2022
Disease‐modifying therapies and T1 hypointense lesions in patients with multiple sclerosis: A systematic review and meta‐analysis
Valizadeh A, Fattahi M, Sadeghi M, Torbati M, Sahraian M, Azimi A. Disease‐modifying therapies and T1 hypointense lesions in patients with multiple sclerosis: A systematic review and meta‐analysis. CNS Neuroscience & Therapeutics 2022, 28: 648-657. PMID: 35218155, PMCID: PMC8981477, DOI: 10.1111/cns.13815.Peer-Reviewed Original ResearchConceptsDisease-modifying therapiesCertainty of evidenceVolumes of T1Hypointense lesionsMultiple sclerosis patientsRisk of biasRoB 2 toolT1-hypointense lesionsRandom-effects modelEffects of FDANumber of lesionsAdult patientsSclerosis patientsMultiple sclerosisComparator groupPrognostic markerObjective markersSystematic reviewLesionsMean differenceMean volumePatientsRelevant studiesHypointenseTherapy
2021
Correlation between the clinical disability and T1 hypointense lesions’ volume in cerebral magnetic resonance imaging of multiple sclerosis patients: A systematic review and meta‐analysis
Valizadeh A, Moassefi M, Barati E, Sahraian M, Aghajani F, Fattahi M. Correlation between the clinical disability and T1 hypointense lesions’ volume in cerebral magnetic resonance imaging of multiple sclerosis patients: A systematic review and meta‐analysis. CNS Neuroscience & Therapeutics 2021, 27: 1268-1280. PMID: 34605190, PMCID: PMC8504532, DOI: 10.1111/cns.13734.Peer-Reviewed Original ResearchConceptsMean volumeCerebral magnetic resonance imagingPrognosis Studies toolMultiple sclerosis patientsRisk of biasT1-hypointense lesionsRandom-effects modelMagnetic resonance imagingWeb of ScienceClinical disabilityAdult patientsCerebral MRIEDSS scoreSclerosis patientsMultiple sclerosisDisability levelHypointense lesionsSystematic reviewResonance imagingPatientsRelevant studiesStudy toolCorrelation coefficientT1EDSS