2024
The Impact of Antenatal Corticosteroids on the Metabolome of Preterm Newborns: An Untargeted Approach
Valerio E, Meneghelli M, Stocchero M, Galderisi A, Visentin S, Bonadies L, Pirillo P, Poloniato G, Giordano G, Baraldi E. The Impact of Antenatal Corticosteroids on the Metabolome of Preterm Newborns: An Untargeted Approach. International Journal Of Molecular Sciences 2024, 25: 5860. PMID: 38892043, PMCID: PMC11172597, DOI: 10.3390/ijms25115860.Peer-Reviewed Original ResearchAntenatal corticosteroidsPreterm infantsPreterm newbornsInvasive ventilationClinical outcomesMass spectrometry-based untargeted metabolomics analysisImpact of antenatal corticosteroidsTiming of antenatal corticosteroidsMetabolomic analysisNeonatal intensive care unitPostnatal clinical outcomesPadova University HospitalRecommended time windowUntargeted metabolomics analysisElevated levelsImprove respiratory outcomesIntensive care unitUrinary metabolomeLabor onsetAnti-inflammatory propertiesMetabolomic profilesDepartment of womenUniversity HospitalCare unitRespiratory outcomesImpact of macronutrients intake on glycemic homeostasis of preterm infants: evidence from continuous glucose monitoring
Guiducci S, Res G, Bonadies L, Savio F, Brigadoi S, Priante E, Trevisanuto D, Baraldi E, Galderisi A. Impact of macronutrients intake on glycemic homeostasis of preterm infants: evidence from continuous glucose monitoring. European Journal Of Pediatrics 2024, 183: 3013-3018. PMID: 38637447, PMCID: PMC11192807, DOI: 10.1007/s00431-024-05532-4.Peer-Reviewed Original ResearchPreterm infantsMacronutrient intakeGlucose profilesGestational ageContinuous glucose monitoringNutritional intakeParenteral nutrient intakesGlycemic homeostasisWeeks gestational ageSensor glucoseExposure to hyperglycemiaGlucose monitoringBlood glucose profilesParenteral nutritionHigher lipid intakeMild hypoglycemiaAmino acid intakeSevere hyperglycemiaSevere hypoglycemiaAcid intakeLipid intakeNutrient intakeInfantsPretermHyperglycemia
2023
Early treatment of neonatal diabetes with oral glibenclamide in an extremely preterm infant
Galderisi A, Kermorvant‐Duchemin E, Daruich A, Bonnard A, Lapillonne A, Aubelle M, Perrella B, Vial Y, Cave H, Berdugo M, Jarreau P, Polak M, Beltrand J. Early treatment of neonatal diabetes with oral glibenclamide in an extremely preterm infant. 2023, 64: 161-166. PMID: 36873092, PMCID: PMC9981413, DOI: 10.1002/jmd2.12358.Peer-Reviewed Original ResearchEarly treatmentNeonatal diabetesPreterm babiesPreterm infantsGlucose profilesComplete retinal vascularizationLow glucose intakeBlood glucose testMonth of birthOral glibenclamideGlycemic controlMonth 6Gestational ageNasogastric tubeRetinal vascularizationMaternal milkGlucose intakeInsulin treatmentKCNJ11 genesGlucose testHyperglycemic episodesSpecific treatmentProgressive regressionDiabetesHomozygous variant
2022
Neonatal Hyperglycemia and Neurodevelopmental Outcomes in Preterm Infants: A Review
Guiducci S, Meggiolaro L, Righetto A, Piccoli M, Baraldi E, Galderisi A. Neonatal Hyperglycemia and Neurodevelopmental Outcomes in Preterm Infants: A Review. Children 2022, 9: 1541. PMID: 36291477, PMCID: PMC9600957, DOI: 10.3390/children9101541.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsGriffiths Mental Developmental ScalesInternational trial registriesPreterm infantsNeonatal hyperglycemiaYears of lifeNeurodevelopmental outcomesEarly neonatal hyperglycemiaCochrane Central RegisterLong-term neurodevelopmentQuality of evidenceEffects of hyperglycemiaMovement Assessment BatteryGlucose impairmentCentral RegisterControlled TrialsNeurodevelopment outcomeTrials RegistryCochrane LibraryNeurodevelopment assessmentNeurological delayMotor functionCurrent evidencePRISMA guidelinesHyperglycemiaBayley ScalesGlucose variability increases during minimally invasive procedures in very preterm infants
Galderisi A, Res G, Guiducci S, Savio F, Brigadoi S, Forlani L, Mastrandrea B, Moschino L, Lolli E, Priante E, Trevisanuto D, Baraldi E. Glucose variability increases during minimally invasive procedures in very preterm infants. European Journal Of Pediatrics 2022, 182: 89-94. PMID: 36201017, PMCID: PMC9829573, DOI: 10.1007/s00431-022-04641-2.Peer-Reviewed Original ResearchConceptsVery preterm infantsContinuous glucose monitoringPreterm infantsGlucose variabilityNeonatal stressNappy changeInvasive proceduresMedian glucoseGlucose monitoringNon-invasive procedurePrimary outcomeAbsence of changesHeel prickMean glucoseNeonatal proceduresCare proceduresDay 2InfantsParental presenceGlucose variationCGM dataGlucoseSDNeonatesPrick
2021
Continuous glucose monitoring for the prevention of morbidity and mortality in preterm infants
Galderisi A, Trevisanuto D, Russo C, Hall R, Bruschettini M. Continuous glucose monitoring for the prevention of morbidity and mortality in preterm infants. 2021, 2021: cd013309. PMID: 34931697, PMCID: PMC8690212, DOI: 10.1002/14651858.cd013309.pub3.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsRisk of hypoglycaemiaUse of CGMContinuous glucose monitoringPreterm infantsIntermittent modalitiesRisk ratioEffects of CGMLong-term neurodevelopmental impairmentGlucose monitoringEfficacy of CGMCare Group (EPOC) criteriaPreterm infants 1Cochrane Effective PracticePrevention of morbidityClinical trials databasesLong-term outcomesConfidence intervalsPreterm infant mortalitySafety of CGMImprecision of estimatesFixed-effects modelAdverse neurodevelopmentGRADE approachNeurodevelopmental outcomesDATA COLLECTION
2020
Continuous glucose monitoring for the prevention of morbidity and mortality in preterm infants
Galderisi A, Bruschettini M, Russo C, Hall R, Trevisanuto D. Continuous glucose monitoring for the prevention of morbidity and mortality in preterm infants. 2020, 12: cd013309. PMID: 33348448, PMCID: PMC8092644, DOI: 10.1002/14651858.cd013309.pub2.Peer-Reviewed Original ResearchConceptsPreterm infantsContinuous glucose monitoringGlycemic measuresRisk ratioIntermittent modalitiesLong-term neurodevelopmental impairmentGlucose monitoringCare Group (EPOC) criteriaCochrane Central RegisterCochrane Effective PracticePrevention of morbidityQuasi-randomized trialStandard search strategyClinical trials databasesLong-term outcomesPreterm infant mortalityAllied Health LiteratureUse of CGMImprecision of estimatesFixed-effects modelCochrane NeonatalAdverse neurodevelopmentCentral RegisterGRADE approachControlled Trials
2019
Neonatal Resuscitation: State of the Art
Trevisanuto D, Galderisi A. Neonatal Resuscitation: State of the Art. American Journal Of Perinatology 2019, 36: s29-s32. PMID: 31238355, DOI: 10.1055/s-0039-1691797.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsNeonatal resuscitationSustained lung inflationUmbilical cord milkingInvasive surfactant administrationUmbilical cord clampingManagement of neonatesHeart rate assessmentForthcoming clinical trialsCord clampingSurfactant administrationCord milkingPreterm infantsNew RCTsLaryngeal maskClinical trialsLung inflationRobust scientific evidenceResuscitationLiterature searchRelevant articlesPast yearScientific evidenceDescriptive reviewRCTsNovel evidence
2017
The distance between the delivery room and neonatal intensive care unit had no impact on the respiratory management of preterm infants at birth
Trevisanuto D, Morassutti F, Doglioni N, Avilés C, Galderisi A, Cavallin F. The distance between the delivery room and neonatal intensive care unit had no impact on the respiratory management of preterm infants at birth. Acta Paediatrica 2017, 107: 171-172. PMID: 28981170, DOI: 10.1111/apa.14107.Peer-Reviewed Original Research