2004
The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system
Lu X, le Noble F, Yuan L, Jiang Q, de Lafarge B, Sugiyama D, Bréant C, Claes F, De Smet F, Thomas JL, Autiero M, Carmeliet P, Tessier-Lavigne M, Eichmann A. The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system. Nature 2004, 432: 179-186. PMID: 15510105, DOI: 10.1038/nature03080.Peer-Reviewed Original ResearchConceptsNetrin receptor UNC5BEndothelial tip cell filopodiaTip cell filopodiaReceptor UNC5BEndothelial tip cellsVascular systemNetrin-1aTip cellsEndothelial cellsProper wiringAxon guidanceCell filopodiaNetrin receptorsGuidance eventsFilopodial retractionMorphogenesisUNC5BVessel branchingAberrant extensionAnatomical similaritiesNetrin-1CellsZebrafishGenesGuidance function
2001
Development of the avian lymphatic system
Wilting J, Papoutsi M, Othman‐Hassan K, Rodriguez‐Niedenführ M, Pröls F, Tomarev S, Eichmann A. Development of the avian lymphatic system. Microscopy Research And Technique 2001, 55: 81-91. PMID: 11596153, DOI: 10.1002/jemt.1159.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBirdsChick EmbryoEndothelial Growth FactorsEndothelium, LymphaticHomeodomain ProteinsImmunohistochemistryIn Situ HybridizationLymphatic SystemQuailReceptor Protein-Tyrosine KinasesReceptors, Growth FactorReceptors, Vascular Endothelial Growth FactorTumor Suppressor ProteinsVascular Endothelial Growth Factor CEndogenous origin of the lymphatics in the avian chorioallantoic membrane
Papoutsi M, Tomarev S, Eichmann A, Pröls F, Christ B, Wilting J. Endogenous origin of the lymphatics in the avian chorioallantoic membrane. Developmental Dynamics 2001, 222: 238-251. PMID: 11668601, DOI: 10.1002/dvdy.1187.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell DifferentiationChick EmbryoChickensChimeraChorionEndothelial Growth FactorsEndothelium, LymphaticGene Expression Regulation, DevelopmentalHomeodomain ProteinsMesodermQuailReceptor Protein-Tyrosine KinasesReceptors, Growth FactorTumor Suppressor ProteinsVascular Endothelial Growth Factor CVascular Endothelial Growth Factor Receptor-3ConceptsVascular endothelial growth factor receptor 3Allantoic budSplanchnic mesodermAllantoic mesodermHematopoietic cellsMesenchymal cellsQuail embryosChorioallantoic membraneEndothelial cellsGrowth factor receptor 3Intraembryonic sitesBlood islandsMesodermAllantoic epitheliumEmbryosEndothelial networksBudsAvian chorioallantoic membraneDay 4 embryosImportant functionsMRNA probesLymphangiogenic potentialLymphatic endotheliumCAM developmentChick embryos