Examination of a case of “treatment failure” in long-term psychoanalytic psychotherapy for treatment-resistant depression
Willemsen J, Rost F, Hustinx M, Fonagy P, Taylor D. Examination of a case of “treatment failure” in long-term psychoanalytic psychotherapy for treatment-resistant depression. The International Journal Of Psychoanalysis 2024, 105: 475-495. PMID: 39230487, DOI: 10.1080/00207578.2024.2352827.Peer-Reviewed Original ResearchConceptsTreatment-resistant depressionPsychoanalytic psychotherapyLong-term psychoanalytic psychotherapyLevels of depressionNegative therapeutic reactionExperiences of abandonmentPatients' levels of depressionStructured Clinical AssessmentPost-treatment outcomesTherapeutic relationshipPatterns of repetitionTherapy processTherapeutic reactionDepressionPsychic conflictPsychotherapyInternal worldInner worldClinical assessmentRandomized controlled trialsLack of symbolismDestructive patternsResearch contextInterpretive stanceTherapistsThe complexity of treatment-resistant depression: A data-driven approach
Rost F, Booker T, Gonsard A, de Felice G, Asseburg L, Malda-Castillo J, Koutoufa I, Ridsdale H, Johnson R, Taylor D, Fonagy P. The complexity of treatment-resistant depression: A data-driven approach. Journal Of Affective Disorders 2024, 358: 292-301. PMID: 38697222, DOI: 10.1016/j.jad.2024.04.093.Peer-Reviewed Original ResearchTreatment-resistant depressionPersonality disorderSuicide attemptsChronic course of depressionCourse of depressionCo-occurring problemsDuration of illnessPhysical health problemsAdverse childhood experiencesPhysical health conditionsDepressive illnessPsychiatric diagnosisSuicidal ideationOccupational functioningPersistent depressionSeverely impaired quality of lifeQuality of lifeChildhood experiencesPragmatic randomized controlled trialDepressionChronic courseSuicideRecall biasClinical descriptionImpaired quality of life