1988
Ca2+/calmodulin-dependent protein kinase II: identification of threonine-286 as the autophosphorylation site in the alpha subunit associated with the generation of Ca2+-independent activity.
Thiel G, Czernik AJ, Gorelick F, Nairn AC, Greengard P. Ca2+/calmodulin-dependent protein kinase II: identification of threonine-286 as the autophosphorylation site in the alpha subunit associated with the generation of Ca2+-independent activity. Proceedings Of The National Academy Of Sciences Of The United States Of America 1988, 85: 6337-6341. PMID: 2842767, PMCID: PMC281965, DOI: 10.1073/pnas.85.17.6337.Peer-Reviewed Original ResearchConceptsBeta/beta' subunitsAlpha subunitThr-286Beta subunitDependent protein kinase IIProtein kinase IIAutophosphorylation sitesThreonine residuesMajor phosphopeptideNaDodSO4/PAGEPhosphorylated residuesCyanogen bromide peptidesConsensus sequenceKinase IIIndependent activityThermolytic phosphopeptidesPrimary structureGas-phase Edman degradationGeneration of Ca2Edman degradationAutophosphorylationSubunitsThreonine-286Amino acidsAsp-Xaa
1985
Calcium-Regulated Protein Phosphorylation in Mammalian Brain
Walaas S, Nairn A. Calcium-Regulated Protein Phosphorylation in Mammalian Brain. 1985, 238-264. DOI: 10.1007/978-3-642-70070-5_12.Peer-Reviewed Original ResearchCentral nervous systemExcitation-secretion couplingNerve cell functionSkeletal muscle contractionPeripheral nervesGeneration of Ca2Nervous systemImportant intracellular messengerMammalian brainNeurotransmitter synthesisMuscle contractionProtein phosphorylationCell functionMammalian tissuesMitochondrial respirationIntracellular messengerEndocytotic phenomenonSecretory glandsIon channelsCa2NerveBrainGlycogenolysis