2024
Bilateral Lesional Epilepsy
Herlopian A. Bilateral Lesional Epilepsy. 2024, 819-847. DOI: 10.1007/978-3-031-23828-4_33.Peer-Reviewed Original ResearchNon-dominant, Lesional Parieto-occipital Lobe Epilepsy
Herlopian A. Non-dominant, Lesional Parieto-occipital Lobe Epilepsy. 2024, 221-240. DOI: 10.1007/978-3-031-23828-4_11.Peer-Reviewed Original ResearchFocal cortical dysplasiaCortical dysplasiaSupratentorial cystic lesionsPost-operative outcomesInterictal epileptiform activityPredictors of outcomeAnti-seizure medicationsMechanisms of epileptogenesisVisual evoked potentialsNeocortical epilepsy surgeryResection surgeryCystic lesionsSurgical interventionEpileptiform activityDifferential diagnosisEvoked potentialsPharmacoresistant epilepsyPatient populationNeuroimaging characteristicsEpilepsy surgeryDysplasiaPatientsOccipital lobeSensorimotor cortexSurgeryDominant, Lesional Post-Traumatic Temporal Lobe Epilepsy
Herlopian A. Dominant, Lesional Post-Traumatic Temporal Lobe Epilepsy. 2024, 135-160. DOI: 10.1007/978-3-031-23828-4_7.Peer-Reviewed Original ResearchTraumatic brain injuryImprove medication complianceIntracranial monitoringPatient populationExtent of cerebral injuryAnalysis of patientsNeuroimaging modalitiesPost-traumatic epilepsyMedication adherenceMedication compliancePredictors of outcomeBrain injuryStages of epileptogenesisSurgical outcomesIctal onsetResection surgerySurgical interventionTonic seizuresCerebral injuryHistopathological analysisPatientsVisual phenomenaEpilepsyOutcomesInjuryDominant, Tumor-Related Mesial Temporal Lobe Epilepsy
Herlopian A. Dominant, Tumor-Related Mesial Temporal Lobe Epilepsy. 2024, 747-755. DOI: 10.1007/978-3-031-23828-4_30.Peer-Reviewed Original ResearchDominant, Lesional Pediatric-Onset Hemispheric Epilepsy
Knight V, Herlopian A. Dominant, Lesional Pediatric-Onset Hemispheric Epilepsy. 2024, 533-562. DOI: 10.1007/978-3-031-23828-4_22.Peer-Reviewed Original ResearchRasmussen encephalitisCerebrospinal fluid analysis findingsIctal rhythmic dischargesFocal cortical dysplasiaEpilepsia partialis continuaIctal nystagmusPediatric patientsCortical dysplasiaSurgical considerationsStatus epilepticusSurgical interventionPediatric populationCortical myoclonusRhythmic dischargesDevice placementProgressive epilepsyPatientsQuantitative electroencephalographyEncephalitisTechnical considerationsEpilepticusNystagmusNon-dominant, Lesional Posterior Quadrant Epilepsy
Herlopian A. Non-dominant, Lesional Posterior Quadrant Epilepsy. 2024, 633-652. DOI: 10.1007/978-3-031-23828-4_25.Peer-Reviewed Original ResearchArterio-venous malformationsIntracranial monitoringImpact of topiramatePosterior quadrantic epilepsyTreat pharmacoresistant epilepsySurgical outcomesTransient encephalopathyElectrographic seizuresSurgical interventionOutcome predictorsClinical significancePharmacoresistant epilepsyEpileptogenesis mechanismsEpilepsy patientsPatientsWada testAuditory hallucinationsLanguage reorganizationMalformationsEpilepsyCognitive functionOutcomesAuditory illusionTopiramateDominant, Mesial Temporal Lobe Epilepsy Due to Hippocampal Sclerosis
Herlopian A. Dominant, Mesial Temporal Lobe Epilepsy Due to Hippocampal Sclerosis. 2024, 735-745. DOI: 10.1007/978-3-031-23828-4_29.Peer-Reviewed Original ResearchHippocampal sclerosisOlfactory hallucinationsNeuropsychological outcomesTemporal lobe epilepsyMesial temporal lobe epilepsyDeep brain stimulationHippocampalVisual field defectsBrain stimulationLobe epilepsyThermoablative therapyField defectsSeizure outcomePost-ablationFebrile seizuresPharmacoresistant epilepsyPotential complicationsTherapyPatientsPalilaliaSclerosisHallucinationsHippocampusEpilepsySniffingNon-dominant, Non-lesional Mesial Temporal Lobe Epilepsy
Herlopian A, Mattson R. Non-dominant, Non-lesional Mesial Temporal Lobe Epilepsy. 2024, 63-86. DOI: 10.1007/978-3-031-23828-4_4.Peer-Reviewed Original ResearchTemporal lobe epilepsyLobe epilepsySurgical outcomesMRI-negative temporal lobe epilepsyInterictal PET scanPharmacoresistant temporal lobe epilepsyPost-operative resultsFavorable post-operative resultsTemporal lobe seizuresSlow wave activityMRI-negativePET scansHypermotor symptomsPharmacoresistant epilepsyRespiratory manifestationsNon-lesionalFronto-parietal cortexPatientsEpilepsyImpaired awarenessNon-dominant, Lesional Temporal Lobe Epilepsy
Herlopian A. Non-dominant, Lesional Temporal Lobe Epilepsy. 2024, 361-374. DOI: 10.1007/978-3-031-23828-4_16.Peer-Reviewed Original ResearchMultifocal Epilepsy Due to New-Onset Refractory Status Epilepticus
Herlopian A, Gunawardane N. Multifocal Epilepsy Due to New-Onset Refractory Status Epilepticus. 2024, 497-532. DOI: 10.1007/978-3-031-23828-4_21.Peer-Reviewed Original ResearchRefractory status epilepticusStatus epilepticusNew-onset refractory status epilepticusOnset refractory status epilepticusSuper-refractory status epilepticusSingle pulse electrical stimulationCortico-cortical evoked potentialsResponsive neurostimulation deviceNew-onsetMultifocal epilepsySurgical interventionNeuroimaging characteristicsEpilepticusPulse electrical stimulationEpileptic networkEvaluate functional connectivityPatientsCortical stimulationNeurostimulation devicesElectrical stimulationFunctional connectivityLanguage mappingStimulationDominant, Lesional Posterior Quadrant Epilepsy
Herlopian A, Tolba H, Mattson R. Dominant, Lesional Posterior Quadrant Epilepsy. 2024, 757-777. DOI: 10.1007/978-3-031-23828-4_31.Peer-Reviewed Original ResearchIctal high-frequency oscillationsPeriventricular nodular heterotopiaPredicting surgical outcomesSurgical decision-making processFocal cortical dysplasiaPropagation of seizuresInterictal epileptiform dischargesThermoablative therapyNodular heterotopiaSurgical outcomesCortical dysplasiaIctal patternsCortical malformationsEpileptiform dischargesIntracranial monitoringPharmacoresistant epilepsyClonic movementsIctal vocalizationSpeech disturbanceCephalic auraTherapyPatientsHigh-frequency oscillationsAcquired, Lesional Lennox-Gastaut Syndrome
Herlopian A. Acquired, Lesional Lennox-Gastaut Syndrome. 2024, 919-943. DOI: 10.1007/978-3-031-23828-4_37.Peer-Reviewed Original ResearchCentromedian nucleusConfirm electrode placementGeneralized atonic seizuresLennox-Gastaut syndromeCentromedian thalamic nucleusLanguage lateralizationPost-operative language deficitsRare entityLennox-GastautCorpus callosotomySurgical interventionCortical malformationsAtonic seizuresSurgical proceduresThalamic nucleiCorpus callosumEpileptic networkDeep brain stimulation devicesLanguage deficitsNeurostimulation devicesElectrode placementPatientsNeurophysiological recordingsEpilepsyLanguageNon-dominant, Lesional Frontal Lobe Epilepsy Overlapping with Motor Cortex
Herlopian A. Non-dominant, Lesional Frontal Lobe Epilepsy Overlapping with Motor Cortex. 2024, 469-496. DOI: 10.1007/978-3-031-23828-4_20.Peer-Reviewed Original ResearchFocal cortical dysplasiaCortical dysplasiaIntracranial monitoringPredictors of seizure freedomIctal onset patternsPost-operative outcomesSurgical decision-making processFrontal lobe epilepsySensorimotor functionDysplastic cortexResection marginsSurgical interventionSeizure freedomEpileptiform patternsLobe epilepsyPharmacoresistant epilepsyMotor cortexOnset patternsDysplasiaCortexPatientsCircuit organizationEpileptiformEpilepsyDominant, Lesional Congenital Hemispheric Epilepsy
Herlopian A, Mahmud S, Mattson R. Dominant, Lesional Congenital Hemispheric Epilepsy. 2024, 699-731. DOI: 10.1007/978-3-031-23828-4_28.Peer-Reviewed Original ResearchCorpus callosotomyPorencephalic cystPartial frontal lobe resectionGeneralized atonic seizuresAnterior corpus callosotomyFrontal lobe resectionStartle-induced seizuresThalamic hypometabolismAtonic seizuresLobe resectionNeuroimaging findingsHemispheric epilepsyCallosotomyPatientsComplex symptomsSeizuresCystsEpilepsyNon-dominant, Non-lesional Orbitofrontal-Plus Epilepsy
Herlopian A. Non-dominant, Non-lesional Orbitofrontal-Plus Epilepsy. 2024, 563-598. DOI: 10.1007/978-3-031-23828-4_23.Peer-Reviewed Original ResearchResection surgeryIntracranial monitoringInterictal PET scanIctal onset patternsPost-operative outcomesNon-lesional epilepsySurgical work-upInterictal epileptiform dischargesNon-invasive modalityDelta slowingEEG findingsInvestigative armamentariumTonic seizuresEpileptiform dischargesPET scansIctal propagationWidespread hypometabolismWork-upInsular epilepsyPsychiatric manifestationsOnset patternsSpike rateEpilepsySurgeryPatientsRasmussen’s Encephalitis and Focal Cortical Dysplasia
Vadiparati A, Herlopian A. Rasmussen’s Encephalitis and Focal Cortical Dysplasia. 2024, 241-286. DOI: 10.1007/978-3-031-23828-4_12.Peer-Reviewed Original ResearchOccipital lobe epilepsyRasmussen encephalitisSurgical interventionLobe epilepsyVisual field analysisSurgical decision-making processFocal cortical dysplasiaLeft occipital lobeAnterior thalamic nucleiClinical presentationCortical dysplasiaMultifocal epilepsySurgical techniqueIntractable seizuresOutcome predictorsDeep brain stimulationThalamic nucleiNeuromodulation therapiesDiagnostic criteriaOccipital lobeOccipital lobectomyProgressive natureEpilepsyBrain stimulationPatientsNon-dominant, Tumor-related Temporal Lobe Epilepsy
Herlopian A. Non-dominant, Tumor-related Temporal Lobe Epilepsy. 2024, 161-174. DOI: 10.1007/978-3-031-23828-4_8.Peer-Reviewed Original ResearchTumor-related epilepsyTumor-related temporal lobe epilepsyPredictor of post-operative outcomesIntra-operative electrocorticographyPost-operative outcomesPre-surgical evaluationTemporal lobe epilepsySurgical approachAdult patientsElectroencephalographic evaluationSemiological differencesMR spectroscopyLobe epilepsyNeuroimaging findingsEpilepsyPatientsLesionsLoss of awarenessMultifocal Epilepsy and Non-dominant Cingulate Lesion
Herlopian A, Gray T, Quraishi I. Multifocal Epilepsy and Non-dominant Cingulate Lesion. 2024, 393-429. DOI: 10.1007/978-3-031-23828-4_18.ChaptersMultifocal epilepsyEEG findings of patientsFindings of patientsAnti-seizure medicationsPrognostic roleSurgical outcomesEEG findingsEEG changesCingulate epilepsyHabitual seizuresIctal tachycardiaAnterior cingulate gyrusEpilepsy monitoring unitVascular lesionsIctal speechPredictive valueOutcome determinantsPatientsMonitor unitsCingulate cortexEpilepsyCingulate gyrusCingulateCortexEEG
2023
Ictal Thalamic Recordings in Patients with Deep Brain Stimulation Targeting Thalamic NucleiIdentify whether ictal thalamic EEG signals could be derived from ambulatory recordings in patients with pharmacoresistant epilepsy treated with deep brain stimulation (DBS) targeting either bilateral anterior thalamic nuclei (ATN) or centromedian nuclei (CMN). (P5-1.008)
Saab L, Jiang J, Quraishi I, Herlopian A. Ictal Thalamic Recordings in Patients with Deep Brain Stimulation Targeting Thalamic NucleiIdentify whether ictal thalamic EEG signals could be derived from ambulatory recordings in patients with pharmacoresistant epilepsy treated with deep brain stimulation (DBS) targeting either bilateral anterior thalamic nuclei (ATN) or centromedian nuclei (CMN). (P5-1.008). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000204225.Peer-Reviewed Original Research
2022
Electroencephalographic changes in purified pharmaceutical cannabidiol therapy
Herlopian A, Barnett JR, Nascimento FA, Lee H, Thiele EA. Electroencephalographic changes in purified pharmaceutical cannabidiol therapy. Epilepsy & Behavior 2022, 128: 108558. PMID: 35078115, DOI: 10.1016/j.yebeh.2022.108558.Peer-Reviewed Original ResearchConceptsInterictal epileptiform dischargesElectroencephalographic changesCBD treatmentIctal findingsSleep architectureEEG changesInvestigational New Drug programPredominant seizure typeNew drug programPre-treatment EEGYears of ageSubjective cognitive improvementElectrographic findingsElectrographic improvementRefractory epilepsySeizure typesClinical outcomesElectrographic changesEpileptiform dischargesPatientsCognitive improvementDrug programsSubstantial associationEEG studiesTreatment