2023
Spontaneous vesicoureteral reflux resolution curves based on ureteral diameter ratio
Arlen A, Leong T, Kirsch A, Cooper C. Spontaneous vesicoureteral reflux resolution curves based on ureteral diameter ratio. Journal Of Pediatric Urology 2023, 19: 468.e1-468.e6. PMID: 37188603, DOI: 10.1016/j.jpurol.2023.04.028.Peer-Reviewed Original ResearchConceptsUreteral diameter ratioUrinary tract infectionPrimary vesicoureteral refluxVesicoureteral refluxSpontaneous resolutionRisk groupsBreakthrough febrile urinary tract infectionDistal ureteral diameter ratioFebrile urinary tract infectionLargest ureteral diameterObjective prognostic informationGrade of refluxHigh-risk patientsLow-risk patientsHigh-risk groupLow-risk groupLow-risk childrenVUR resolutionPrimary refluxProphylactic antibioticsVUR gradeConservative managementPersistent refluxRisk patientsTract infections
2017
Role of body mass index in school-aged children with lower urinary tract dysfunction: Does weight classification predict treatment outcome?
Arlen AM, Cooper CS, Leong T. Role of body mass index in school-aged children with lower urinary tract dysfunction: Does weight classification predict treatment outcome? Journal Of Pediatric Urology 2017, 13: 454.e1-454.e5. PMID: 28483466, DOI: 10.1016/j.jpurol.2017.03.033.Peer-Reviewed Original ResearchConceptsBody mass indexBladder-bowel dysfunctionLower urinary tract dysfunctionUrinary tract dysfunctionUrinary tract infectionSchool-aged childrenTreatment outcomesTreatment responseLUT dysfunctionTract dysfunctionTract infectionsTreatment failureMass indexElevated body mass indexLower urinary tract symptomsDetrusor-sphincter dyssynergiaUrinary tract symptomsAdditional treatment modalitiesComplete treatment responseMajor health concernBowel programPsychologic comorbiditiesSphincter dyssynergiaUrology referralTract symptoms
2016
Delayed upper tract drainage on voiding cystourethrogram may not be associated with increased risk of urinary tract infection in children with vesicoureteral reflux
Garcia-Roig M, Arlen AM, Huang JH, Filimon E, Leong T, Kirsch AJ. Delayed upper tract drainage on voiding cystourethrogram may not be associated with increased risk of urinary tract infection in children with vesicoureteral reflux. Journal Of Pediatric Urology 2016, 12: 312.e1-312.e6. PMID: 27492248, DOI: 10.1016/j.jpurol.2016.04.056.Peer-Reviewed Original ResearchConceptsUpper tract drainageCulture-proven UTIsVesicoureteral refluxUTI ratesVUR gradeUTI riskRisk factorsHigh inter-observer correlationSetting of obstructionUTI risk factorsUrinary tract infectionPrimary vesicoureteral refluxPredictors of infectionAvailable prognostic informationSignificant predictorsYears of ageEndoscopic VUR treatmentHydrodistention gradeInter-observer agreementRecurrent UTIUTI incidenceVUR timingEndoscopic findingsInter-observer correlationTract infections
2014
Bladder Volume at Onset of Vesicoureteral Reflux is an Independent Risk Factor for Breakthrough Febrile Urinary Tract Infection
Alexander S, Arlen A, Storm D, Kieran K, Cooper C. Bladder Volume at Onset of Vesicoureteral Reflux is an Independent Risk Factor for Breakthrough Febrile Urinary Tract Infection. Journal Of Urology 2014, 193: 1342-1346. PMID: 25305355, DOI: 10.1016/j.juro.2014.10.002.Peer-Reviewed Original ResearchConceptsBreakthrough febrile urinary tract infectionFebrile urinary tract infectionUrinary tract infectionOnset of refluxBladder-bowel dysfunctionRisk of pyelonephritisTract infectionsVesicoureteral refluxBladder volumeReflux gradeRecurrent febrile urinary tract infectionsMedian bladder volumeIndependent risk factorAdditional prognostic informationIdentification of childrenDuration of exposureReflux onsetBladder capacityMedian followupSD agePrognostic informationRisk factorsMultivariate analysisClinical decisionInfection