2018
Harnessing the Immunomodulatory Effects of Radiation Therapy.
Campbell AM, Decker RH. Harnessing the Immunomodulatory Effects of Radiation Therapy. Oncology 2018, 32: 370-4, cv3. PMID: 30080922.Peer-Reviewed Original ResearchConceptsImmunomodulatory effectsImmune responseImmune systemSetting of cancerSystemic immune responsesAntitumoral immune responseInnate immune systemAdaptive immune systemCell deathTumor cell deathAntitumoral immunityAntitumoral responseHypofractionated radiationRadiotherapy timingProinflammatory responsePreclinical modelsAdaptive immunityRadiation therapyClinical informationRadiation-induced cell deathDoseImmunityDeathPotential superiorityDNA damage
2007
Mini-review of conventional and hypofractionated radiation therapy combined with immunotherapy for non-small cell lung cancer
Campbell AM, Decker RH. Mini-review of conventional and hypofractionated radiation therapy combined with immunotherapy for non-small cell lung cancer. Translational Lung Cancer Research 2007, 6: 220-229. PMID: 28529904, PMCID: PMC5420539, DOI: 10.21037/tlcr.2017.03.02.Peer-Reviewed Original ResearchNon-small cell lung cancerCell lung cancerAntitumoral responseAdaptive immune systemLung cancerRadiation therapyImmune systemHypofractionated radiation therapyOngoing clinical trialsDose-fractionation schedulesAssessment of efficacyImmunogenicity of antigensIdentification of biomarkersCell deathAntigenic poolCheckpoint inhibitorsCancer vaccinesCytokine administrationClinical trialsImmunological activationFractionation schedulesRadiation-induced cell deathImmunotherapyActivation statusMonoclonal antibodies