2024
Polypharmacy in elective lumbar spinal surgery for degenerative conditions with 24-month follow-up
Dietz N, Kumar C, Elsamadicy A, Bjurström M, Wong K, Jamieson A, Sharma M, Wang D, Ugiliweneza B, Drazin D, Boakye M. Polypharmacy in elective lumbar spinal surgery for degenerative conditions with 24-month follow-up. Scientific Reports 2024, 14: 25340. PMID: 39455709, PMCID: PMC11511981, DOI: 10.1038/s41598-024-76248-6.Peer-Reviewed Original ResearchConceptsDegenerative lumbar pathologySurgical site infectionSpinal surgeryPolypharmacy groupSite infectionLumbar pathologyFollow-upMedical complicationsElective lumbar spinal surgeryLumbar spinal surgeryUrinary tract infectionDegenerative lumbar conditionsReturn to the emergency departmentTract infectionsNon-polypharmacy groupSurgical patientsLumbar conditionsSurgeryPatientsComplicationsPolypharmacyEmergency departmentPrescribed medicationsMarketScan datasetDegenerative conditionsImpact of Depression on Postoperative Medical and Surgical Outcomes in Spine Surgeries: A Systematic Review and Meta-Analysis
Aghajanian S, Shafiee A, Athar M, Mohammadifard F, Goodarzi S, Esmailpur F, Elsamadicy A. Impact of Depression on Postoperative Medical and Surgical Outcomes in Spine Surgeries: A Systematic Review and Meta-Analysis. Journal Of Clinical Medicine 2024, 13: 3247. PMID: 38892958, PMCID: PMC11172961, DOI: 10.3390/jcm13113247.Peer-Reviewed Original ResearchNon-routine dischargeSpine surgerySurgical complicationsSurgical outcomesStatistically significant higher rateUrinary tract infectionSurgical site infectionDeep vein thrombosisLength of hospitalizationSystematic reviewNon-depressed controlsSignificantly higher ratesUrinary retentionPostoperative medicationTract infectionsPostoperative outcomesPulmonary embolismSite infectionSpinal surgeryVein thrombosisImpact of depressionPooled analysisDepressed patientsHematoma formationHospital length
2017
The Impact of Chronic Kidney Disease on Postoperative Outcomes in Patients Undergoing Lumbar Decompression and Fusion
Adogwa O, Elsamadicy AA, Sergesketter A, Oyeyemi D, Galan D, Vuong VD, Khalid S, Cheng J, Bagley CA, Karikari IO. The Impact of Chronic Kidney Disease on Postoperative Outcomes in Patients Undergoing Lumbar Decompression and Fusion. World Neurosurgery 2017, 110: e266-e270. PMID: 29109065, DOI: 10.1016/j.wneu.2017.10.147.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseCKD groupPatient demographicsKidney diseaseLumbar arthrodesisPreoperative chronic kidney diseaseInferior perioperative outcomesLumbar spine decompressionPostoperative complication profileLength of surgeryPostoperative complication rateEpisode of deliriumUrinary tract infectionDeep vein thrombosisBody mass indexIntensive care unitMajor academic institutionPerioperative complicationsPerioperative outcomesPostoperative complicationsPrimary endpointAdult patientsComplication rateLumbar decompressionPostoperative outcomesDepression as an independent predictor of postoperative delirium in spine deformity patients undergoing elective spine surgery.
Elsamadicy AA, Adogwa O, Lydon E, Sergesketter A, Kaakati R, Mehta AI, Vasquez RA, Cheng J, Bagley CA, Karikari IO. Depression as an independent predictor of postoperative delirium in spine deformity patients undergoing elective spine surgery. Journal Of Neurosurgery Spine 2017, 27: 209-214. PMID: 28574333, DOI: 10.3171/2017.4.spine161012.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAge FactorsComorbidityDecompression, SurgicalDeliriumDepressionElective Surgical ProceduresFemaleHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisOperative TimePostoperative ComplicationsPrognosisRetrospective StudiesRisk FactorsSpinal CurvaturesSpinal FusionSpineConceptsElective spine surgeryMultivariate logistic regression analysisPostoperative deliriumIndependent risk factorPostoperative complication rateSpine surgeryLogistic regression analysisPatient demographicsComplication rateIndependent predictorsDeformity patientsRisk factorsDepression groupAffective disordersSuperficial surgical site infectionSignificant between-group differencesInferior surgical outcomesPostoperative delirium rateResults Patient demographicsInitial hospital stayProportion of patientsRate of complicationsSurgical site infectionUrinary tract infectionDeep vein thrombosisEffects of immediate post-operative pain medication on length of hospital stay: does it make a difference?
Elsamadicy AA, Adogwa O, Fialkoff J, Vuong VD, Mehta AI, Vasquez RA, Cheng J, Bagley CA, Karikari IO. Effects of immediate post-operative pain medication on length of hospital stay: does it make a difference? Journal Of Spine Surgery 2017, 3: 155-162. PMID: 28744495, PMCID: PMC5506320, DOI: 10.21037/jss.2017.04.04.Peer-Reviewed Original ResearchPost-operative pain medicationPatient reported outcomesElective spine surgeryPain medicationUrinary tract infectionSpine surgeryHospital stayComplication ratePatient carePost-operative complication rateSignificant differencesDecreased pain scoresHospital readmission ratesPatient-controlled analgesicMajor academic medical centerAcademic medical centerHealth care costsHealth care dollarsHospital coursePain scoresBaseline characteristicsPatient demographicsReadmission ratesTract infectionsBlood lossIncreased 30-Day Complication Rates Associated with Laminectomy in 874 Adult Patients with Spinal Deformity Undergoing Elective Spinal Fusion: A Single Institutional Study
Elsamadicy AA, Adogwa O, Warwick H, Sergesketter A, Lydon E, Shammas RL, Mehta AI, Vasquez RA, Cheng J, Bagley CA, Karikari IO. Increased 30-Day Complication Rates Associated with Laminectomy in 874 Adult Patients with Spinal Deformity Undergoing Elective Spinal Fusion: A Single Institutional Study. World Neurosurgery 2017, 102: 370-375. PMID: 28359921, DOI: 10.1016/j.wneu.2017.03.096.Peer-Reviewed Original ResearchConceptsElective spinal fusionSpinal fusionSpinal deformityAdult patientsComplication rateComplication Rates AssociatedAllogeneic blood transfusionPostoperative complication rateSingle institutional studyUrinary tract infectionHigh complication rateIntensive care unitMajor academic institutionPatient demographicsReadmission ratesTract infectionsBlood lossBlood transfusionPrimary outcomeWound drainageCare unitIntraoperative durotomyMedical recordsMental statusInstrumentation failure
2016
Impact of Race on 30-Day Complication Rates After Elective Complex Spinal Fusion (≥5 Levels): A Single Institutional Study of 446 Patients
Elsamadicy AA, Adogwa O, Sergesketter A, Hobbs C, Behrens S, Mehta AI, Vasquez RA, Cheng J, Bagley CA, Karikari IO. Impact of Race on 30-Day Complication Rates After Elective Complex Spinal Fusion (≥5 Levels): A Single Institutional Study of 446 Patients. World Neurosurgery 2016, 99: 418-423. PMID: 28003170, DOI: 10.1016/j.wneu.2016.12.029.Peer-Reviewed Original ResearchMeSH KeywordsAgedBlack or African AmericanElective Surgical ProceduresEquipment FailureEthnicityFemaleHumansIntensive Care UnitsIntraoperative ComplicationsLength of StayMaleMiddle AgedOperative TimePain, PostoperativePatient ReadmissionPostoperative ComplicationsRetrospective StudiesSpinal DiseasesSpinal FusionSurgical Wound DehiscenceUrinary Tract InfectionsWhite PeopleConceptsComplex spinal fusionPostoperative complicationsComplication rateSpinal fusionPatient demographicsReadmission ratesSimilar postoperative complicationsSingle institutional studyUrinary tract infectionSpinal fusion outcomesBody mass indexComplex spinal surgeryMajor academic institutionHospital stayTract infectionsAdult patientsPrimary outcomeWhite patientsBlack patientsOperative timeMass indexSurgical outcomesMedical recordsPatient raceSpinal surgeryImpact of Intraoperative Steroids on Postoperative Infection Rates and Length of Hospital Stay: A Study of 1200 Spine Surgery Patients
Elsamadicy AA, Wang TY, Back AG, Sergesketter A, Warwick H, Karikari IO, Gottfried ON. Impact of Intraoperative Steroids on Postoperative Infection Rates and Length of Hospital Stay: A Study of 1200 Spine Surgery Patients. World Neurosurgery 2016, 96: 429-433. PMID: 27667578, DOI: 10.1016/j.wneu.2016.09.057.Peer-Reviewed Original ResearchConceptsIntraoperative steroidsHospital staySpine surgeryInfection ratePostoperative complicationsPatient demographicsUse cohortSteroid useLong-term steroid useSuperficial surgical site infectionDuke University Medical CenterIntraoperative steroid useSpine surgery patientsPostoperative complication ratePostoperative infection rateShorter hospital staySurgical site infectionUrinary tract infectionUniversity Medical CenterLength of operationLower ratesLow infection rateAdult patientsComplication rateSurgery patients