2021
Differentiation of symptomatic and asymptomatic carotid intraplaque hemorrhage using 3D high‐resolution diffusion‐weighted stack of stars imaging
Kim S, Parker D, Roberts J, Treiman G, Alexander M, Baradaran H, de Havenon A, McNally J. Differentiation of symptomatic and asymptomatic carotid intraplaque hemorrhage using 3D high‐resolution diffusion‐weighted stack of stars imaging. NMR In Biomedicine 2021, 34: e4582. PMID: 34296793, DOI: 10.1002/nbm.4582.Peer-Reviewed Original ResearchConceptsApparent diffusion coefficientCarotid diseaseApparent diffusion coefficient valuesDiffusion-weighted (DW) imagingApparent diffusion coefficient measurementsSymptomatic plaquesAsymptomatic plaquesInternal carotid artery plaqueWilcoxon-Mann-Whitney U testIntraplaque hemorrhageCarotid intraplaque hemorrhageCarotid artery plaquesElevated stroke riskAssociated with plaque instabilityImprove detectionSymptomatic statusHealthy subjectsQuantitative diffusion measurementsU testCarotid atherosclerosisArtery plaquesPlaque instabilityPhantom studyStroke riskHemorrhageCarotid Stenosis and Recurrent Ischemic Stroke
Yaghi S, de Havenon A, Rostanski S, Kvernland A, Mac Grory B, Furie KL, Kim AS, Easton JD, Johnston SC, Henninger N. Carotid Stenosis and Recurrent Ischemic Stroke. Stroke 2021, 52: 2414-2417. PMID: 33940954, PMCID: PMC8268075, DOI: 10.1161/strokeaha.121.034089.Peer-Reviewed Original ResearchConceptsHigh-risk transient ischemic attackTransient ischemic attackEffect of clopidogrelMinor ischemic strokeIschemic strokeIschemic stroke riskCarotid stenosisIschemic attackStroke riskCervical internal carotid arteryAddition of clopidogrelDual antiplatelet therapyRecurrent ischemic strokeCox regression modelInternal carotid arteryAntiplatelet therapyPrimary outcomePoint trialCarotid arteryInclusion criteriaClopidogrelAdjusted modelStenosisPatientsStrokeUsing Ultrasound and Inflammation to Improve Prediction of Ischemic Stroke: A Secondary Analysis of the Multi-Ethnic Study of Atherosclerosis
Baradaran H, Delic A, Wong KH, Sheibani N, Alexander M, McNally JS, Majersik JJ, De Havenon A. Using Ultrasound and Inflammation to Improve Prediction of Ischemic Stroke: A Secondary Analysis of the Multi-Ethnic Study of Atherosclerosis. Cerebrovascular Diseases Extra 2021, 11: 37-43. PMID: 33601394, PMCID: PMC7989729, DOI: 10.1159/000514373.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBiomarkersCarotid Intima-Media ThicknessCarotid StenosisFemaleHumansInflammation MediatorsInterleukin-6Ischemic StrokeMaleMiddle AgedPredictive Value of TestsPrognosisProspective StudiesRisk AssessmentRisk FactorsUltrasonography, DopplerUnited StatesVascular StiffnessConceptsIschemic strokeCarotid distensibilityCarotid stenosisMulti-Ethnic StudyInterleukin-6Primary outcomeRisk factorsInflammation measurementsClinical trial inclusion criteriaSecondary analysisPrimary ischemic strokeIncident ischemic strokeTrial inclusion criteriaVascular risk factorsSystolic blood pressureTraditional risk factorsBaseline study visitCox regression modelIschemic stroke riskStroke risk predictionPrimary prevention effortsUltrasound-derived measurementsIncident strokeMean followPatient ageOptimal Carotid Plaque Features on Computed Tomography Angiography Associated With Ischemic Stroke
Baradaran H, Eisenmenger LB, Hinckley PJ, de Havenon AH, Stoddard GJ, Treiman LS, Treiman GS, Parker DL, McNally J. Optimal Carotid Plaque Features on Computed Tomography Angiography Associated With Ischemic Stroke. Journal Of The American Heart Association 2021, 10: e019462. PMID: 33586471, PMCID: PMC8174260, DOI: 10.1161/jaha.120.019462.Peer-Reviewed Original ResearchConceptsMaximum soft plaque thicknessPlaque thicknessIntraluminal thrombusRim signIschemic strokeStroke sourcesPlaque featuresCarotid plaquesMultivariable Poisson regression modelsDiscriminatory valueRetrospective cross-sectional studyVulnerable carotid plaquesCross-sectional studyCarotid plaque featuresSpecific plaque featuresPoisson regression modelsStroke prediction modelsCarotid sourceCarotid stenosisCarotid CTAImaging featuresStenosis categoriesClinical markersTreatment decisionsStenosis
2016
Prediction of Carotid Intraplaque Hemorrhage Using Adventitial Calcification and Plaque Thickness on CTA
Eisenmenger LB, Aldred BW, Kim S, Stoddard GJ, de Havenon A, Treiman GS, Parker DL, McNally JS. Prediction of Carotid Intraplaque Hemorrhage Using Adventitial Calcification and Plaque Thickness on CTA. American Journal Of Neuroradiology 2016, 37: 1496-1503. PMID: 27102316, PMCID: PMC7960279, DOI: 10.3174/ajnr.a4765.Peer-Reviewed Original ResearchConceptsMaximum soft plaque thicknessCarotid intraplaque hemorrhageAdventitial calcificationIntraplaque hemorrhageRim signPlaque thicknessRetrospective cohort studyAtherosclerosis risk factorsMaximum plaque thicknessMultivariable Poisson regressionNASCET stenosisCohort studyAdventitial inflammationRisk factorsPlaque instabilityCarotid arteryHemorrhageUlcerationSoft plaqueStenosisIntraluminal thrombusPoisson regressionFinal modelCalcificationCarotid MRA