2022
Recent Advances in the Rheumatic Fever and Rheumatic Heart Disease Continuum
Rwebembera J, Nascimento B, Minja N, de Loizaga S, Aliku T, dos Santos L, Galdino B, Corte L, Silva V, Chang A, Dutra W, Nunes M, Beaton A. Recent Advances in the Rheumatic Fever and Rheumatic Heart Disease Continuum. Pathogens 2022, 11: 179. PMID: 35215123, PMCID: PMC8878614, DOI: 10.3390/pathogens11020179.Peer-Reviewed Original ResearchRheumatic heart diseaseHuman immunodeficiency virusRheumatic feverLatent rheumatic heart diseaseManagement of rheumatic heart diseaseGroup A <i>Streptococcus</i>Burden of rheumatic heart diseaseSecondary antibiotic prophylaxisAntibiotic prophylaxisGAS pharyngitisEchocardiographic screeningImmunodeficiency virusDiagnostic strategiesHeart diseaseTertiary managementVaccine developmentMiddle-income countriesNarrative reviewDisease continuumRF/RHDDiseaseFeverGlobal eradicationInfectious diseasesRheumatism
2021
Clinical Outcomes, Echocardiographic Findings, and Care Quality Metrics for People Living With Human Immunodeficiency Virus (HIV) and Rheumatic Heart Disease in Uganda
Chang A, Rwebembera J, Bendavid E, Okello E, Barry M, Beaton A, Haeffele C, Webel A, Kityo C, Longenecker C. Clinical Outcomes, Echocardiographic Findings, and Care Quality Metrics for People Living With Human Immunodeficiency Virus (HIV) and Rheumatic Heart Disease in Uganda. Clinical Infectious Diseases 2021, 74: 1543-1548. PMID: 34382644, DOI: 10.1093/cid/ciab681.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusRheumatic heart diseaseEchocardiographic findingsImmunodeficiency virusHeart diseaseClinical outcomesDiagnosis of human immunodeficiency virusPrescription ratesAge- and sex-matched cohortMedication prescription ratesLongitudinal outcomes of patientsCare quality metricsOutcomes of patientsMiddle-income countriesEpidemiology of patientsSex-matched cohortAll-cause mortalityStroke/transient ischemic attackRate of strokeMedian ageClinical careCardiovascular complicationsClinical characteristicsMultivariable adjustmentConcurrent diagnosis