2019
Intraoperative ketamine may increase risk of post-operative delirium after complex spinal fusion for adult deformity correction
Elsamadicy AA, Charalambous LT, Sergesketter AR, Drysdale N, Adil SM, Freedman IG, Williamson T, Kundishora AJ, Camara-Quintana J, Abd-El-Barr MM, Goodwin CR, Karikari IO. Intraoperative ketamine may increase risk of post-operative delirium after complex spinal fusion for adult deformity correction. Journal Of Spine Surgery 2019, 5: 79-87. PMID: 31032442, PMCID: PMC6465460, DOI: 10.21037/jss.2018.12.10.Peer-Reviewed Original ResearchPost-operative deliriumMultivariate nominal-logistic regression analysisComplex spinal fusionIntraoperative ketamine administrationIntraoperative ketamineNominal logistic regression analysisSpinal fusionPatient demographicsKetamine administrationDeformity correctionPrimary complex spinal fusionPost-operative complication rateAdult spine deformity patientsAdult deformity correctionBetter overall patient carePostoperative complication profileProportion of patientsLength of surgeryPost-operative painPost-operative outcomesSpine deformity patientsComplex spinal surgeryOverall patient careRegression analysisMajor academic institution
2017
The prevalence of undiagnosed pre-surgical cognitive impairment and its post-surgical clinical impact in elderly patients undergoing surgery for adult spinal deformity
Adogwa O, Elsamadicy AA, Lydon E, Vuong VD, Cheng J, Karikari IO, Bagley CA. The prevalence of undiagnosed pre-surgical cognitive impairment and its post-surgical clinical impact in elderly patients undergoing surgery for adult spinal deformity. Journal Of Spine Surgery 2017, 3: 358-363. PMID: 29057343, PMCID: PMC5637212, DOI: 10.21037/jss.2017.07.01.Peer-Reviewed Original ResearchElderly patientsAdult degenerative scoliosisCognitive impairmentDischarge institutionalizationHospital stayReadmission ratesDegenerative scoliosisSLUMS scorePoor post-operative outcomesPre-existing cognitive impairmentElective spine surgeryMore postoperative complicationsElective spinal surgeryPost-operative deliriumHospital readmission ratesPost-operative outcomesPre-operative evaluationAdult spinal deformityBaseline cognitive impairmentSevere cognitive impairmentMental status testsNeuro-cognitive impairmentHigh rateMild cognitive impairmentPreoperative cognitionPost-operative delirium is an independent predictor of 30-day hospital readmission after spine surgery in the elderly (≥65years old): A study of 453 consecutive elderly spine surgery patients
Elsamadicy AA, Wang TY, Back AG, Lydon E, Reddy GB, Karikari IO, Gottfried ON. Post-operative delirium is an independent predictor of 30-day hospital readmission after spine surgery in the elderly (≥65years old): A study of 453 consecutive elderly spine surgery patients. Journal Of Clinical Neuroscience 2017, 41: 128-131. PMID: 28262398, DOI: 10.1016/j.jocn.2017.02.040.Peer-Reviewed Original ResearchConceptsPost-operative deliriumIndependent risk factorSpine surgeryElderly patientsReadmission ratesHospital readmissionRisk factorsDelirium patientsComplication rateIndependent predictorsPost-operative complication rateSuperficial surgical site infectionMultivariate logistic regression analysisDuke University Medical CenterConsecutive elderly patientsSpine surgery patientsSurgical site infectionLogistic regression analysisUniversity Medical CenterLower healthcare costsDSM-V criteriaHospital stayUnplanned readmissionPatient demographicsSurgery patients