outcomes and mental health in adults living with epilepsy during the COVID-19 pandemic
Mc Carthy L, Mathew B, Blank L, Van Hyfte G, Gotlieb E, Goldstein J, Agarwal P, Kwon C, Singh A, Fields M, Marcuse L, Yoo J, Sivarak E, Gururangan K, Navis A, Jetté N. Health care access, psychosocial outcomes and mental health in adults living with epilepsy during the COVID-19 pandemic. Epilepsy & Behavior 2024, 151: 109617. PMID: 38219607, DOI: 10.1016/j.yebeh.2023.109617.Peer-Reviewed Original ResearchConceptsPatient Health Questionnaire-9Generalized Anxiety Disorder-7Psychosocial outcomesMental healthHealthcare accessCancelled visitsCross-sectional study of adultsHealth care accessCOVID-19 pandemicMental health comorbiditiesPoor mental healthSocial support issuesPoor psychosocial outcomesSymptoms of anxietyCross-sectional studyStudy of adultsCare accessPsychosocial supportHealth comorbiditiesModerate/severe depressionHealth systemTelehealth visitsNeurological carePLWEStandardized questionnaire
2023
Older adults with epilepsy and COVID-19: Outcomes in a multi-hospital health system
Ufongene C, Van Hyfte G, Agarwal P, Goldstein J, Mathew B, Navis A, McCarthy L, Kwon C, Gururangan K, Balchandani P, Marcuse L, Naasan G, Singh A, Young J, Charney A, Nadkarni G, Jette N, Blank L, Group S. Older adults with epilepsy and COVID-19: Outcomes in a multi-hospital health system. Seizure 2023, 114: 33-39. PMID: 38039805, PMCID: PMC10841585, DOI: 10.1016/j.seizure.2023.11.018.Peer-Reviewed Original ResearchConceptsInternational Classification of DiseasesLength of stayOlder adultsDischarge dispositionHigher in-hospital mortalityHealth systemIn-hospital deathIn-hospital mortalityMulti-hospital health systemOdds of in-hospital deathAssociated with increased oddsAssociated with increased odds of in-hospital deathNew York health systemMultivariate logistic regression modelClassification of DiseasesConsecutive older patientsAssociated with higher in-hospital mortalityLogistic regression modelsCompare in-hospital outcomesFactors associated with mortalityNon-routine discharge dispositionAssociated with higher ratesOlder peopleInternational ClassificationAdmitted with COVID-19In‐hospital outcomes in patients with and without epilepsy diagnosed with COVID‐19—A cohort study
Ufongene C, Van Hyfte G, Agarwal P, Blank L, Goldstein J, Mathew B, Lin J, Navis A, McCarthy L, Gururangan K, Peschansky V, Kwon C, Cohen A, Chan A, Dhamoon M, Deng P, Gutzwiller E, Hao Q, He C, Nunez W, Klenofsky B, Lemus H, Marcuse L, Roberts M, Schorr E, Singh A, Tantillo G, Young J, Balchandani P, Festa J, Naasan G, Charney A, Nadkarni G, Jetté N. In‐hospital outcomes in patients with and without epilepsy diagnosed with COVID‐19—A cohort study. Epilepsia 2023, 64: 2725-2737. PMID: 37452760, DOI: 10.1111/epi.17715.Peer-Reviewed Original ResearchConceptsLength of stayNon-routine dischargeCharlson Comorbidity IndexIn-hospital outcomesHigher Charlson comorbidity indexFactors associated with higher oddsIntensive care unitInternational Classification of DiseasesOlder ageAssociated with COVID-19 mortalityRegression modelsClassification of DiseasesDecreased LOSLonger length of stayLogistic regression modelsAssociated with mortalityHealth systemOrdinary least squares regression modelsCOVID-19 mortalityOlder adultsRetrospective study of patientsInternational ClassificationHigher oddsMulticenter health systemEvaluate in-hospital outcomesNeuroimaging findings and neurological manifestations in hospitalized COVID-19 patients: Impact of cancer and ventilatory support status
McCarthy L, Khegai O, Goldstein J, Belani P, Pawha P, Kihira S, Mathew B, Gururangan K, Hao Q, Singh A, Navis A, Delman B, Jette N, Balchandani P. Neuroimaging findings and neurological manifestations in hospitalized COVID-19 patients: Impact of cancer and ventilatory support status. PLOS ONE 2023, 18: e0283614. PMID: 36961861, PMCID: PMC10038284, DOI: 10.1371/journal.pone.0283614.Peer-Reviewed Original ResearchConceptsHospitalized COVID-19 patientsMagnetic resonance imagingVentilatory supportNeurological manifestationsCOVID-19 patientsNeuroimaging findingsSupport statusImpact of cancerPolymerase chain reaction-confirmed COVID-19Mount Sinai Health SystemNon-cancer patientsAssociated with neurological manifestationsRetrospective observational studySinai Health SystemClinical neurological manifestationsHealth systemCentral nervous systemCOVID-19 cohortMorbidity associated with COVID-19Cancer statusAcute/subacute infarctionProthrombotic stateCOVID-19Systemic illnessFocal weakness