Rituximab Does Not Improve Progression Free (PFS) or Overall Survival (OS) in Patients with Limited Stage Diffuse Large B Cell Lymphoma (DLBCL).
Hochberg E, Birrer N, Toomey C, Barnes J, Lee A, LaCasce A, Abramson J. Rituximab Does Not Improve Progression Free (PFS) or Overall Survival (OS) in Patients with Limited Stage Diffuse Large B Cell Lymphoma (DLBCL). Blood 2009, 114: 3755. DOI: 10.1182/blood.v114.22.3755.3755.Peer-Reviewed Original ResearchLimited stage diffuse large B-cell lymphomaDiffuse large B-cell lymphomaLarge B-cell lymphomaUse of rituximabOverall survivalB-cell lymphomaSpeakers bureauCell lymphomaYounger low-risk patientsPrimary diffuse large B-cell lymphomaDana-Farber Cancer InstituteBenefit of rituximabGood-prognosis populationMultiple retrospective analysesAnthracycline-containing chemotherapyOverall survival benefitPatients 18 yearsLow-risk patientsAdvanced-stage patientsCD20 monoclonal antibodyLarge multicenter trialsTumor registry dataYears of ageMassachusetts General HospitalCurative intent