2019
Cost-Effectiveness of Computed Tomography Angiography in Management of Tiny Unruptured Intracranial Aneurysms in the United States
Wu X, Matouk CC, Mangla R, Forman HP, Gandhi D, Sanelli P, Malhotra A. Cost-Effectiveness of Computed Tomography Angiography in Management of Tiny Unruptured Intracranial Aneurysms in the United States. Stroke 2019, 50: 2396-2403. PMID: 31340732, DOI: 10.1161/strokeaha.119.025600.Peer-Reviewed Original ResearchConceptsComputed tomography angiographyUnruptured intracranial aneurysmsIntracranial aneurysmsTomography angiographyCancer riskCTA surveillanceCost-effective strategyRadiation-induced brain tumorsRadiation-induced cancer riskSubsequent magnetic resonanceBrain cancer riskBetter health outcomesAnnual rupture riskProbabilistic sensitivity analysesRupture riskLower healthcare spendingAggressive managementPatients 30Subarachnoid hemorrhageIncidental detectionPrior historyHigh riskBrain tumorsAneurysmsHealth outcomes
2018
Risk of Radiation-Induced Cancer From Computed Tomography Angiography Use in Imaging Surveillance for Unruptured Cerebral Aneurysms
Malhotra A, Wu X, Chugh A, Mustafa A, Matouk CC, Gandhi D, Sanelli P. Risk of Radiation-Induced Cancer From Computed Tomography Angiography Use in Imaging Surveillance for Unruptured Cerebral Aneurysms. Stroke 2018, 50: 76-82. PMID: 30580703, DOI: 10.1161/strokeaha.118.022454.Peer-Reviewed Original ResearchSurveillance imagingExcess lifetime riskCancer riskAneurysmal ruptureLifetime riskCancer incidenceRadiation Risk Assessment ToolIntracranial aneurysmsLonger surveillance periodsRadiation-induced cancer riskBrain cancer incidenceHigh-risk groupUnruptured cerebral aneurysmsCost-effectiveness/utility analysesBEIR VII reportRisk of radiationNoninvasive imaging modalityRisk assessment toolExcess cancer riskAngiography useImaging surveillanceTomography angiographySurveillance periodRisk groupsCerebral aneurysms