2020
Classification and differential effectiveness of goal-directed hemodynamic therapies in surgical patients: A network meta-analysis of randomized controlled trials
Zhao X, Tian L, Brackett A, Dai F, Xu J, Meng L. Classification and differential effectiveness of goal-directed hemodynamic therapies in surgical patients: A network meta-analysis of randomized controlled trials. Journal Of Critical Care 2020, 61: 152-161. PMID: 33171332, DOI: 10.1016/j.jcrc.2020.10.031.Peer-Reviewed Original ResearchConceptsGoal-directed hemodynamic therapyCardiac output optimizationAcute kidney injuryIntravascular volumeSurgical patientsStroke volumeHemodynamic therapyIntravascular volume optimizationStroke volume optimizationCumulative ranking curvePROSPERO registration numberAKI reductionKidney injurySystemic oxygenationCardiac outputMortality reductionOxygen deliveryRegistration numberPatientsVolume optimizationArrhythmiasTherapyMortalityOverall evidenceTrials
2018
Association of conflicts of interest with the results and conclusions of goal-directed hemodynamic therapy research: a systematic review with meta-analysis
Zhang L, Dai F, Brackett A, Ai Y, Meng L. Association of conflicts of interest with the results and conclusions of goal-directed hemodynamic therapy research: a systematic review with meta-analysis. Intensive Care Medicine 2018, 44: 1638-1656. PMID: 30105599, DOI: 10.1007/s00134-018-5345-z.Peer-Reviewed Original ResearchConceptsIndustry-sponsored studiesConflicts of interestPurposeThe associationUsual careRelative riskType of COITherapy researchEligible articlesSystematic reviewPotential associationAuthor conflictsLogistic regressionAvailable evidenceSignificant overall effectComplicationsStudy resultsAssociationIndustry sponsorshipConclusionMixed effectsSignificant relationshipMethodsRandomizedOverall effectNeutral conclusionsMortality