Interrater Reliability of Experts in Identifying Interictal Epileptiform Discharges in Electroencephalograms
Jing J, Herlopian A, Karakis I, Ng M, Halford JJ, Lam A, Maus D, Chan F, Dolatshahi M, Muniz C, Chu C, Sacca V, Pathmanathan J, Ge W, Sun H, Dauwels J, Cole AJ, Hoch DB, Cash SS, Westover MB. Interrater Reliability of Experts in Identifying Interictal Epileptiform Discharges in Electroencephalograms. JAMA Neurology 2020, 77: 49-57. PMID: 31633742, PMCID: PMC6806666, DOI: 10.1001/jamaneurol.2019.3531.Peer-Reviewed Original ResearchConceptsInterictal epileptiform dischargesPercentage of agreementEpileptiform dischargesNumber of IEDsMultivariate logistic regression modelPrimary outcome measureMassachusetts General HospitalLogistic regression modelsPhase 1Secondary outcomesInterrater reliability studyRoutine electroencephalogramMedical recordsGeneral HospitalOutcome measuresMAIN OUTCOMEProspective analysisClinical neurophysiologySubspecialty trainingIndividualized thresholdsSubstantial reliabilityInterrater reliabilityNegative controlPhase 2Electroencephalogram