Heparin-Induced Thrombocytopenia and Cardiac Surgery: A Role for Hematologists in Critical Care Units
Lee A, Sylvester K, Rawn J, Fanikos J, Berliner N. Heparin-Induced Thrombocytopenia and Cardiac Surgery: A Role for Hematologists in Critical Care Units. Blood 2011, 118: 2062. DOI: 10.1182/blood.v118.21.2062.2062.Peer-Reviewed Original ResearchDirect thrombin inhibitorCardiac surgery patientsCardiac surgery intensive care unitPre-test probability scoreCritical care unitsDTI usePostoperative thrombocytopeniaSurgery patientsCare unitAntibody testPF4 antibodiesPOD 0Valve replacementCardiac surgeonsSurgery intensive care unitAntibody-negative casesAntibody-positive casesDeep venous thrombosesOverall clinical courseRadial artery thrombosisSuspicion of HITAortic valve replacementCoronary artery bypassMitral valve replacementPostoperative day 0Clinical Significance of Coagulation Studies in Predicting Response to Recombinant Factor VIIa in Cardiac Surgery Patients
Lee A, Campigotto F, Rawn J, Neuberg D, Kaufman R, Berliner N. Clinical Significance of Coagulation Studies in Predicting Response to Recombinant Factor VIIa in Cardiac Surgery Patients. Blood 2011, 118: 4351. DOI: 10.1182/blood.v118.21.4351.4351.Peer-Reviewed Original ResearchChest tube outputCardiac surgery patientsCoagulation studiesCardiac surgeryUncontrolled hemorrhageTube outputRFVIIa administrationRFVIIa efficacyTransfusion requirementsSurgery patientsRetrospective studyMedical recordsSurvival statusMedian cardiopulmonary bypass timeMultivariable logistic regression analysisStepwise multivariable logistic regression analysisCardiopulmonary bypass timeMedian transfusion requirementStepwise multivariable regression modelsBlood product transfusionVentricular ejection fractionIntraaortic balloon pumpRecombinant factor VIIaLogistic regression analysisMultivariable regression models