1997
Ligand-dependent development of the endothelial and hemopoietic lineages from embryonic mesodermal cells expressing vascular endothelial growth factor receptor 2
Eichmann A, Corbel C, Nataf V, Vaigot P, Bréant C, Le Douarin N. Ligand-dependent development of the endothelial and hemopoietic lineages from embryonic mesodermal cells expressing vascular endothelial growth factor receptor 2. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 5141-5146. PMID: 9144204, PMCID: PMC24645, DOI: 10.1073/pnas.94.10.5141.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, MonoclonalCell DifferentiationChick EmbryoEndothelial Growth FactorsEndothelium, VascularGastrulaHematopoietic Stem CellsHomozygoteLigandsLymphokinesMesodermMiceMice, Inbred BALB CMice, KnockoutQuailReceptor Protein-Tyrosine KinasesReceptors, Growth FactorReceptors, Vascular Endothelial Growth FactorVascular Endothelial Growth Factor AVascular Endothelial Growth FactorsConceptsVascular endothelial growth factor receptor 2VEGFR2 ligandsEndothelial growth factor receptor 2Embryonic mesodermal cellsVascular endothelial lineageHemopoietic cellsDevelopmental decisionsGastrulation stageHomozygous null miceMesodermal cellsAbsence of VEGFGene productsGene targetingNull mutationEndothelial lineageHemopoietic differentiationExtracellular domainClonal culturesLineagesHemopoietic lineagesEndothelial differentiationEndothelial cell coloniesCell coloniesCell microenvironmentGrowth factor receptor 2
1994
Distinct developmental expression of a new avian fibroblast growth factor receptor
Marcelle C, Eichmann A, Halevy O, Bréant C, Le Douarin N. Distinct developmental expression of a new avian fibroblast growth factor receptor. Development 1994, 120: 683-694. PMID: 8162862, DOI: 10.1242/dev.120.3.683.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBase SequenceBlotting, NorthernChick EmbryoCloning, MolecularCoturnixFibroblast Growth Factor 2GastrulaGene ExpressionIn Situ HybridizationMolecular Sequence DataMusclesPolymerase Chain ReactionReceptor Protein-Tyrosine KinasesReceptor, Fibroblast Growth Factor, Type 4Receptors, Fibroblast Growth FactorConceptsFibroblast growth factor receptorGrowth factor receptorMesoderm-derived structuresSkeletal muscle lineageFibroblast growth factor receptor (FGFR) familySatellite cellsStage-specific mannerDistinct developmental expressionFactor receptorNew memberIg-like domainsEarly myotomeGrowth factor receptor familyPattern of expressionSkeletal muscleEmbryonic RNAPrimitive streak stageLateral epiblastMuscle lineageDays of developmentFactor receptor familyPrimary transcriptEarly avian developmentAvian developmentFibroblast growth factor