Active chemotherapy for sarcomatoid and rapidly progressing renal cell carcinoma
Nanus DM, Garino A, Milowsky MI, Larkin M, Dutcher JP. Active chemotherapy for sarcomatoid and rapidly progressing renal cell carcinoma. Cancer 2004, 101: 1545-1551. PMID: 15378501, DOI: 10.1002/cncr.20541.Peer-Reviewed Original ResearchConceptsSarcomatoid renal cell carcinomaRenal cell carcinomaCell carcinomaAntitumor activityGemcitabine-based regimensGrade 4 toxicityModest antitumor activitySite of metastasisSite of diseaseCombination of doxorubicinInstitutional review boardStable diseaseMedian durationMedian survivalPartial responseRecurrent diseaseComplete responseActive chemotherapyFactor supportMedian timeDuct carcinomaProspective InvestigationInterleukin-2PatientsGemcitabine